Cas no 95853-51-3 (2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine)

2-4-(Sulfanylmethyl)-1,3-thiazol-2-ylguanidine is a specialized organic compound featuring a thiazole core functionalized with a sulfanylmethyl group and a guanidine moiety. This structure imparts unique reactivity, making it valuable in synthetic chemistry and pharmaceutical research. The thiazole ring contributes to stability and potential bioactivity, while the sulfanylmethyl group enhances solubility and offers a reactive site for further derivatization. The guanidine functionality provides strong basicity and hydrogen-bonding capacity, useful in catalysis or molecular recognition applications. Its well-defined molecular architecture allows precise modifications, making it a versatile intermediate for developing bioactive molecules or functional materials. Careful handling is advised due to potential sensitivity of the sulfhydryl group.
2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine structure
95853-51-3 structure
Product Name:2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine
CAS No:95853-51-3
MF:C5H8N4S2
MW:188.273817062378
CID:1001732
PubChem ID:13392596
Update Time:2025-08-04

2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine Chemical and Physical Properties

Names and Identifiers

    • 2-GIANIDINOTHIAZOLE-4-METHYLTHIOL
    • 2-[4-(sulfanylmethyl)-1,3-thiazol-2-yl]guanidine
    • Guanidine,[4-(mercaptomethyl)-2-thiazolyl]
    • SCHEMBL8409815
    • 2-[4-(Sulfanylmethyl)-1.3-thiazol-2-yl]guanidine
    • 95853-51-3
    • AKOS006304794
    • Guanidine, [4-(mercaptomethyl)-2-thiazolyl]-
    • DTXSID30539171
    • N''-[4-(Sulfanylmethyl)-1,3-thiazol-2-yl]guanidine
    • 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine
    • Inchi: 1S/C5H8N4S2/c6-4(7)9-5-8-3(1-10)2-11-5/h2,10H,1H2,(H4,6,7,8,9)
    • InChI Key: AHNNULCXEIGUHA-UHFFFAOYSA-N
    • SMILES: S1C(/N=C(\N)/N)=NC(=C1)CS

Computed Properties

  • Exact Mass: 188.01900
  • Monoisotopic Mass: 188.01903862g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 157
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.1
  • Topological Polar Surface Area: 107?2

Experimental Properties

  • PSA: 141.83000
  • LogP: 1.75130

2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine Security Information

2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
S689265-25mg
2-[4-(Sulfanylmethyl)-1.3-thiazol-2-yl]guanidine
95853-51-3
25mg
$201.00 2023-05-17
TRC
S689265-100mg
2-[4-(Sulfanylmethyl)-1.3-thiazol-2-yl]guanidine
95853-51-3
100mg
$758.00 2023-05-17
TRC
S689265-250mg
2-[4-(Sulfanylmethyl)-1.3-thiazol-2-yl]guanidine
95853-51-3
250mg
$ 1200.00 2023-09-06

Additional information on 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine

Comprehensive Overview of 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine (CAS No. 95853-51-3): Properties, Applications, and Research Insights

The compound 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine (CAS No. 95853-51-3) is a specialized organic molecule that has garnered significant attention in pharmaceutical and biochemical research. Its unique structure, featuring a thiazole ring and a guanidine moiety, makes it a promising candidate for various applications, including drug development and material science. Researchers are particularly interested in its potential as a bioactive scaffold, given its ability to interact with biological targets such as enzymes and receptors.

In recent years, the demand for sulfur-containing heterocycles like 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine has surged due to their versatility in medicinal chemistry. The compound's sulfanylmethyl group enhances its reactivity, enabling it to participate in diverse chemical transformations. This property aligns with the growing trend of designing multifunctional ligands for targeted therapies, a hot topic in precision medicine. Scientists are also exploring its role in antioxidant and anti-inflammatory pathways, addressing common health concerns such as oxidative stress and chronic inflammation.

From a synthetic perspective, CAS No. 95853-51-3 is often discussed in the context of green chemistry and sustainable synthesis. Researchers are optimizing its production to minimize environmental impact, a priority for industries adhering to ESG (Environmental, Social, and Governance) principles. The compound's thiazole core is also a focal point for AI-driven drug discovery, as machine learning models increasingly predict its interactions with proteins, accelerating the development of novel therapeutics.

Beyond pharmaceuticals, 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine has potential applications in agrochemicals and material science. Its chelating properties make it useful in designing metal-organic frameworks (MOFs), which are pivotal in catalysis and gas storage. Additionally, its thiol group offers opportunities for surface modification in nanotechnology, a field gaining traction for innovations in wearable electronics and energy storage.

For researchers and industry professionals, understanding the structure-activity relationship (SAR) of 95853-51-3 is critical. Recent studies highlight its synergistic effects when combined with other bioactive molecules, a strategy employed in combination therapy for complex diseases. This aligns with the rising popularity of polypharmacology, where multi-target compounds are designed to enhance efficacy and reduce side effects.

In summary, 2-4-(Sulfanylmethyl)-1.3-thiazol-2-ylguanidine (CAS No. 95853-51-3) represents a multifaceted compound with broad scientific and industrial relevance. Its integration into cutting-edge research underscores its value in addressing contemporary challenges in healthcare, sustainability, and technology. As advancements in computational chemistry and high-throughput screening continue, this compound is poised to play an even greater role in innovation.

Recommended suppliers
Suzhou Genelee Bio-Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Suzhou Genelee Bio-Technology Co., Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Beyond Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hubei Cuiyuan Biotechnology Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Hubei Cuiyuan Biotechnology Co.,Ltd
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd