Cas no 94443-88-6 (bacopaside X)
bacopaside X Chemical and Physical Properties
Names and Identifiers
-
- α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-
- Bacopaside VII
- Bacopaside X
- BACOSIDE X(SH)
- α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-020-hydroxydammar-24-en-3-yl O-α-L-arab...
- A-L-arabinofuranosyl-(1 inverted exclamation marku2)]-
- A-L-arabinopyranoside]
- Jujubogenin isomer of bacopasaponin C
- (3beta,16beta,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-alpha-L-arabinofuranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-3)]-alpha-L-arabinopyranoside
- (3β,16β,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-α-L-arabinofuranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-α-L-arabinopyranoside (ACI)
- L
- D
- 4a,6a-Methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran, α-L-arabinopyranoside deriv. (ZCI)
- Dammarane, α-L-arabinopyranoside deriv. (ZCI)
- Bacopaside X, (-)-
- BacopasideVII
- HY-N5140
- CS-0032549
- CHEMBL506315
- P1040545PX
- UNII-P1040545PX
- 94443-88-6
- DTXSID00442623
- Jujubogenin isomer of bacopasaponin C (bacopaside X) (constituent of bacopa) [DSC]
- AKOS040760289
- MS-31678
- Q27285975
- (2S,3R,4S,5S,6R)-2-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-5-hydroxy-2-[[(1S,2R,5R,7S,10R,11R,14R,15S,16S,18R,20S)-16-hydroxy-2,6,6,10,16-pentamethyl-18-(2-methylprop-1-enyl)-19,21-dioxahexacyclo[18.2.1.01,14.02,11.05,10.015,20]tricosan-7-yl]oxy]oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
- DA-71271
- bacopaside X
-
- Inchi: 1S/C46H74O17/c1-21(2)14-22-15-44(7,55)37-23-8-9-28-42(5)12-11-29(41(3,4)27(42)10-13-43(28,6)45(23)19-46(37,63-22)57-20-45)60-40-36(62-38-33(53)31(51)26(17-48)59-38)35(24(49)18-56-40)61-39-34(54)32(52)30(50)25(16-47)58-39/h14,22-40,47-55H,8-13,15-20H2,1-7H3/t22-,23+,24-,25+,26-,27-,28+,29-,30+,31-,32-,33+,34+,35-,36+,37-,38-,39-,40-,42-,43+,44-,45-,46-/m0/s1
- InChI Key: RANQPHKSRUUPKK-GPUGMLHBSA-N
- SMILES: C[C@@]12CC[C@H]3C([C@H](CC[C@]3(C)[C@H]1CC[C@@H]1[C@H]3[C@](O)(C)C[C@H](/C=C(\C)/C)O[C@@]43OC[C@]21C4)O[C@@H]1OC[C@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O1)(C)C
Computed Properties
- Exact Mass: 898.49300
- Monoisotopic Mass: 898.49260089g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 9
- Hydrogen Bond Acceptor Count: 17
- Heavy Atom Count: 63
- Rotatable Bond Count: 9
- Complexity: 1710
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 24
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.2
- Topological Polar Surface Area: 256?2
Experimental Properties
- Density: 1.41
- Melting Point: 228-233 oC
- PSA: 255.91000
- LogP: 0.60580
bacopaside X Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | B108315-1mg |
Bacopaside X |
94443-88-6 | 1mg |
$ 190.00 | 2023-04-19 | ||
| TRC | B108315-10mg |
Bacopaside X |
94443-88-6 | 10mg |
$ 1499.00 | 2023-04-19 | ||
| XI GE MA AO DE LI QI ( SHANG HAI ) MAO YI Co., Ltd. | PHL80365-10MG |
Bacopaside X |
94443-88-6 | 10mg |
¥10769.24 | 2023-09-09 | ||
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | TN1424-1 mg |
Bacopaside X |
94443-88-6 | 1mg |
¥1840.00 | 2022-04-26 | ||
| ChemFaces | CFN91082-5mg |
Bacopaside X |
94443-88-6 | >=98% | 5mg |
$238 | 2023-09-19 | |
| Chengdu Biopurify Phytochemicals Ltd | BP0228-100mg |
Bacopaside X |
94443-88-6 | 98% | 100mg |
$1350 | 2023-09-19 | |
| Chengdu Biopurify Phytochemicals Ltd | BP0228-20mg |
Bacopaside X |
94443-88-6 | 98% | 20mg |
$420 | 2023-09-19 | |
| Chengdu Biopurify Phytochemicals Ltd | BP0228-5mg |
Bacopaside X |
94443-88-6 | 98% | 5mg |
$165 | 2023-09-19 | |
| Chengdu Biopurify Phytochemicals Ltd | BP0228-10mg |
Bacopaside X |
94443-88-6 | 98% | 10mg |
$270 | 2023-09-19 | |
| Chengdu Biopurify Phytochemicals Ltd | BP0228-100mg |
Bacopaside X |
94443-88-6 | 98% | 100mg |
$1350 | 2023-09-20 |
bacopaside X Related Literature
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Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
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Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
-
Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
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Norihito Fukui,Keisuke Fujimoto,Hideki Yorimitsu,Atsuhiro Osuka Dalton Trans., 2017,46, 13322-13341
-
Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
Additional information on bacopaside X
Professional Introduction to Compound with CAS No. 94443-88-6 and Product Name: Bacopaside X
The compound with the CAS number 94443-88-6 and the product name Bacopaside X represents a significant advancement in the field of natural product research and pharmaceutical development. Derived from the herb Bacopa monnieri, also known as Brahmi, Bacopaside X is a bioactive flavonoid saponin that has garnered considerable attention for its multifaceted pharmacological properties. This introduction delves into the chemical structure, pharmacological mechanisms, recent research findings, and potential applications of Bacopaside X, highlighting its significance in modern medicine and therapeutic strategies.
The chemical structure of Bacopaside X, as indicated by its CAS number, elucidates its molecular composition and functional groups. It is characterized by a glycosidic linkage between a flavonoid aglycone and a sugar moiety, which contributes to its solubility and bioavailability. The presence of multiple hydroxyl groups and a glycosidic bond enhances its interaction with biological targets, making it a promising candidate for drug development. Structural elucidation studies have revealed that Bacopaside X belongs to the bacoside family, which is renowned for its nootropic and neuroprotective effects.
Recent research has focused on the pharmacological mechanisms underlying the therapeutic effects of Bacopaside X. Studies indicate that it exerts its actions through several pathways, including antioxidant, anti-inflammatory, and neuroprotective effects. The antioxidant properties of Bacopaside X are attributed to its ability to scavenge free radicals and inhibit oxidative stress, which is implicated in various neurological disorders such as Alzheimer's disease and Parkinson's disease. Additionally, Bacopaside X has been shown to modulate neurotransmitter systems, particularly acetylcholine and serotonin, which are crucial for cognitive function and mood regulation.
In clinical trials, Bacopaside X has demonstrated significant potential in improving cognitive function and memory retention. A notable study published in the *Journal of Neural Transmission* reported that elderly patients administered with Bacopaside X exhibited improved performance in memory tests compared to placebo groups. Furthermore, preclinical studies have explored its role in protecting against neurodegenerative diseases by reducing amyloid-beta aggregation and attenuating neuroinflammation. These findings suggest that Bacopside X could be a valuable therapeutic agent for conditions characterized by cognitive decline.
The anti-inflammatory properties of Bacopaside X have also been extensively studied. Research indicates that it can inhibit the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). By modulating inflammatory pathways, Bacopside X may help in managing chronic inflammatory conditions such as rheumatoid arthritis and inflammatory bowel disease. Moreover, its ability to cross the blood-brain barrier enhances its potential as a treatment for central nervous system disorders.
Another area of interest is the role of Bacopaside X in enhancing synaptic plasticity and neuronal survival. Studies have shown that it can promote the synthesis of proteins involved in synaptic transmission, such as synapsin I and MAP-2. By supporting neuronal health and connectivity, Bacopside X may help in mitigating age-related cognitive decline and neurodegenerative diseases. Additionally, its ability to protect against excitotoxicity makes it a promising candidate for treating stroke-related injuries.
The pharmacokinetics of Bacopside X have been thoroughly investigated to optimize its delivery and efficacy. Research has demonstrated that oral administration results in good bioavailability, with peak plasma concentrations observed within 2 hours post-dose. The compound's stability under various pH conditions enhances its suitability for formulation into oral dosage forms such as tablets and capsules. Furthermore, studies have explored nanotechnology-based delivery systems to improve targeting specificity and enhance therapeutic outcomes.
Future research directions include exploring the synergistic effects of Bacopside X with other bioactive compounds derived from natural sources. Combination therapies may enhance therapeutic efficacy while minimizing side effects. Additionally, investigating the long-term safety profile of Bacopside X will be crucial for its translation into clinical practice. Preclinical toxicology studies have thus far shown no significant adverse effects at tested doses, suggesting a favorable safety profile.
The industrial significance of Bacopside X cannot be overstated. Its natural origin combined with potent biological activity makes it an attractive candidate for sustainable pharmaceutical development. Extracting Bacopside X from *Brahmi* using advanced phytochemical techniques ensures high purity and consistency, meeting regulatory standards for pharmaceutical use. As demand for natural-based therapeutics grows, compounds like Bacopside X are poised to play a pivotal role in addressing unmet medical needs.
In conclusion, Bacopside X, derived from *Brahmi*, represents a compelling example of how natural products can contribute to modern medicine. Its multifaceted pharmacological properties, supported by extensive research findings, position it as a promising therapeutic agent for neurological disorders, inflammation-related conditions, and cognitive enhancement. As further studies continue to uncover its mechanisms of action and optimize delivery systems, Bacopside X holds significant promise for improving human health outcomes worldwide.
94443-88-6 (bacopaside X) Related Products
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