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Comprehensive Guide to 2-(7-Bromo-1H-indol-3-yl)ethan-1-ol (CAS No. 936252-65-2): Properties, Applications, and Market Insights

2-(7-Bromo-1H-indol-3-yl)ethan-1-ol (CAS No. 936252-65-2) is a brominated indole derivative that has garnered significant attention in pharmaceutical and biochemical research. This compound, characterized by its unique indole core and hydroxyethyl side chain, serves as a versatile intermediate in organic synthesis and drug discovery. Researchers and industry professionals frequently search for "2-(7-Bromo-1H-indol-3-yl)ethan-1-ol uses" or "CAS 936252-65-2 suppliers," reflecting its growing relevance in scientific applications.

The molecular structure of 2-(7-Bromo-1H-indol-3-yl)ethan-1-ol features a 7-bromo substitution on the indole ring, which enhances its reactivity in cross-coupling reactions—a hot topic in modern synthetic chemistry. This property makes it valuable for constructing complex molecules, particularly in the development of targeted therapies and biologically active compounds. Recent trends in "indole derivatives in drug discovery" highlight the compound's potential in addressing unmet medical needs, such as neurological disorders and oncology research.

From a commercial perspective, CAS 936252-65-2 is available through specialized chemical suppliers, often with >95% purity for research purposes. The demand for "high-purity brominated indoles" has risen due to their role in high-throughput screening and medicinal chemistry. Analytical techniques like HPLC and NMR are typically employed to verify the compound's quality, addressing common queries such as "how to analyze 2-(7-Bromo-1H-indol-3-yl)ethan-1-ol."

In biochemical applications, this compound's hydrophilic-lipophilic balance (due to its hydroxyethyl group) enables diverse interactions with biological targets. This aligns with current searches for "indole-based enzyme inhibitors" and "small molecule modulators." Its stability under physiological conditions makes it suitable for in vitro studies, particularly in neurotransmitter research where indole derivatives play a crucial role.

The synthesis of 2-(7-Bromo-1H-indol-3-yl)ethan-1-ol typically involves electrophilic bromination of indole precursors, followed by side-chain modification—a process frequently explored in "green chemistry approaches to heterocycles" discussions. Environmental considerations have led to innovations in solvent-free or catalytic methods, responding to industry demands for "sustainable indole synthesis."

Market analysis indicates steady growth for bromoindole derivatives, driven by pharmaceutical R&D investments. The compound's patent landscape reveals applications in GPCR-targeting drugs and kinase inhibitors, addressing popular queries like "indole compounds in clinical trials." Regulatory-compliant sourcing is critical, as evidenced by searches for "REACH-certified 936252-65-2."

Storage recommendations for CAS 936252-65-2 emphasize protection from light and moisture at -20°C, with material safety data sheets (MSDS) providing detailed handling guidelines. These precautions align with laboratory best practices for "handling sensitive organic intermediates," a common concern among researchers.

Future prospects for 2-(7-Bromo-1H-indol-3-yl)ethan-1-ol include expanded use in proteomics and chemical biology tool development. Its structural features enable conjugation with fluorescent tags or biotin—addressing trending topics like "chemical probes for target identification." As the scientific community continues exploring "indole scaffolds for drug design," this compound remains a key player in innovative therapeutic strategies.

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