1-benzoylpiperidines
**1-Benzoylpiperidines**
1-Benzoylpiperidines are a class of organic compounds characterized by the presence of a benzoyl group attached to a piperidine ring. These molecules exhibit diverse structural and functional properties due to their complex molecular architecture, making them valuable in various chemical applications.
Structurally, 1-benzoylpiperidines consist of a six-membered heterocyclic ring with a nitrogen atom, substituted by a benzoyl moiety, which introduces aromaticity and enhances the molecule's reactivity. This unique structure allows for potential interactions with biomolecules such as enzymes, receptors, and ion channels.
In pharmaceutical research, 1-benzoylpiperidines are of particular interest due to their ability to modulate various biological processes. They can serve as lead compounds in drug discovery, acting as agonists or antagonists depending on the specific site of interaction. Furthermore, these molecules have been explored for their potential anti-inflammatory, analgesic, and neuroprotective properties.
In addition to pharmaceutical applications, 1-benzoylpiperidines also find utility in agricultural chemistry, serving as precursors for herbicides or fungicides due to their inherent chemical stability and bioactivity. Their use in synthetic organic chemistry is also notable, where they can be employed in the synthesis of other complex molecules through various functional group transformations.
Overall, 1-benzoylpiperidines represent a versatile class of compounds with significant potential in multiple areas of chemical research and industry.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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CCG-203971 | 1443437-74-8 | C23H21ClN2O3 |
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IKK 16 hydrochloride | 1186195-62-9 | C28H30ClN5OS |
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3-[4-(Piperidine-1-carbonyl)-phenoxymethyl ]-piperidine-1-carboxylic acid tert-butyl ester | 1146080-55-8 | C23H34N2O4 |
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3-(1-benzoylpiperidin-4-yl)propanoic acid | 75999-93-8 | C15H19NO3 |
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(4-bromophenyl)-(4-methylpiperidin-1-yl)methanone | 329713-82-8 | C13H16BrNO |
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Filorexant | 1088991-73-4 | C24H25FN4O2 |
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CCG-100602 | 1207113-88-9 | C21H17ClF6N2O2 |
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Piperidine, 1-(3-iodobenzoyl)- | 121114-31-6 | C12H14INO |
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[4-(4-fluoro-3-hydroxyphenyl)phenyl]-piperidin-1-ylmethanone | 1261982-26-6 | C18H18FNO2 |
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[4-(3-chloro-4-hydroxyphenyl)phenyl]-piperidin-1-ylmethanone | 1261970-28-8 | C18H18ClNO2 |
Related Literature
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Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Yiding Jiao,Liqun Kang,Jasper Berry-Gair,Kit McColl,Jianwei Li,Haobo Dong,Hao Jiang,Ryan Wang,Furio Corà,Dan J. L. Brett,Ivan P. Parkin J. Mater. Chem. A, 2020,8, 22075-22082
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