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  Hailing Chen,Lu Yin,Meng Liu,Laibing Wang,Michiya Fujiki,Wei Zhang RSC Adv., 2019,9, 4849-4856
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  Connor J. Taylor,Hikaru Seki,Friederike M. Dannheim,Mark J. Willis,Graeme Clemens,Brian A. Taylor,Thomas W. Chamberlain,Richard A. Bourne React. Chem. Eng., 2021,6, 1404-1411
• 4. An antimonate pyrochlore (H1.23Sr0.45SbO3.48) for photocatalytic oxidation of benzene: effective oxygen usage and excellent activity?
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2,4,6-Trichloro-3,5-dimethyl-pyridine

2,4,6-Trichloro-3,5-dimethyl-pyridine (CAS No. 98274-04-5) is a synthetic organic compound with a unique chemical structure that has garnered attention in various scientific and industrial applications. This compound belongs to the family of pyridine derivatives, which are widely studied for their diverse chemical properties and potential uses in fields such as agriculture, pharmaceuticals, and materials science.

The molecular structure of 2,4,6-Trichloro-3,5-dimethyl-pyridine consists of a pyridine ring with three chlorine atoms at positions 2, 4, and 6, and two methyl groups at positions 3 and 5. This substitution pattern imparts specific electronic and steric properties to the molecule. Recent studies have highlighted its role as a precursor in the synthesis of bioactive compounds, particularly in the development of novel pesticides and herbicides.

One of the most notable applications of 2,4,6-Trichloro-3,5-dimethyl-pyridine is in the field of agrochemicals. Researchers have explored its potential as an intermediate in the synthesis of pyridine-based insecticides. For instance, a study published in *Journal of Agricultural and Food Chemistry* demonstrated that derivatives of this compound exhibit significant activity against agricultural pests such as *Helicoverpa armigera*, a major crop pest globally.

In addition to its pesticidal applications, 2,4,6-Trichloro-3,5-dimethyl-pyridine has been investigated for its role in pharmaceutical chemistry. The compound serves as a building block for synthesizing bioactive molecules with potential therapeutic applications. A recent study in *European Journal of Medicinal Chemistry* reported that derivatives of this compound exhibit anti-inflammatory and antioxidant properties, making them promising candidates for drug development.

The synthesis of 2,4,6-Trichloro-3,5-dimethyl-pyridine involves a multi-step process that typically begins with chlorination of a suitable pyridine derivative followed by alkylation to introduce the methyl groups. Recent advancements in catalytic methods have improved the efficiency and selectivity of these reactions. For example, the use of palladium catalysts has been shown to enhance the yield and purity of the final product.

From an environmental perspective, understanding the fate and transport of 2,4,6-Trichloro-3,5-dimethyl-pyridine in natural systems is crucial for assessing its potential ecological risks. Studies conducted by environmental scientists have focused on its degradation pathways under various conditions. Research published in *Environmental Science & Technology* revealed that the compound undergoes microbial degradation in soil systems under aerobic conditions.

Moreover, 2,4,6-Trichloro-3,demethyl-pyridine has been utilized in materials science for developing advanced materials with tailored properties. Its ability to act as a ligand in coordination chemistry has led to its use in synthesizing metal-organic frameworks (MOFs) with applications in gas storage and catalysis.

In conclusion,2 ,4 ,6 -Trichloro -3 ,5 -dimethyl -pyridine (CAS No .98274 -04 -5 ) is a versatile compound with a wide range of applications across multiple disciplines . Its unique chemical structure , coupled with recent advancements in synthesis and application techniques , continues to make it an area of active research . As scientific understanding deepens , this compound is expected to play an increasingly important role in both industrial and academic settings .

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