C-Glycosyl Compounds are a unique class of natural products characterized by the presence of an anomeric carbon atom attached to a glycone unit and a non-carbohydrate aglycone. These compounds play crucial roles in various biological processes, including defense mechanisms against pathogens and as signaling molecules between plants and other organisms. C-glycosylation is known for its high stability under various environmental conditions, making these compounds particularly useful for long-term storage applications. Structurally, C-glycosyl compounds can vary widely depending on the nature of the aglycone, which could be a flavonoid, phenolic acid, or other secondary metabolites. Their synthesis in plants is regulated by specific enzymes and often involves complex biosynthetic pathways. Due to their diverse structures and biological activities, these compounds have garnered significant interest from researchers aiming to elucidate their bioactive properties and potential uses in pharmaceuticals. In the pharmaceutical industry, C-glycosyl derivatives are being explored for their therapeutic benefits, including antioxidant, anti-inflammatory, and antimicrobial activities. Additionally, they serve as valuable tools in the development of new drugs and functional food additives due to their unique chemical properties and biological functions.