• 1. An approach to the structure and vibrational analysis of cis- and trans-3-chlorostyrene through IR/Raman and INS spectroscopies and theoretical ab initio/DFT calculations?
  J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
• 2. An integrated process of CO2 capture and in situ hydrogenation to formate using a tunable ethoxyl-functionalized amidine and Rh/bisphosphine system?
  Yu-Nong Li,Liang-Nian He,Xian-Dong Lang,Xiao-Fang Liu,Shuai Zhang RSC Adv., 2014,4, 49995-50002
• 3. An amide probe as a selective Al3+ and Fe3+ sensor inside the HeLa and a549 cell lines: Pictet–Spengler reaction for the rapid detection of tryptophan amino acid?
  Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877
• 4. An atomic scale study of defects in Co2FeAl
  Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
• 5. An antimonate pyrochlore (H1.23Sr0.45SbO3.48) for photocatalytic oxidation of benzene: effective oxygen usage and excellent activity?
  Jing Chen,Yu Shao,Danzhen Li J. Mater. Chem. A, 2017,5, 937-941

(R)-4-Propylpyrrolidin-2-one: A Comprehensive Overview

The compound CAS No. 930123-37-8, also known as (R)-4-Propylpyrrolidin-2-one, is a significant molecule in the field of organic chemistry and pharmacology. This compound belongs to the class of pyrrolidinones, which are cyclic ketones with a five-membered ring containing one oxygen atom. The propyl substituent at the 4-position of the pyrrolidinone ring introduces unique chemical and physical properties, making it a subject of interest in various research domains.

Recent studies have highlighted the potential of (R)-4-Propylpyrrolidin-2-one in drug discovery and development. Its stereochemistry, particularly the (R) configuration, plays a crucial role in its biological activity and selectivity. Researchers have explored its role as a building block in synthesizing complex molecules, including bioactive compounds with therapeutic potential.

The synthesis of (R)-4-Propylpyrrolidin-2-one involves a multi-step process that combines organic synthesis techniques with stereochemical control. Key steps include the formation of the pyrrolidinone ring through cyclization reactions and the introduction of the propyl group via alkylation or alkyne metathesis. These methods ensure high yields and excellent stereochemical outcomes, which are essential for maintaining the compound's biological activity.

In terms of applications, (R)-4-Propylpyrrolidin-2-one has shown promise in the development of chiral catalysts and ligands for asymmetric synthesis. Its ability to form stable complexes with transition metals makes it a valuable tool in enantioselective catalysis, which is critical for producing enantiopure pharmaceuticals.

Furthermore, recent advancements in computational chemistry have enabled researchers to model the electronic structure and reactivity of (R)-4-Propylpyrrolidin-2-one. These studies provide insights into its interaction with biological targets, such as enzymes and receptors, which is vital for understanding its pharmacological effects.

The compound's solubility and stability under various conditions have also been extensively studied. These properties are critical for its use in pharmaceutical formulations and industrial applications. For instance, its ability to dissolve in both polar and non-polar solvents makes it suitable for a wide range of chemical reactions and processes.

In conclusion, (R)-4-Propylpyrrolidin-2-one (CAS No. 930123-37-8) is a versatile compound with significant potential in organic synthesis, catalysis, and drug discovery. Its unique chemical properties and stereochemical features make it a valuable asset in advancing scientific research and industrial applications.

• 181289-22-5(2-Pyrrolidinone, 4-(2-methylpropyl)-, (4R)-)
• 89895-19-2(4-Propylpyrrolidin-2-one)
• 181289-23-6((S)-Pregabalin Lactam)
• 881315-76-0((4R)-4-(propan-2-yl)pyrrolidin-2-one)
• 89895-18-1(4-(propan-2-yl)pyrrolidin-2-one)
• 114601-41-1(4-(5-oxopyrrolidin-3-yl)pyrrolidin-2-one)
• 259857-48-2((4S)-4-(Propan-2-yl)pyrrolidin-2-one)
• 457893-17-3(4-butylpyrrolidin-2-one)
• 61312-87-6(4-Isobutyl-2-pyrrolidinone (pregabalin lactam impurity))
• 41819-75-4(4-ethylpyrrolidin-2-one)