Cas no 943026-51-5 (5,7-difluoro-1H-Indole-2-carboxaldehyde)
5,7-Difluoro-1H-Indole-2-carboxaldehyde is a fluorinated indole derivative with significant utility in organic synthesis and pharmaceutical research. The presence of fluorine atoms at the 5 and 7 positions enhances its reactivity and electronic properties, making it a valuable intermediate for constructing complex heterocyclic compounds. Its aldehyde functional group allows for versatile derivatization, enabling applications in medicinal chemistry, particularly in the development of bioactive molecules. The compound's structural features contribute to improved metabolic stability and binding affinity in drug design. It is commonly employed in cross-coupling reactions, nucleophilic additions, and as a precursor for indole-based scaffolds. Suitable for controlled environments, it requires handling under inert conditions due to its sensitivity.
943026-51-5 structure
Product Name:5,7-difluoro-1H-Indole-2-carboxaldehyde
CAS No:943026-51-5
MF:C9H5F2NO
MW:181.138909101486
MDL:MFCD24611698
CID:1122406
PubChem ID:87433044
Update Time:2025-05-28
5,7-difluoro-1H-Indole-2-carboxaldehyde Chemical and Physical Properties
Names and Identifiers
-
- 5,7-difluoro-1H-Indole-2-carboxaldehyde
- 943026-51-5
- SCHEMBL2770272
- 5,7-difluoro-1h-indole-2-carbaldehyde
-
- MDL: MFCD24611698
- Inchi: 1S/C9H5F2NO/c10-6-1-5-2-7(4-13)12-9(5)8(11)3-6/h1-4,12H
- InChI Key: SNUIGNIPNQUELN-UHFFFAOYSA-N
- SMILES: FC1=CC(=CC2C=C(C=O)NC=21)F
Computed Properties
- Exact Mass: 181.03392011g/mol
- Monoisotopic Mass: 181.03392011g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 212
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2
- Topological Polar Surface Area: 32.9?2
5,7-difluoro-1H-Indole-2-carboxaldehyde Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Matrix Scientific | 223302-1g |
5,7-Difluoro-1H-indole-2-carbaldehyde, 95% min |
943026-51-5 | 95% | 1g |
$1680.00 | 2023-09-09 | |
| Matrix Scientific | 223302-5g |
5,7-Difluoro-1H-indole-2-carbaldehyde, 95% min |
943026-51-5 | 95% | 5g |
$4830.00 | 2023-09-09 |
5,7-difluoro-1H-Indole-2-carboxaldehyde Related Literature
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
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Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
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Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
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