Cas no 939398-71-7 ((1r,2r)-2-fluorocyclopentan-1-amine)

(1r,2r)-2-Fluorocyclopentan-1-amine is a chiral fluorinated amine with a cyclopentane backbone, offering distinct stereochemical and electronic properties due to the fluorine substituent. The trans-configuration (1r,2r) ensures high stereoselectivity, making it valuable in asymmetric synthesis and pharmaceutical intermediates. The fluorine atom enhances metabolic stability and binding affinity in bioactive molecules, while the amine group provides a versatile handle for further functionalization. This compound is particularly useful in medicinal chemistry for the development of enzyme inhibitors or receptor modulators. Its rigid cyclopentane structure contributes to conformational restraint, improving target specificity. Suitable for research applications requiring precise stereocontrol and fluorinated building blocks.
(1r,2r)-2-fluorocyclopentan-1-amine structure
939398-71-7 structure
Product Name:(1r,2r)-2-fluorocyclopentan-1-amine
CAS No:939398-71-7
MF:C5H10FN
MW:103.138004779816
CID:1982328
PubChem ID:53302323
Update Time:2025-10-29

(1r,2r)-2-fluorocyclopentan-1-amine Chemical and Physical Properties

Names and Identifiers

    • (1r,2r)-2-fluorocyclopentan-1-amine
    • (1R,2R)-2-Fluorocyclopentanamine Hydrochloride
    • I14-16297
    • WT971
    • (1R,2R)-2-fluorocyclopentanamine
    • SureCN757356
    • FT-0668626
    • DTXSID80693373
    • SCHEMBL757356
    • rac-(1R,2R)-2-fluorocyclopentan-1-amine
    • F1912-2823
    • AKOS006372286
    • 939398-71-7
    • (1R,2R)-rel-2-Fluorocyclopentan-1-amine
    • 921753-35-7
    • EN300-6967054
    • MDL: MFCD18632903
    • Inchi: 1S/C5H10FN/c6-4-2-1-3-5(4)7/h4-5H,1-3,7H2/t4-,5-/m1/s1
    • InChI Key: SYDPJQJXMGPZQF-RFZPGFLSSA-N
    • SMILES: F[C@@H]1CCC[C@H]1N

Computed Properties

  • Exact Mass: 103.08000
  • Monoisotopic Mass: 103.079727485Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 0
  • Complexity: 65.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.6
  • Topological Polar Surface Area: 26?2

Experimental Properties

  • PSA: 26.02000
  • LogP: 1.53600

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(1r,2r)-2-fluorocyclopentan-1-amine Production Method

(1r,2r)-2-fluorocyclopentan-1-amine Suppliers

Amadis Chemical Company Limited
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Audited Supplier Audited Supplier
(CAS:939398-71-7)(1r,2r)-2-fluorocyclopentan-1-amine
Order Number:A1094980
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 20:14
Price ($):1023.0

Additional information on (1r,2r)-2-fluorocyclopentan-1-amine

Comprehensive Overview of (1R,2R)-2-Fluorocyclopentan-1-amine (CAS No. 939398-71-7)

(1R,2R)-2-Fluorocyclopentan-1-amine is a chiral fluorinated amine compound with significant potential in pharmaceutical and agrochemical applications. Its unique stereochemistry, marked by the fluorine substitution at the 2-position of the cyclopentane ring, enhances its bioactivity and selectivity. The CAS registry number 939398-71-7 ensures precise identification in chemical databases, making it a critical reference for researchers exploring small-molecule drug candidates or enantioselective synthesis.

Recent trends highlight growing interest in fluorinated building blocks like (1R,2R)-2-Fluorocyclopentan-1-amine, driven by their role in modulating pharmacokinetic properties. Searches for "chiral amines in drug discovery" or "fluorine in medicinal chemistry" reflect this demand. The compound’s stereospecificity aligns with the industry’s focus on targeted therapies, particularly in oncology and CNS disorders, where precision is paramount.

Synthetically, 939398-71-7 serves as a versatile intermediate. Its cyclopentane backbone offers rigidity, while the amine group facilitates derivatization into amides or sulfonamides. Researchers often query "how to synthesize fluorinated cyclopentanes" or "applications of chiral amines," underscoring its relevance. Green chemistry principles are also applied to its production, addressing concerns about sustainable synthesis.

In agrochemicals, (1R,2R)-2-Fluorocyclopentan-1-amine may contribute to pesticide development, leveraging fluorine’s ability to enhance ligand-receptor interactions. Queries like "fluorine in crop protection" or "chiral auxiliaries in agriculture" mirror this niche. Regulatory scrutiny on eco-friendly pesticides further elevates its appeal.

Analytical characterization of CAS 939398-71-7 involves advanced techniques like HPLC chiral separation and NMR spectroscopy, topics frequently searched alongside "amine purity analysis." Its storage typically requires inert conditions to preserve enantiomeric integrity, a detail critical for reproducibility in lab settings.

Future directions for (1R,2R)-2-Fluorocyclopentan-1-amine include exploring biocatalytic routes or AI-driven molecular design, aligning with trends like "machine learning in chemistry." Its dual utility in life sciences and materials science ensures enduring relevance, making it a staple in innovation pipelines.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:939398-71-7)(1r,2r)-2-fluorocyclopentan-1-amine
A1094980
Purity:99%
Quantity:1g
Price ($):1023.0
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