Cas no 951624-79-6 (2-Bromo-4,6-difluorobenzenesulfonamide)

2-Bromo-4,6-difluorobenzenesulfonamide is a halogenated benzenesulfonamide derivative with potential applications in pharmaceutical and agrochemical synthesis. Its key structural features—bromine and fluorine substituents on the aromatic ring—enhance reactivity and selectivity in cross-coupling and nucleophilic substitution reactions. The sulfonamide moiety further contributes to its utility as a versatile intermediate in medicinal chemistry, particularly in the development of enzyme inhibitors or bioactive molecules. This compound exhibits high purity and stability under standard conditions, making it suitable for precision synthetic workflows. Its well-defined molecular structure allows for predictable reactivity, facilitating its use in targeted organic transformations.
2-Bromo-4,6-difluorobenzenesulfonamide structure
951624-79-6 structure
Product Name:2-Bromo-4,6-difluorobenzenesulfonamide
CAS No:951624-79-6
MF:C6H4BrF2NO2S
MW:272.067266464233
MDL:MFCD08704578
CID:3158689
PubChem ID:16793741
Update Time:2025-10-19

2-Bromo-4,6-difluorobenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • 2-Bromo-4,6-difluorobenzenesulfonamide
    • EN300-270535
    • DTXSID30588604
    • 951624-79-6
    • MFCD08704578
    • FS-4882
    • SCHEMBL2775058
    • 2-Bromo-4,6-difluorobenzene-1-sulfonamide
    • AKOS000147204
    • BNB62479
    • MDL: MFCD08704578
    • Inchi: 1S/C6H4BrF2NO2S/c7-4-1-3(8)2-5(9)6(4)13(10,11)12/h1-2H,(H2,10,11,12)
    • InChI Key: NHXOSMOBFMOMNZ-UHFFFAOYSA-N
    • SMILES: BrC1C=C(C=C(C=1S(N)(=O)=O)F)F

Computed Properties

  • Exact Mass: 270.91142g/mol
  • Monoisotopic Mass: 270.91142g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 279
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.4
  • Topological Polar Surface Area: 68.5?2

Experimental Properties

  • Melting Point: 125-126°C

2-Bromo-4,6-difluorobenzenesulfonamide Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

2-Bromo-4,6-difluorobenzenesulfonamide Pricemore >>

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2-Bromo-4,6-difluorobenzenesulfonamide; .
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Additional information on 2-Bromo-4,6-difluorobenzenesulfonamide

Comprehensive Overview of 2-Bromo-4,6-difluorobenzenesulfonamide (CAS No. 951624-79-6)

2-Bromo-4,6-difluorobenzenesulfonamide (CAS No. 951624-79-6) is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. Its unique molecular structure, featuring bromine and fluorine substituents, makes it a valuable intermediate in the synthesis of bioactive molecules. Researchers and industry professionals frequently search for this compound due to its relevance in drug discovery, medicinal chemistry, and crop protection applications. The growing demand for fluorinated compounds in modern chemistry further underscores its importance.

The compound’s sulfonamide group is a key functional moiety, often associated with antimicrobial and anti-inflammatory properties. This has led to increased interest in 2-Bromo-4,6-difluorobenzenesulfonamide as a building block for developing novel therapeutics. Recent trends in AI-driven drug design and high-throughput screening have also highlighted its potential, as computational models increasingly prioritize halogenated and fluorinated scaffolds for optimized binding affinity and metabolic stability.

From a synthetic perspective, CAS No. 951624-79-6 is often employed in cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, to construct complex aromatic systems. Its bromo substituent acts as a versatile handle for further functionalization, while the difluoro pattern enhances electronic properties, making it a preferred choice for material science applications. Questions like "How to synthesize 2-Bromo-4,6-difluorobenzenesulfonamide?" or "What are the applications of fluorinated sulfonamides?" are commonly explored in academic and industrial forums.

Environmental and regulatory considerations are also critical when discussing 2-Bromo-4,6-difluorobenzenesulfonamide. With the rise of green chemistry initiatives, researchers are investigating sustainable methods to produce such compounds with minimal waste. Searches for "eco-friendly synthesis of halogenated sulfonamides" reflect this shift. Additionally, the compound’s stability and solubility profile are frequently analyzed to ensure compatibility with large-scale manufacturing processes.

In summary, 2-Bromo-4,6-difluorobenzenesulfonamide (CAS No. 951624-79-6) is a multifaceted compound bridging pharmaceutical innovation, agrochemical development, and advanced material design. Its role in cutting-edge research and alignment with global trends like sustainable chemistry and AI-aided molecular discovery ensures its continued relevance. For those seeking detailed protocols or commercial sources, keywords such as "buy 2-Bromo-4,6-difluorobenzenesulfonamide" or "CAS 951624-79-6 suppliers" are frequently queried across scientific databases and search engines.

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