• 1. Exceptionally high temperature spin crossover in amide-functionalised 2,6-bis(pyrazol-1-yl)pyridine iron(ii) complex revealed by variable temperature Raman spectroscopy and single crystal X-ray diffraction?
  Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
• 2. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 3. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
• 4. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 5. Fe3O4 nanoparticle chains with N-doped carbon coating: magnetotactic bacteria assisted synthesis and high-rate lithium storage?
  Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962

Methyl 3,5-Dibromo-4-Chloro-2-Hydroxybenzoate: A Comprehensive Overview

Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate, also known by its CAS number 941294-24-2, is a compound of significant interest in the fields of organic chemistry and materials science. This compound is characterized by its unique structure, which includes a benzoate ester functional group and multiple halogen substituents. The presence of bromine and chlorine atoms at specific positions on the aromatic ring imparts distinctive chemical and physical properties to the molecule.

The synthesis of Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate typically involves multi-step reactions, often starting from hydroxylbenzoic acid derivatives. The introduction of bromine and chlorine substituents is achieved through electrophilic aromatic substitution reactions, which are carefully controlled to ensure regioselectivity. Recent advancements in catalytic systems and reaction conditions have improved the yield and purity of this compound, making it more accessible for research and industrial applications.

One of the most notable applications of Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate is in the field of polymer science. The compound serves as a versatile building block for the synthesis of advanced polymers with tailored properties. For instance, researchers have utilized this compound to develop high-performance thermoplastics that exhibit excellent thermal stability and mechanical strength. These materials find applications in aerospace, automotive industries, and electronic devices where durability under extreme conditions is critical.

In addition to polymer applications, Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate has shown promise in pharmaceutical research. The compound's structure allows for the creation of bioactive molecules with potential therapeutic effects. Recent studies have explored its role as a precursor for anti-inflammatory agents and antioxidants. Its ability to undergo various chemical transformations makes it a valuable intermediate in drug discovery pipelines.

The environmental impact of Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate has also been a subject of recent investigations. Researchers have assessed its biodegradability and toxicity under various conditions. Findings indicate that while the compound exhibits moderate persistence in certain environments, it does not pose significant risks to aquatic life at typical exposure levels. These studies contribute to the development of sustainable practices for handling and disposing of such chemicals.

From a structural perspective, the molecule's symmetry and electronic distribution play a crucial role in its reactivity. The hydroxyl group at position 2 facilitates hydrogen bonding, which influences solubility and intermolecular interactions. Meanwhile, the bromine and chlorine atoms introduce electron-withdrawing effects, enhancing the compound's electrophilicity and reactivity in certain reactions.

In conclusion, Methyl 3,5-dibromo-4-chloro-2-hydroxybenzoate (CAS No. 941294-24-2) stands out as a multifaceted compound with diverse applications across various scientific disciplines. Its unique chemical properties make it an invaluable tool in both academic research and industrial innovation. As ongoing studies continue to uncover new potentials for this compound, its significance in modern chemistry is expected to grow further.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)