Cas no 948292-94-2 (4-Amino-6,7-dichloroquinoline)

4-Amino-6,7-dichloroquinoline is a halogenated quinoline derivative with significant utility in organic synthesis and pharmaceutical research. Its dichloro-substituted quinoline core enhances reactivity, making it a valuable intermediate for constructing complex heterocyclic compounds. The amino group at the 4-position provides a versatile handle for further functionalization, enabling applications in medicinal chemistry, particularly in the development of bioactive molecules. This compound exhibits stability under standard conditions, ensuring reliable performance in synthetic workflows. Its structural features make it particularly useful in the synthesis of quinoline-based scaffolds for potential therapeutic agents, including antimicrobial and anticancer candidates. High purity grades are available to meet rigorous research and industrial requirements.
4-Amino-6,7-dichloroquinoline structure
4-Amino-6,7-dichloroquinoline structure
Product Name:4-Amino-6,7-dichloroquinoline
CAS No:948292-94-2
MF:C9H6Cl2N2
MW:213.063339710236
MDL:MFCD08063229
CID:875054
PubChem ID:17039853
Update Time:2025-08-02

4-Amino-6,7-dichloroquinoline Chemical and Physical Properties

Names and Identifiers

    • 6,7-dichloroquinolin-4-amine
    • 4-Amino-6,7-dichloroquinoline
    • AB43479
    • DTXSID90589036
    • 948292-94-2
    • CS-0335941
    • MFCD08063229
    • MDL: MFCD08063229
    • Inchi: 1S/C9H6Cl2N2/c10-6-3-5-8(12)1-2-13-9(5)4-7(6)11/h1-4H,(H2,12,13)
    • InChI Key: ZVBRYIQQZDIPRV-UHFFFAOYSA-N
    • SMILES: ClC1C(=CC2C(C=1)=C(C=CN=2)N)Cl

Computed Properties

  • Exact Mass: 211.99100
  • Monoisotopic Mass: 211.9908036g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 0
  • Complexity: 189
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 38.9?2

Experimental Properties

  • PSA: 38.91000
  • LogP: 3.70500

4-Amino-6,7-dichloroquinoline Security Information

  • Hazard Category Code: 41
  • Safety Instruction: 26-39

4-Amino-6,7-dichloroquinoline Pricemore >>

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Additional information on 4-Amino-6,7-dichloroquinoline

Comprehensive Overview of 4-Amino-6,7-dichloroquinoline (CAS No. 948292-94-2): Properties, Applications, and Research Insights

4-Amino-6,7-dichloroquinoline (CAS No. 948292-94-2) is a specialized heterocyclic compound that has garnered significant attention in pharmaceutical and materials science research. This chlorinated quinoline derivative is characterized by its unique molecular structure, featuring an amino group at the 4-position and chlorine atoms at the 6- and 7-positions. Such structural attributes make it a valuable intermediate in the synthesis of bioactive molecules and functional materials.

Researchers have explored the potential of 4-Amino-6,7-dichloroquinoline in drug discovery, particularly in the development of kinase inhibitors and antimicrobial agents. Its quinoline scaffold is known to interact with biological targets, making it a promising candidate for therapeutic applications. Recent studies highlight its role in modulating enzyme activity, which aligns with the growing interest in targeted drug delivery systems and precision medicine.

In addition to its pharmaceutical relevance, CAS No. 948292-94-2 has been investigated for its optical and electronic properties. The compound's conjugated system and electron-rich nitrogen atom contribute to its potential use in organic semiconductors and luminescent materials. This aligns with the surge in demand for advanced materials in renewable energy technologies, such as organic photovoltaics (OPVs) and light-emitting diodes (LEDs).

The synthesis of 4-Amino-6,7-dichloroquinoline typically involves multi-step reactions, including chlorination and amination processes. Optimization of these synthetic routes is a key focus area, as it impacts the compound's purity and yield—critical factors for industrial-scale production. Analytical techniques like high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) are employed to ensure quality control.

Environmental and safety considerations are paramount when handling chlorinated quinoline derivatives. While the compound is not classified as hazardous under standard regulations, proper laboratory practices, including the use of personal protective equipment (PPE) and adequate ventilation, are recommended. This reflects the broader industry trend toward green chemistry and sustainable synthesis methods.

Market trends indicate a rising demand for high-purity specialty chemicals, driven by advancements in biotechnology and electronics. 4-Amino-6,7-dichloroquinoline is positioned to benefit from this trend, given its versatility and applicability across multiple sectors. Suppliers and manufacturers are increasingly focusing on scalable production techniques to meet the needs of research institutions and industrial partners.

In summary, 4-Amino-6,7-dichloroquinoline (CAS No. 948292-94-2) represents a compelling case study in the intersection of chemistry, biology, and materials science. Its structural features and functional groups offer diverse opportunities for innovation, particularly in fields prioritizing molecular design and functional material development. As research continues to uncover new applications, this compound is likely to remain a focal point in scientific and industrial discussions.

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