Beta-hydroxy ketones
Beta-hydroxy ketones are a class of organic compounds characterized by the presence of both a carbonyl group and an hydroxyl group on the same carbon atom, with at least one more carbon atom separating them. These compounds exhibit unique reactivity profiles due to the α,β-unsaturated structure, making them valuable intermediates in various synthetic transformations. They are widely used as key precursors in organic synthesis, particularly in the preparation of flavors, fragrances, and pharmaceuticals. Additionally, beta-hydroxy ketones have found applications in polymer chemistry, serving as monomers or crosslinking agents to improve material properties. Their versatile nature allows for the construction of complex molecules through sequential functionalization, thereby facilitating the development of new chemical entities with desired biological activities.
Related Literature
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M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
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Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
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Chongyang Zhu,Xiaojia Bian,Xin Jia,Ning Tang,Yongqiang Cheng Food Funct., 2020,11, 10635-10644
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Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
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