Cas no 98327-87-8 (1.1'-Binaphthyl-2.2'-diphemyl phosphine)

1,1'-Binaphthyl-2,2'-diphenyl phosphine (commonly abbreviated as BINAP) is a chiral diphosphine ligand widely used in asymmetric catalysis. Its rigid binaphthyl backbone and sterically demanding phenyl groups enable high enantioselectivity in transition-metal-catalyzed reactions, such as hydrogenations, cross-couplings, and C–C bond formations. BINAP’s key advantages include its exceptional configurational stability, broad substrate compatibility, and ability to induce high enantiomeric excess in products. It is particularly valued in pharmaceutical and fine chemical synthesis for producing optically active compounds. The ligand’s versatility and reliability make it a cornerstone in asymmetric synthesis, often employed with rhodium, ruthenium, and palladium catalysts to achieve efficient stereocontrol.
1.1'-Binaphthyl-2.2'-diphemyl phosphine structure
98327-87-8 structure
Product Name:1.1'-Binaphthyl-2.2'-diphemyl phosphine
CAS No:98327-87-8
MF:C44H32P2
MW:622.672412872314
MDL:MFCD00010805
CID:61961
PubChem ID:24871738
Update Time:2025-11-05

1.1'-Binaphthyl-2.2'-diphemyl phosphine Chemical and Physical Properties

Names and Identifiers

    • 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • rac-2,2-bis(diphenylphosphino)-1,1-binaphthyl
    • (?-2,2-Bis(diphenylphosphino)-1,1-binaphthyl
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • DL-2,2'-Bis(diphenylphosphino)-1,1'-dinaphthalene
    • (±)-BINAP
    • (±)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • (+/-)-BINAP
    • (S)-(-)-BINAP
    • 1.1’-Binaphthyl-2.2’-diphemyl phosphine
    • 2,2'-Bis(diphenylphosphino)-1,1'-dinaphthalene
    • BINAP
    • rac-BINAP
    • racemic-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl,Rac-BINAP
    • 2,2′-Bis(diphenylphosphino)-1,1′-binaphthalene
    • [1,1′-Binaphthalene]-2,2′-diylbis[diphenylphosphine]
    • (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • (R)-(+)-BINAP
    • (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • (S)-BINAP
    • 2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • (R)-BINAP
    • (+)-Binap
    • (S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • (S)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • (R)-2,2'-Bis(diphenylphosphino)-1
    • racemic-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • [1-(2-diphenylphosphanyl-1-naphthyl)-2-naphthyl]-diphenyl-phosphane
    • HY-Y0982
    • C44H32P2
    • (s)-2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • rac-2,2' bis(diphenylphosphino)-1,1'-binapthyl
    • 2,2'-bis-(diphenylphosphino)-1,1'-binaphthalene
    • (R)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
    • (R)-2,2'-bis(Diphenylphosphino)-1,1'-binaphthyl
    • [rac]-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • B1405
    • 2,2 inverted exclamation mark -Bis(diphenylphosphino)-1,1 inverted exclamation mark -binaphthalene (BINAP)
    • (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'- binaphthyl
    • AMY11668
    • J-400057
    • rac. 2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • (S)-(-)-2,2 inverted exclamation mark -Bis(diphenylphosphino)-1,1 inverted exclamation mark -binaphthalene
    • (rac)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (+/-)-2,2'-bis-diphenylphosphanyl-[1,1']binaphthalenyl
    • (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene, 97%
    • (r)-2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl
    • 2,2'-bis(diphenyl)phosphino-1,1'-binaphthyl
    • 2,2'-bis(diphenylphosphino)-1,1'-bi_naphthyl
    • Binap, (+)-
    • 1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane)
    • (s)-2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • 2,2'-bis(diphenylphosphino)-1,1-binaphthyl
    • BCP22541
    • Binap (R)-(+)-form [MI]
    • rac-2,2'bis(diphenylphosphino)-1,1'-binaphthyl
    • (R)-(+)-2,2-BIS(DIPHENYLPHOSPHINO)-1,1-BINAPHTHYL
    • 2,2'-bis(diphenylphosphino)-1,1' binaphthyl
    • racemic 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • 2,2'-bis-(diphenylphosphino)-1,1'-binaphtyl
    • 1,1-binaphthalene-2,2'-diylbis(diphenylphosphine)
    • 2,2'-bis(diphenyphosphino)-1,1'binaphthyl
    • MFCD00010805
    • Q795991
    • rac-2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthyl
    • (1,1'-Binaphthalene)-2,2'-diylbis(diphenylphosphine)
    • 76189-55-4
    • racemic 2,2'-Bis(diphenyl-phosphino)-1,1'-binaphthyl
    • racemic (-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • racemic 2,2'-bis-diphenylphosphanyl-[1,1']binaphthalenyl
    • 2,2'-bis-diphenylphosphanyl-[1,1]binaphthalenyl
    • s-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • 2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • (s)-(-)2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • rac-2,2'-bis-diphenylphosphanyl-[1,1']binaphthalenyl
    • R-(+)-1.1'-Binaphthyl-2.2'-diphemyl phosphine R-BINAP
    • 2,2'-Bis(diphenylphosphino)-1,1'-binapthyl
    • FT-0604002
    • (+/-) BINAP
    • HY-Y0003
    • rac-2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • Phosphine, 1,1'-((1S)-(1,1'-binaphthalene)-2,2'-diyl)bis(1,1-diphenyl-
    • (r)-2,2'-bis(diphenylphosphino)-1, 1'-binaphthyl
    • ( inverted exclamation markA)-BINAP
    • (+/-)-2,2'-Bis(diphenylphosphino-)1,1'-binaphthalene
    • (+/-)-2,2'-bis(diphenylphosphino)-1,1-binaphtalene
    • rac-2,2' bis(diphenylphosphino)-1,1'-binaphtyl
    • CS-D1438
    • 2,2'-bis(diphenylphosphino)-1,1'-binaphtalene
    • (rac)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • J-400050
    • racemic-2,2'-bis(diphenylphosphino)1.1'-binaphthyl
    • eisaa03
    • racemic 2,2'-bis (diphenylphosphino)-1,1'-binaphthyl
    • racemic 2,2'-bis(diphenylphosphino)-1,1'-binaphtalene
    • FT-0604001
    • (r)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • (+/-) 2,2'-bis(diphenylphosphino)binaphthyl
    • (+/-)-2,2'-bis(diphenylphosphino)-1,1-binaphthyl
    • racemic-2,2'-bis(diphenylphosphino)-1,1 '-binaphthyl
    • (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene, puriss.
    • (+) racemic-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • InChI=1/C44H32P2/c1-5-19-35(20-6-1)45(36-21-7-2-8-22-36)41-31-29-33-17-13-15-27-39(33)43(41)44-40-28-16-14-18-34(40)30-32-42(44)46(37-23-9-3-10-24-37)38-25-11-4-12-26-38/h1-32H
    • (r)-2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • rac-1,1'-binaphthalene-2,2'diylbis(diphenylphosphane)
    • 2-(DIPHENYLPHOSPHINO)-1-(2-(DIPHENYLPHOSPHINO)NAPHTHALEN-1-YL)NAPHTHALENE
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • rac-2,2'-bis(diphenylphosphino)1,1'-binaphthyl
    • racemic-2,2'bis(diphenylphosphino)-1,1'-binapthyl
    • rac-2,2'-bis-diphenylphosphanyl-[1,1']binaphthalene
    • (r)-(+)-2,2'-bis (diphenylphosphino)-1,1'-binaphthyl
    • 2,2'-bis(diphenylphosphino)-1,1'binaphthalene
    • (+/-)-(1,1-binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • AC-6136
    • (R)-Bis(diphenylphosphino)-1,1'-binaphthyl
    • rac-2,2'-bis(diphenylphoshino)-1,1'-binaphthyl
    • 2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • R(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • SCHEMBL5107
    • (+/-) 2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • DTXSID40913327
    • (+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (S)-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • rac-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • rac-1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane)
    • (r)-(+)2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • AC-4973
    • rac-2,2'-bis(diphenylphosphino)-1,1-binaphthyl
    • A851961
    • Phosphine, [1,1'-binaphthalene]-2,2'-diylbis[diphenyl-
    • 2,2'-bis(diphenylphosphino) 1,1'-binaphthyl
    • (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • 2,2'-bis(diphenyphosphino)-1,1'-binaphthyl
    • CS-W009018
    • (R)-(+)-2,2'-Bis(diphenylphosphino)-[1,1']-binaphthyl
    • 2,2'-bis(diphenyl-phosphino)-1,1'-binaphthyl
    • BCP09621
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphtalene
    • Phosphine, 1,1'-((1R)-(1,1'-binaphthalene)-2,2'-diyl)bis(1,1-diphenyl-
    • (+,-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (s)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • RAC-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL
    • (+/-)-(1,1'-Binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • racemic-2,2'- bis(diphenylphosphino)-1,1'-binaphthyl
    • (rac)-2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • MUALRAIOVNYAIW-UHFFFAOYSA-
    • (R)-(+)-2,2 inverted exclamation mark -Bis(diphenylphosphino)-1,1 inverted exclamation mark -binaphthalene
    • (S)-2,2'-bis(diphenylphosphaneyl)-1,1'-binaphthalene
    • SY009826
    • rac-BINAP, 97%
    • 2,2'-bis-diphenylphosphanyl-[1,1']binaphthalene
    • (+/-)-2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • racemic-2,2'-bis(diphenyl phosphino)-1,1'-binaphthyl
    • (R)-2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthalene
    • racemic 2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • 1,1'-[(1R)-[1,1'-binaphthalene]-2,2'-diyl]bis[1,1-diphenyl-Phosphine
    • 970O8508MB
    • 4F1X2F8NA3
    • (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene
    • (R)- (+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (1,1'-binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • OX12238KWH
    • B1406
    • 2,2'-bis (diphenylphosphino)-1,1-binaphthyl
    • 2,2'-Bis(diphenylphosphino)-1,1'-binapthalene
    • (S)-2,2'-Bis-(diphenylphosphino)-1,1'-binaphthyl
    • racemic 2,2'-bis(diphenylphosphino)- 1,1'-binaphthyl
    • rac-2,2'bis(diphenylphosphino)-1,1'-binaphtyl
    • s-binap
    • Phosphine, 1,1'-(1,1'-binaphthalene)-2,2'-diylbis(1,1-diphenyl-
    • (+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • (1S)-(1,1'-Binaphthalene)-2,2'-diylbis(diphenylphosphine)
    • (s)-2,2'-bis (diphenylphosphino)-1,1'-binaphthyl
    • racemic 2,2'- bis(diphenylphosphino)-1,1'-binaphthyl
    • CHEMBL1275990
    • (S)-(-)-2,2'- Bis(diphenylphosphino)-1,1'-binaphthyl
    • 1.1'-Binaphthyl-2.2'-diphemyl phosphine
    • racemic (+/-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • 2,2'-bis (diphenylphosphino)1,1'-binaphthyl
    • HY-W017757
    • 2,2'-Bis-diphenylphosphanyl-[1,1']binaphthalenyl
    • racemic-2,2'-bis(diphenylphosphino)-1,1' binaphthyl
    • AB89317
    • STR04296
    • UNII-970O8508MB
    • (r)-2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • S-(+)-1.1'-Binaphthyl-2.2'-diphemyl phosphine S-BINAP
    • [2'-(diphenylphosphanyl)-[1,1'-binaphthalene]-2-yl]diphenylphosphane
    • (+/-) racemic-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • Binap, (+/-)-
    • (s)(-)2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl;(+/-)-BINAP
    • A845841
    • F0001-2326
    • (r)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • 2,2'-bis (diphenylphosphino)-1,1'-binaphthyl
    • 2,2'-bis(diphenylphosphino)-1,1'binapthalene
    • A838633
    • 76189-56-5
    • Binap (S)-(-)-form [MI]
    • 2,2'bis(diphenylphosphino)-1,1'-binaphthyl
    • F10169
    • racemic-2,2'-bis(diphenylphosphino)-1,1-binaphthyl
    • racemic-2,2'bis(diphenylphosphino)-1,1'binaphthyl
    • 2,2'-bisdiphenylphosphanyl-[1,1']binaphthalenyl
    • SY002426
    • SY009827
    • (+/-)-2,2;-Bis(diphenylphosphino)-1,1;-binaphthyl
    • BCP22528
    • racemic 2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • 2,2'-Bis (diphenylphosphino)-1,1'-binaphtyl
    • UNII-OX12238KWH
    • (S)-2,2'-BIS(DIPHENYLPHOSPHINO)-1,1'-BINAPHTHYL
    • rac-2,2'-bis(diphenyl-phosphino)-1,1'-binaphthyl
    • (-)-Binap
    • AC-6135
    • 2,2'-bisdiphenylphosphino-1,1'-binaphthyl
    • FT-0609184
    • (+/-) 2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • (+/-)-2,2'-bis(diphenylphos-phino)-1,1'-binaphthyl
    • Binap [MI]
    • 2,2'-Bis(diphenylphosphino)1,1'-binaphthyl
    • BP-10465
    • 2,2'-Bis-(diphenylphosphino)-1,1'-binaphthalin
    • rac-2,2' bis(diphenylphosphino)-1,1'-binaphthyl
    • (+/-)binap
    • 98327-87-8
    • AKOS005259910
    • [1-(2-diphenylphosphanylnaphthalen-1-yl)naphthalen-2-yl]-diphenylphosphane
    • 2,2'-bis-(diphenylphosphino)-1,1'-binaphthy I
    • rac-2,2'-bis-(diphenylphosphino)-1,1'-binaphthalene
    • (Rac)-BINAP
    • (+/-)-2,2'-bis(diphenyl-phosphino)-1,1'-binaphthyl
    • rac-2,2'-bis (diphenylphosphino)-1,1'-binaphthyl
    • rac-2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • (S)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthalene
    • racemic 2,2'-bis(diphenylphosphino)-1,1'-binapthyl
    • r-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthalene
    • 2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthalene
    • (r)(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
    • Binap, (-)-
    • F13334
    • racemic-2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • (R)-(+)-(1,1'-Binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • 2,2'-bis(diphenyl-phosphino)-1,1'-binaphthalene
    • rac-2,2'-bis-diphenylphosphanyl-[1,1]binaphthalenyl
    • (S)-2,2'-bis(diphenylphophino)-1,1'-binaphthyl
    • (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene, 97%
    • (R)-(+)-2,2 bis(diphenylphosphino)-1,1-binaphthyl
    • CS-W018481
    • [1-[2-di(phenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-di(phenyl)phosphane
    • 2,2'-bis(diphenylphosphino)-1,1'-bi naphthyl
    • rac-2,2'-bis (diphenylphosphino)-1,1'-binaphtyl
    • 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl
    • UNII-4F1X2F8NA3
    • 2,2'-Bis(diphenylphosphino)-1,1'binapthyl
    • B2383
    • racemic (1,1'-binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • (+)-2,2'-bis(diphenylphosphino)-1,1'binaphthyl
    • racemic-2,2'-bis(diphenylphosphino)-1,1'-binaphtyl
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl,98%
    • 2,2\\'-Bis(diphenylphosphino)-1,1\\'-binaphthalene
    • (R)-(+)-2,2\\'-Bis(diphenylphosphino)-1,1\\'-binaphthyl
    • BBL103071
    • (+/-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene;(+/-)-(1,1'-Binaphthalene-2,2'-diyl)bis(diphenylphosphine)
    • DB-009478
    • (S)-(-)-2,2\\'-Bis(diphenylphosphino)-1,1\\'-binaphthyl
    • (R)-(+)-2,2 inverted exclamation marka-Bis(diphenylphosphino)-1,1 inverted exclamation marka-binaphthalene
    • 1,1'-[(1R)-[1,1'-Binaphthalene]-2,2'-diyl]bis[1,1-diphenyl-phosphine; (+)-(1R)-[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]; (R)-(+)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl; (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene;
    • 1,1'-[(1S)-[1,1'-Binaphthalene]-2,2'-diyl]bis[1,1-diphenyl-phosphine; (1S)-[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]; (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthalene; (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl;
    • STL556881
    • (R)-(+)-2,2'-Bis(diphenyphosphino)-1,1'-binaphthyl
    • MDL： MFCD00010805
    • Inchi： 1S/C44H32P2/c1-5-19-35(20-6-1)45(36-21-7-2-8-22-36)41-31-29-33-17-13-15-27-39(33)43(41)44-40-28-16-14-18-34(40)30-32-42(44)46(37-23-9-3-10-24-37)38-25-11-4-12-26-38/h1-32H
    • InChI Key： MUALRAIOVNYAIW-UHFFFAOYSA-N
    • SMILES： P(C1C=CC=CC=1)(C1C=CC=CC=1)C1=CC=C2C=CC=CC2=C1C1=C2C=CC=CC2=CC=C1P(C1C=CC=CC=1)C1C=CC=CC=1
    • BRN： 5321443

Computed Properties

  • Exact Mass: 650.22900
  • Monoisotopic Mass: 622.198
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 46
  • Rotatable Bond Count: 7
  • Complexity: 797
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • XLogP3: 11.4
  • Topological Polar Surface Area: 0

Experimental Properties

  • Color/Form: White or cream crystalline powder
  • Density: 0.9710
  • Melting Point: 282°C(lit.)
  • Boiling Point: 724.3°C at 760 mmHg
  • Flash Point: 419℃
  • Refractive Index: 235 ° (C=0.3, Toluene)
  • Water Partition Coefficient: Soluble in tetrahydrofuran, benzene and dichloromethane. Slightly soluble in ether, methanol and ethanol. Insoluble in water.
  • PSA: 27.18000
  • LogP: 10.92580
  • Merck: 1223
  • Sensitiveness: Air Sensitive
  • Solubility: Not determined
  • Specific Rotation: 240 o (C=0.3, TOLUENE)

1.1'-Binaphthyl-2.2'-diphemyl phosphine Security Information

1.1'-Binaphthyl-2.2'-diphemyl phosphine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
481084-5G
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SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
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SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
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SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R005162-25g
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 ￥344 2024-07-19
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
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(CAS:98327-87-8)1.1'-Binaphthyl-2.2'-diphemyl phosphine
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(CAS:98327-87-8)[1-(2-diphenylphosphanyl-1-naphthyl)-2-naphthyl]-diphenyl-phosphane
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(CAS:98327-87-8)(±)-2,2-雙-(二苯膦基)-1,1-聯(lián)萘
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1.1'-Binaphthyl-2.2'-diphemyl phosphine Spectrogram

13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

1.1'-Binaphthyl-2.2'-diphemyl phosphine Related Literature

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Additional information on 1.1'-Binaphthyl-2.2'-diphemyl phosphine

Introduction to 1.1'-Binaphthyl-2.2'-diphemyl phosphine (CAS No. 98327-87-8) and Its Emerging Applications in Chemical Biology

1.1'-Binaphthyl-2.2'-diphemyl phosphine, identified by the CAS number 98327-87-8, is a sophisticated organophosphorus compound that has garnered significant attention in the field of chemical biology due to its unique structural and electronic properties. This binaphthyl-based phosphine derivative exhibits remarkable chiral characteristics, making it a valuable scaffold for the development of asymmetric catalysis, ligand design, and pharmaceutical intermediates. The compound's dual functionality, arising from the combination of the binaphthyl moiety and the phosphine group, enables it to interact selectively with various biomolecules, thereby opening new avenues in drug discovery and molecular recognition.

The binaphthyl core of 1.1'-Binaphthyl-2.2'-diphemyl phosphine contributes to its rigidity and stability, which are essential for its role as a ligand in transition metal-catalyzed reactions. Recent studies have highlighted its utility in promoting highly enantioselective transformations, such as cross-coupling reactions and hydrogenations, which are pivotal in constructing complex organic molecules. The phosphine group, on the other hand, provides a handle for further functionalization, allowing chemists to tailor the compound's properties for specific applications.

In the realm of pharmaceutical research, 1.1'-Binaphthyl-2.2'-diphemyl phosphine has been explored as a potential chiral auxiliary in the synthesis of therapeutics that require precise stereochemical control. Its ability to stabilize chiral centers has been leveraged in the development of novel antibiotics and anti-inflammatory agents. Furthermore, the compound's interaction with biological targets has been investigated, revealing its potential as a tool for probing enzyme mechanisms and designing molecular probes.

Recent advancements in computational chemistry have enabled a deeper understanding of the electronic structure of 1.1'-Binaphthyl-2.2'-diphemyl phosphine, which has informed the design of derivatives with enhanced catalytic activity. For instance, modifications to the substituents on the binaphthyl ring have been shown to modulate the compound's ligand properties, leading to improved performance in asymmetric synthesis. These findings underscore the importance of structure-activity relationships in optimizing organophosphorus compounds for industrial applications.

The compound's versatility also extends to materials science, where it has been employed in the development of organic semiconductors and light-emitting diodes (OLEDs). Its rigid framework and tunable electronic characteristics make it an attractive candidate for designing materials with tailored optoelectronic properties. Additionally, research has demonstrated its potential in stabilizing reactive intermediates in polymer synthesis, contributing to the creation of novel polymeric materials with enhanced durability and functionality.

From a synthetic chemistry perspective, 1.1'-Binaphthyl-2.2'-diphemyl phosphine serves as a versatile building block for constructing more complex molecules. Its reactivity with various electrophiles and nucleophiles has been harnessed to develop multi-step synthetic routes to pharmacologically relevant scaffolds. The compound's ability to undergo selective transformations under mild conditions aligns well with green chemistry principles, reducing waste and energy consumption in synthetic processes.

The growing interest in 1.1'-Binaphthyl-2.2'-diphemyl phosphine is also driven by its potential applications in nanotechnology and biomedicine. For instance, its chiral properties have been exploited in designing nanocarriers for drug delivery systems that exhibit high specificity for target tissues. Moreover, its interaction with biomolecules has been studied as a means of developing biosensors capable of detecting specific analytes with high sensitivity.

In conclusion, 1.1'-Binaphthyl-2.2'-diphemyl phosphine (CAS No. 98327-87-8) represents a promising compound with diverse applications across multiple scientific disciplines. Its unique structural features and functional versatility make it an indispensable tool for researchers aiming to push the boundaries of chemical biology and materials science. As our understanding of its properties continues to evolve, it is expected that this compound will play an increasingly pivotal role in shaping future advancements in these fields.

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(CAS:98327-87-8)1.1'-Binaphthyl-2.2'-diphemyl phosphine
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Amadis Chemical Company Limited
(CAS:98327-87-8)[1-(2-diphenylphosphanyl-1-naphthyl)-2-naphthyl]-diphenyl-phosphane
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