Aspartic acid and derivatives
Aspartic acid is a naturally occurring amino acid with a strong polar nature, characterized by its two carboxyl groups (-COOH). This dual functionality makes aspartic acid highly versatile in various applications. Derivatives of aspartic acid are compounds derived from it through chemical modification, which can significantly alter their properties and broaden their potential uses.
Common derivatives include esters, amides, and salts, each with unique characteristics that enhance its applicability in pharmaceuticals, cosmetics, and food additives. For instance, aspartame, a well-known sweetener, is an ester derivative of aspartic acid, offering a safe and effective alternative to traditional sugar.
In the pharmaceutical industry, aspartic acid derivatives are used in drug development due to their ability to influence pharmacokinetics and improve solubility. In cosmetics, they can act as preservatives or serve as emulsifiers. As part of food additives, these derivatives contribute to improving taste profiles without altering nutritional content significantly.
Overall, aspartic acid and its derivatives play a crucial role in multiple sectors due to their adaptability and functional properties.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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(S)-2-Formamidosuccinic acid | 19427-28-2 | C5H7NO5 |
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D-Aspartic acid | 1783-96-6 | C4H7NO4 |
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H-Asp-NH2 | 28057-52-5 | C4H8N2O3 |
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Isoasparagine; (±)-form | 2799-13-5 | C4H8N2O3 |
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2-{[2-({1-carboxy-4-[(diaminomethylidene)amino]-3-hydroxybutyl}amino)ethyl]amino}butanedioic acid (non-preferred name) | 91386-17-3 | C12H23N5O7 |
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L-Aspartic-2,3-t2 acid | 73024-86-9 | C4H7NO4 |
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N-(2E)-3-(4-Hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl-L-aspartic Acid (~98%) | 177715-70-7 | C14H15NO7 |
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(2s)-2-[(2-hydroxybenzoyl)amino]butanedioic Acid | 56145-94-9 | C11H11NO6 |
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N-{(2R)-2-[(2-amino-2-oxoethyl)amino]-2-carboxyethyl}-L-aspartic acid | 7611-43-0 | C9H15N3O7 |
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N-Acetyl-L-aspartic acid | 997-55-7 | C6H9NO5 |
Related Literature
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Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
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Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
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Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
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