Cas no 927652-04-8 (tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate)

Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate is a chiral pyrrolidine derivative commonly employed as a key intermediate in pharmaceutical synthesis. Its stereospecific (3S) configuration and carbamate-protected amine group make it valuable for constructing biologically active compounds, particularly in the development of enantiomerically pure drugs. The tert-butyloxycarbonyl (Boc) group provides stability under basic conditions while allowing selective deprotection under acidic conditions, facilitating controlled synthetic transformations. This compound’s rigid pyrrolidine scaffold enhances conformational control in target molecules. Its high purity and well-defined stereochemistry are critical for applications in medicinal chemistry, where precise structural features are required for optimal activity and selectivity.
tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate structure
927652-04-8 structure
Product Name:tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate
CAS No:927652-04-8
MF:C10H20N2O2
MW:200.278002738953
MDL:MFCD24368658
CID:1034851
PubChem ID:51041669
Update Time:2025-06-21

tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate Chemical and Physical Properties

Names and Identifiers

    • (S)-tert-Butyl (3-methylpyrrolidin-3-yl)carbamate
    • (S)-tert-butyl 3-methylpyrrolidin-3-ylcarbamate
    • TERT-BUTYL ((3S)-3-METHYLPYRROLIDIN-3-YL)CARBAMATE
    • tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate
    • (S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
    • SCHEMBL13739930
    • DTXSID10679605
    • CMB65204
    • MFCD24368658
    • tert-butyl (S)-(3-methylpyrrolidin-3-yl)carbamate
    • 927652-04-8
    • tert-Butyl [(3S)-3-methylpyrrolidin-3-yl]carbamate
    • W13804
    • EN300-3068259
    • DIQWSFWWYVRXRO-JTQLQIEISA-N
    • (S)-tert-Butyl(3-methylpyrrolidin-3-yl)carbamate
    • (3S)-3-(Boc-amino)-3-methylpyrrolidine
    • AS-78815
    • DB-310471
    • MDL: MFCD24368658
    • Inchi: 1S/C10H20N2O2/c1-9(2,3)14-8(13)12-10(4)5-6-11-7-10/h11H,5-7H2,1-4H3,(H,12,13)/t10-/m0/s1
    • InChI Key: DIQWSFWWYVRXRO-JTQLQIEISA-N
    • SMILES: O(C(C)(C)C)C(N[C@]1(C)CNCC1)=O

Computed Properties

  • Exact Mass: 200.152477885g/mol
  • Monoisotopic Mass: 200.152477885g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 4
  • Complexity: 223
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.9
  • Topological Polar Surface Area: 50.4?2

tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-1g
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
1g
11702.99CNY 2021-05-07
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-5g
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
5g
41384.47CNY 2021-05-07
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-500mg
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
500mg
6275.51CNY 2021-05-07
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-250mg
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
250mg
3561.78CNY 2021-05-07
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-100mg
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
100mg
2204.91CNY 2021-05-07
JIE DA WEI ( SHANG HAI ) YI YAO KE JI FA ZHAN Co., Ltd.
75R0511-50mg
(S)-(3-Methyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester
927652-04-8 97%
50mg
1526.48CNY 2021-05-07
abcr
AB544113-100 mg
(S)-tert-Butyl (3-methylpyrrolidin-3-yl)carbamate, 95%; .
927652-04-8 95%
100MG
€641.40 2023-07-11
abcr
AB544113-250 mg
(S)-tert-Butyl (3-methylpyrrolidin-3-yl)carbamate, 95%; .
927652-04-8 95%
250MG
€938.90 2023-07-11
eNovation Chemicals LLC
Y1056155-1g
tert-butyl N-[(3S)-3-Methylpyrrolidin-3-yl]carbaMate
927652-04-8 97%
1g
$1400 2024-06-05
eNovation Chemicals LLC
Y1056155-5g
tert-butyl N-[(3S)-3-Methylpyrrolidin-3-yl]carbaMate
927652-04-8 97%
5g
$3800 2024-06-05

Additional information on tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate

Introduction to Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate (CAS No. 927652-04-8)

Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate, a compound with the chemical formula C11H19N2O2, is a significant molecule in the field of pharmaceutical chemistry. This compound is characterized by its unique structural features, which include a tert-butyl group and a (3S)-3-methylpyrrolidin-3-yl moiety. The CAS number 927652-04-8 provides a unique identifier for this substance, facilitating its recognition and study in various scientific contexts.

The tert-butyl group is a branched alkyl group that enhances the lipophilicity of the molecule, making it more soluble in organic solvents. This property is particularly valuable in pharmaceutical formulations where solubility plays a crucial role in drug delivery and bioavailability. On the other hand, the (3S)-3-methylpyrrolidin-3-yl moiety contributes to the chirality of the compound, which is essential for many biological activities. Chiral drugs often exhibit different pharmacological properties depending on their stereochemistry, making the precise control of stereochemistry during synthesis critical.

In recent years, there has been growing interest in the development of novel carbamate-based compounds due to their diverse biological activities. Carbamates are known for their ability to act as intermediates in the synthesis of various pharmacologically active agents. The compound Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate has garnered attention for its potential applications in the treatment of neurological disorders. Studies have shown that carbamate derivatives can interact with specific enzymes and receptors, modulating neural activity and potentially offering therapeutic benefits.

One of the most compelling aspects of Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate is its structural similarity to known bioactive molecules. This similarity suggests that it may possess similar pharmacological properties, although further research is needed to fully elucidate its mechanism of action. Researchers have been exploring its potential as a precursor for more complex drug molecules, leveraging its unique structural features to design new compounds with enhanced efficacy and reduced side effects.

The synthesis of Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate involves multi-step organic reactions, requiring precise control over reaction conditions to ensure high yield and purity. The use of chiral auxiliaries or catalysts is often necessary to achieve the desired stereochemical outcome. Advances in synthetic methodologies have made it possible to produce this compound with increasing efficiency, paving the way for larger-scale applications in drug development.

Recent studies have also highlighted the importance of understanding the metabolic pathways involving Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate. Metabolism plays a critical role in determining the bioavailability and toxicity of a drug, and identifying key metabolic pathways can help optimize drug design. Researchers are using computational modeling and experimental techniques to predict how this compound might be metabolized in vivo, providing valuable insights into its potential therapeutic applications.

The pharmaceutical industry continues to invest heavily in research aimed at discovering new therapeutic agents. Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate represents an exciting example of how structural modifications can lead to novel bioactive compounds. By understanding its properties and potential applications, scientists can develop new drugs that address unmet medical needs more effectively.

In conclusion, Tert-butyl N-[(3S)-3-methylpyrrolidin-3-yl]carbamate (CAS No. 927652-04-8) is a promising compound with significant potential in pharmaceutical research. Its unique structural features, combined with its biological activity, make it an attractive candidate for further investigation. As our understanding of its properties and mechanisms continues to grow, so too will its potential applications in medicine.

Recommended suppliers
Beyond Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shanghai Pearlk Chemicals Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jiangxi Boyang Pharmaceutical Chemical Co., Ltd
Shandong Feiyang Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Shandong Feiyang Chemical Co., Ltd
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
SHOCHEM(SHANGHAI) CO.,lTD