1-alkyl,2-acylglycerols
1-Alkyl,2-Acylglycerols are a class of lipids characterized by the presence of an alkyl group attached to the 1-position and an acyl group attached to the 2-position on a glycerol backbone. These compounds play a significant role in various biological processes and have been widely used in cosmetics, pharmaceuticals, and food industries due to their unique properties.
Structurally, 1-alkyl,2-acylglycerols consist of a glycerol molecule with an alkyl chain linked at the first position and an acyl group attached at the second position. The length and saturation state of both chains can vary, leading to diverse functional characteristics. These molecules are known for their excellent emulsifying properties, which make them effective in formulating creams, lotions, and other personal care products.
In pharmaceutical applications, 1-alkyl,2-acylglycerols have been explored for their potential in drug delivery systems due to their ability to stabilize hydrophobic drugs. Additionally, they are used as emollients, surfactants, and thickening agents, contributing to the texture and stability of various formulations.
Their biocompatibility and safety profile also make them suitable for direct skin contact products, ensuring effective yet gentle use in consumer goods.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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1-palmityl-2-acetylglycerol | 99945-82-1 | C21H42O4 |
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1,2-Propanediol,3-(hexadecyloxy)-, 2-acetate | 87233-21-4 | C21H42O4 |
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Glycerides, C14-22mono-, acetates | 68990-54-5 | C23H46O4 |
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1-Hexadecyl-2-acetyl-sn-glycerol | 77133-35-8 | C21H42O4 |
Related Literature
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J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
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Alena Koukalová,?árka Pokorná,Aimee L. Boyle,Nestor Lopez Mora,Alexander Kros,Martin Hof,Radek ?achl Nanoscale, 2018,10, 19064-19073
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Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
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J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
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