1,8-naphthalic anhydrides
1,8-Naphthalic Anhydrides are versatile intermediates in organic synthesis, widely used in the production of polyesters, dyestuffs, and pharmaceuticals. Chemically, they consist of two phenolic rings linked by a methylene bridge, with one end capped by an anhydride group. This structure provides them with strong acidity and reactivity towards various nucleophiles, making them excellent precursors for synthesizing complex molecules.
In polyester synthesis, 1,8-naphthalic anhydrides can react with glycols to form naphthylene-based polyesters, which are known for their high melting points and mechanical strength. They also play a crucial role in dye intermediates due to their ability to participate in condensation reactions that lead to the formation of azo dyes and other pigments.
Moreover, these anhydrides find applications in the pharmaceutical industry as building blocks for synthesizing drug molecules, particularly those requiring aromatic rings with specific functional groups. Their high purity and well-defined structure ensure precise control over the synthetic pathway, resulting in reliable product quality.
Overall, 1,8-naphthalic anhydrides offer a broad range of opportunities for chemical modification, making them indispensable tools in modern organic chemistry.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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4-Sulfo-1,8-naphthalic Anhydride Potassium Salt | 71501-16-1 | C12H5KO6S |
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4,5-Dichloronaphthalene-1,8-dicarboxylic anhydride | 7267-14-3 | C12H4Cl2O3 |
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(Z)-coniosclerodinol | 1276043-60-7 | C18H16O7 |
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4-Amino-3,6-disulfo-1,8-naphthalic Anhydride Dipotassium Salt | 79539-35-8 | C12H7KNO9S2 |
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10-bromo-3-oxatricyclo7.3.1.0^{5,13}trideca-1(13),5,7,9,11-pentaene-2,4-dione | 81-86-7 | C12H5BrO3 |
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1,4,5,8-Naphthalenetetracarboxylic acid 1,8-monoanhydride | 52671-72-4 | C14H6O7 |
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4-Chloro-1,8-naphthalic Anhydride | 4053-08-1 | C12H5ClO3 |
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3-Amino-4-hydroxy-1,8-naphthalic anhydride | 134870-46-5 | C12H7NO4 |
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| 52083-11-1 | C12H6O3S |
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5-Hydroxy-1H,3H-benzodeisochromene-1,3-dione | 23204-36-6 | C12H6O4 |
Related Literature
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Bruce Parkinson Energy Environ. Sci., 2010,3, 509-511
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
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Sowmyalakshmi Venkataraman RSC Adv., 2015,5, 73807-73813
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Yu Long,Bing Yuan,Jianrui Niu,Xin Tong,Jiantai Ma New J. Chem., 2015,39, 1179-1185
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