• 1. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 2. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 3. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
• 4. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 5. Excimer and exciplex formation in a pair of bright phosphorescent isomers constructed from Cu3(pyrazolate)3 and Cu3I3 coordination luminophores?
  Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459

Comprehensive Overview of 3-Bromo-7-iodo-1H-indazole (CAS No. 945761-95-5): Properties, Applications, and Research Insights

3-Bromo-7-iodo-1H-indazole (CAS No. 945761-95-5) is a halogen-substituted indazole derivative that has garnered significant attention in pharmaceutical and material science research. This compound, characterized by its bromo and iodo functional groups, serves as a versatile intermediate in organic synthesis and drug discovery. Its molecular structure, combining a heterocyclic indazole core with halogen atoms, makes it a valuable building block for designing novel bioactive molecules. Researchers often explore its potential in kinase inhibition, cancer therapeutics, and PET imaging probes, aligning with current trends in precision medicine and targeted therapy.

The growing demand for halogenated indazoles like 3-Bromo-7-iodo-1H-indazole reflects broader industry shifts toward highly functionalized heterocycles. These compounds are pivotal in addressing challenges such as drug resistance and selective binding affinity—topics frequently searched in academic and industrial databases. With its CAS No. 945761-95-5, this compound is cataloged in major chemical inventories, facilitating traceability for regulatory compliance and supply chain transparency. Its stability under controlled conditions and compatibility with cross-coupling reactions (e.g., Suzuki-Miyaura or Buchwald-Hartwig) further enhance its utility in modern synthetic workflows.

Recent studies highlight the role of 3-Bromo-7-iodo-1H-indazole in developing small-molecule inhibitors for neurodegenerative diseases, a hotspot in 2024 biomedical research. Searches for "indazole derivatives in Alzheimer’s" or "iodo-substituted kinase modulators" underscore its relevance. The compound’s dual halogenation offers unique reactivity patterns, enabling selective modifications at either the bromo or iodo position—a feature exploited in parallel synthesis and combinatorial chemistry. Analytical techniques like HPLC-MS and NMR are routinely employed to validate its purity, a critical factor given its applications in high-throughput screening.

From an industrial perspective, 945761-95-5 is often procured for custom synthesis and contract research organizations (CROs). Its inclusion in fragment-based drug design (FBDD) libraries aligns with the rise of AI-driven molecular docking, another trending topic. Environmental and safety profiles of halogenated compounds are also under scrutiny, prompting innovations in green chemistry alternatives—a nuance worth noting for sustainable R&D. As patent filings citing 3-Bromo-7-iodo-1H-indazole increase, its commercial and academic value continues to rise, particularly in oncology and central nervous system (CNS) drug pipelines.

In summary, 3-Bromo-7-iodo-1H-indazole (CAS No. 945761-95-5) exemplifies the intersection of structural diversity and functional adaptability in medicinal chemistry. Its applications span from radiopharmaceuticals to agrochemicals, resonating with global efforts to tackle complex diseases and optimize chemical processes. For researchers querying "buy 3-Bromo-7-iodo-indazole" or "indazole synthesis protocols," this compound remains a cornerstone of innovation, backed by rigorous scientific validation and evolving market demand.

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