Cas no 946260-11-3 (N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide)
N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide Chemical and Physical Properties
Names and Identifiers
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- Benzenesulfonamide, N-[4-(1,1-dioxido-2-isothiazolidinyl)phenyl]-2,5-dimethyl-
- N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide
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- Inchi: 1S/C17H20N2O4S2/c1-13-4-5-14(2)17(12-13)25(22,23)18-15-6-8-16(9-7-15)19-10-3-11-24(19,20)21/h4-9,12,18H,3,10-11H2,1-2H3
- InChI Key: JHHUNTCGGDJPEB-UHFFFAOYSA-N
- SMILES: C1(S(NC2=CC=C(N3CCCS3(=O)=O)C=C2)(=O)=O)=CC(C)=CC=C1C
N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Life Chemicals | F2035-0036-2μmol |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 2μmol |
$57.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-5μmol |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 5μmol |
$63.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-10μmol |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 10μmol |
$69.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-20μmol |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 20μmol |
$79.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-1mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 1mg |
$54.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-2mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 2mg |
$59.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-3mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 3mg |
$63.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-4mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 4mg |
$66.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-5mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 5mg |
$69.0 | 2023-07-28 | |
| Life Chemicals | F2035-0036-10mg |
N-[4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl]-2,5-dimethylbenzene-1-sulfonamide |
946260-11-3 | 90%+ | 10mg |
$79.0 | 2023-07-28 |
N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide Related Literature
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Xiang Liu,Qian Sun,A. B. Djuri?i?,Maohai Xie,Baohu Dai,Jinyao Tang,Charles Surya,Changzhong Liao,Kaimin Shih RSC Adv., 2015,5, 100783-100789
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R. M. Pemberton,J. P. Hart,T. T. Mottram Analyst, 2001,126, 1866-1871
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Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
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Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
Additional information on N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide
Introduction to N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide (CAS No. 946260-11-3)
N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide is a sophisticated organic compound that has garnered significant attention in the field of pharmaceutical chemistry and bioorganic synthesis. This compound, identified by its CAS number 946260-11-3, represents a novel molecular entity with a complex structural framework that includes a phenyl ring substituted with a sulfonamide group and an additional thiazolidine moiety. The presence of these functional groups suggests potential biological activity and makes this compound a subject of intense interest for researchers exploring new therapeutic agents.
The structural composition of N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide is characterized by its aromatic system and the presence of heterocyclic rings. The sulfonamide group (-SO?NH?) is known for its versatility in medicinal chemistry, often serving as a pharmacophore in drug design due to its ability to form hydrogen bonds and interact with biological targets. The thiazolidine ring, on the other hand, is a sulfur-containing heterocycle that has been widely studied for its role in various bioactive molecules.
Recent advancements in computational chemistry and molecular modeling have enabled researchers to predict the biological properties of such complex molecules with greater accuracy. The combination of the phenyl ring, sulfonamide group, and thiazolidine moiety in N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide suggests potential interactions with enzymes and receptors involved in critical biological pathways. This has prompted investigations into its possible applications as an intermediate in the synthesis of novel drugs targeting conditions such as inflammation, cancer, and infectious diseases.
In the realm of drug discovery, the development of new scaffolds is essential for overcoming resistance mechanisms and improving therapeutic efficacy. The unique structural features of N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide make it an attractive candidate for further exploration. Researchers have been particularly interested in how the arrangement of these functional groups can influence the compound's solubility, bioavailability, and metabolic stability—key factors in determining its suitability for clinical use.
The synthesis of this compound involves multi-step organic reactions that require precise control over reaction conditions to ensure high yield and purity. Advanced synthetic techniques such as palladium-catalyzed cross-coupling reactions have been employed to construct the complex framework efficiently. The use of these methodologies not only enhances the synthetic route but also opens up possibilities for introducing additional modifications to fine-tune the biological activity of the molecule.
One area of active research is the exploration of derivatives of N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-yl)phenyl-2,5-dimethylbenzene-1-sulfonamide that exhibit enhanced potency or selectivity. By systematically varying substituents on the phenyl ring or modifying the thiazolidine moiety, chemists aim to identify analogs with improved pharmacological profiles. Such efforts are supported by high-throughput screening technologies that allow for rapid testing of large libraries of compounds.
The role of computational methods in drug discovery cannot be overstated. Molecular docking studies have been instrumental in understanding how N-4-(1,1-dioxo-1lambda6,2-thiazolidin-2-y)]phenyl)-2^methylbenzene^sulfonamide interacts with target proteins. These studies provide insights into binding affinities and potential side effects before experimental validation is undertaken. This integration of computational biology with synthetic chemistry has accelerated the pace at which new drug candidates are identified.
In conclusion,N^-4^-((^11^-dioxo^-^-^lambda6^^^)-thiaziol^^^-d^^^-^nyl)^)-pheny]-^(-^methyl^^)-^(-^dimethyl^^)-b^nene^-sulfonamid^^e represents a promising lead in pharmaceutical research due to its intricate structure and potential biological activity。Ongoing studies aimed at optimizing its synthesis and evaluating its pharmacological properties hold great promise for advancing therapeutic strategies against various diseases。As our understanding of molecular interactions continues to grow,compounds like this one will play a crucial role in shaping the future of medicine。
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