Cas no 941940-10-9 (N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide)

N-2-(Dimethylamino)-2-phenylethylnaphthalene-2-carboxamide is a synthetic organic compound featuring a naphthalene core linked to a phenylethylamine-derived carboxamide moiety with a dimethylamino substituent. This structure confers potential utility in pharmaceutical and biochemical research, particularly as an intermediate or ligand due to its aromatic and tertiary amine functionalities. The compound’s rigid naphthalene scaffold may enhance binding affinity in receptor studies, while the dimethylamino group offers basicity for solubility modulation or interaction with biological targets. Its well-defined molecular architecture makes it suitable for structure-activity relationship investigations or as a precursor in medicinal chemistry applications. Proper handling and storage are recommended due to its synthetic complexity.
N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide structure
941940-10-9 structure
Product Name:N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide
CAS No:941940-10-9
MF:C21H22N2O
MW:318.4122
CID:5460328
Update Time:2025-05-30

N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide Chemical and Physical Properties

Names and Identifiers

    • N-[2-(dimethylamino)-2-phenylethyl]naphthalene-2-carboxamide
    • N-(2-(dimethylamino)-2-phenylethyl)-2-naphthamide
    • N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide
    • Inchi: 1S/C21H22N2O/c1-23(2)20(17-9-4-3-5-10-17)15-22-21(24)19-13-12-16-8-6-7-11-18(16)14-19/h3-14,20H,15H2,1-2H3,(H,22,24)
    • InChI Key: VBJZIFQVVPNNAX-UHFFFAOYSA-N
    • SMILES: O=C(C1C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C2C=1[H])N([H])C([H])([H])C([H])(C1C([H])=C([H])C([H])=C([H])C=1[H])N(C([H])([H])[H])C([H])([H])[H]

Computed Properties

  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 24
  • Rotatable Bond Count: 5
  • Complexity: 403
  • XLogP3: 4
  • Topological Polar Surface Area: 32.299

N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide Pricemore >>

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N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide Related Literature

Additional information on N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide

Recent Advances in the Study of N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide (CAS: 941940-10-9)

The compound N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide (CAS: 941940-10-9) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its unique structural features, has shown promising potential in various therapeutic applications. Recent studies have focused on elucidating its pharmacological properties, mechanism of action, and potential clinical applications. This research brief aims to provide a comprehensive overview of the latest findings related to this compound.

One of the key areas of investigation has been the compound's interaction with specific biological targets. Preliminary studies suggest that N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide exhibits high affinity for certain receptor types, which may underlie its therapeutic effects. Researchers have employed advanced techniques such as X-ray crystallography and molecular docking simulations to map the binding interactions at the atomic level. These studies have provided valuable insights into the structural determinants of its activity.

In addition to its binding properties, recent research has explored the compound's pharmacokinetic profile. Animal studies have demonstrated favorable absorption and distribution characteristics, with particular attention paid to its ability to cross the blood-brain barrier. This property makes it a candidate for central nervous system (CNS) targeted therapies. However, challenges remain in optimizing its metabolic stability and minimizing potential off-target effects.

The therapeutic potential of N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide has been investigated in several disease models. Notably, studies in neurodegenerative disorders have shown promising results, with the compound demonstrating neuroprotective effects in vitro and in vivo. Researchers have also explored its application in pain management, where it appears to modulate specific pain pathways with potentially fewer side effects than current treatments.

From a synthetic chemistry perspective, recent work has focused on developing more efficient routes to produce N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide. Novel synthetic methodologies have been reported that improve yield and purity while reducing environmental impact. These advances are crucial for scaling up production for potential clinical trials and eventual therapeutic use.

Despite these promising developments, several questions remain unanswered. Current research efforts are directed toward understanding the long-term safety profile of the compound and its potential interactions with other medications. Additionally, researchers are working to identify structural analogs that might offer improved therapeutic indices. The coming years are likely to see increased clinical translation of these findings, potentially leading to new treatment options for various medical conditions.

In conclusion, N-2-(dimethylamino)-2-phenylethylnaphthalene-2-carboxamide (CAS: 941940-10-9) represents an exciting area of research in chemical biology and pharmaceutical development. The compound's unique properties and promising preclinical results warrant continued investigation. As research progresses, this molecule may emerge as a valuable tool for understanding biological systems and developing novel therapeutics.

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