Enones
Enones, also known as enals or ketones with an aldehyde group, are a class of organic compounds characterized by the presence of a carbon-carbon double bond (C=C) and a carbonyl group (C=O) in close proximity. Structurally, they can be represented as R-CH=CH-COOH, where R represents an alkyl or aryl group. These compounds play crucial roles in various chemical reactions due to their unique reactivity. Enones are versatile intermediates in organic synthesis and are widely used in the pharmaceutical, agrochemical, and flavor and fragrance industries.
Enones undergo a variety of transformations such as tautomerization, keto-enol互變異構, addition reactions with nucleophiles at the alpha or beta positions, and intramolecular cyclization. The presence of both functional groups in enones allows for their use in構建多種化學反應,這些反應包括但不限于α-或β位的親核加成反應、內(nèi)酯化環(huán)合等。此外,一些特定的enones還具有生物活性,在藥物開發(fā)中展現(xiàn)出潛在的應用價值。
In the pharmaceutical industry, enones have been utilized as precursors for the synthesis of biologically active compounds. Their unique structural features enable efficient and selective transformations, contributing to the development of new drugs with improved therapeutic profiles.
In summary, enones are essential reagents in organic chemistry due to their versatile reactivity and potential applications across various fields such as pharmaceuticals and fragrances.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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3-Hexen-2-one | 763-93-9 | C6H10O |
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3-Penten-2-one, (3E)- | 3102-33-8 | C5H8O |
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1-Octen-3-one | 4312-99-6 | C8H14O |
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5-Methyl-3-hexen-2-one | 5166-53-0 | C7H12O |
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Pentenone | 112454-82-7 | C5H8O |
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3-Nonen-2-one | 14309-57-0 | C9H16O |
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3-Hexen-2-one,5-methyl-, (3E)- | 1821-29-0 | C7H12O |
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1-Octene-4,6-diyn-3-one,8-[(2R,3S)-3-heptyl-2-oxiranyl]- | 126146-63-2 | C17H22O2 |
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Oumarone | 221198-19-2 | C15H24O2 |
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β-Damascone | 23726-91-2 | C13H20O |
Related Literature
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Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
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Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
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Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
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Xinhuan Wang,Shuangfei Cai,Cui Qi Analyst, 2017,142, 2500-2506
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
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