• 1. Alt-proteins: A promising future
• 2. An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement?
  Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
• 3. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 4. An arsenic trioxide nanoparticle prodrug (ATONP) potentiates a therapeutic effect on an aggressive hepatocellular carcinoma model via enhancement of intratumoral arsenic accumulation and disturbance of the tumor microenvironment?
  Xin Fu,Qing-rong Liang,Rong-guang Luo,Yan-shu Li,Xiao-ping Xiao,Lu-lu Yu,Wen-zhe Shan,Guang-qin Fan J. Mater. Chem. B, 2019,7, 3088-3099
• 5. Acentric and chiral heterometallic inorganic–organic hybrid frameworks mediated by alkali or alkaline earth ions: synthesis and NLO properties
  Huabin Zhang,Shaowu Du CrystEngComm, 2014,16, 4059-4068

Introduction to 2-(azepan-1-yl)pyridin-3-amine (CAS No. 94520-29-3) in Modern Chemical and Pharmaceutical Research

2-(azepan-1-yl)pyridin-3-amine, identified by the chemical identifier CAS No. 94520-29-3, is a compound of significant interest in the realm of pharmaceutical chemistry and medicinal biology. This molecule, featuring a pyridine ring linked to an azepane moiety through an amine functional group, has garnered attention due to its structural versatility and potential biological activity. The integration of these heterocyclic structures not only enhances the compound's solubility and metabolic stability but also opens avenues for exploring novel pharmacological interactions.

The azepan-1-yl substituent in 2-(azepan-1-yl)pyridin-3-amine contributes to the compound's overall conformational flexibility, which is a critical factor in drug design. Azepane derivatives are known for their ability to mimic the natural conformation of biological targets, thereby facilitating tighter binding and improved efficacy. This structural motif has been widely explored in the development of central nervous system (CNS) drugs, where precise molecular fitting is essential for therapeutic outcomes.

Recent advancements in computational chemistry have enabled more sophisticated modeling of 2-(azepan-1-yl)pyridin-3-amine, allowing researchers to predict its interactions with biological targets with greater accuracy. Studies indicate that the compound exhibits promising binding affinity to certain enzyme receptors, making it a candidate for further investigation in therapeutic applications such as neurodegenerative diseases and inflammatory disorders. The pyridine ring, a common pharmacophore in medicinal chemistry, further enhances the compound's potential by providing a hydrogen bond acceptor site that can interact with polar regions of biological targets.

In vitro studies have begun to unravel the pharmacological profile of 2-(azepan-1-yl)pyridin-3-amine, revealing its potential as an inhibitor of specific kinases and transcription factors. These kinases play pivotal roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. By modulating their activity, 2-(azepan-1-yl)pyridin-3-amine could offer therapeutic benefits in conditions where dysregulation of these pathways is implicated.

The synthesis of 2-(azepan-1-yl)pyridin-3-amine presents unique challenges due to the complexity of its dual heterocyclic core. However, modern synthetic methodologies have made significant strides in optimizing production routes, ensuring high yields and purity. Advances in catalytic processes have enabled more efficient transformations, reducing the need for hazardous reagents and minimizing waste generation—a critical consideration in sustainable pharmaceutical development.

One particularly intriguing aspect of 2-(azepan-1-yl)pyridin-3-amine is its potential for derivatization. By introducing additional functional groups or modifying existing ones, researchers can fine-tune its pharmacological properties to target specific disease mechanisms. This flexibility underscores the compound's value as a scaffold for drug discovery programs aimed at addressing unmet medical needs.

The growing interest in 2-(azepan-1-yl)pyridin-3-amines is reflected in the increasing number of patents and publications detailing their synthesis and applications. Companies specializing in custom synthesis are increasingly offering tailored solutions for researchers seeking this compound or its derivatives for preclinical and clinical studies. This trend underscores the commercial viability and scientific relevance of molecules like 2-(azepan-1-yloxy)pyridinamides, which share structural similarities and may exhibit comparable biological activities.

As research progresses, collaborations between academic institutions and pharmaceutical companies will be crucial in translating laboratory findings into viable therapeutic agents. The interdisciplinary nature of modern drug discovery requires expertise from chemists, biologists, pharmacologists, and computational scientists to fully exploit the potential of compounds like 2-(azepanamino)pyridines.

The regulatory landscape for novel pharmaceuticals continues to evolve, emphasizing safety and efficacy through rigorous preclinical testing. compounds such as CAS No 94520 29 3 must undergo stringent evaluation before advancing to human trials. However, the promise they hold for addressing complex diseases makes their development a worthwhile endeavor.

In conclusion,(azepane 1 yl) pyridine 3 amine represents a compelling subject of study within chemical biology and pharmaceutical chemistry. Its unique structural features combined with emerging research findings position it as a valuable candidate for further exploration into new therapeutic modalities.

• 55403-29-7(6-piperidin-1-ylpyridin-3-amine)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)