• 1. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 2. Emerging investigator series: kinetics of diopside reactivity for carbon mineralization in mafic–ultramafic rocks
  BrianaAguila,LandonHardee,H.ToddSchaef,SiavashZare,MohammadJavadAbdolhosseiniQomi,JarrodV.Crum,JadeE.HollimanJr.,ElenaTajueloRodriguez,LawrenceM.Anovitz,KevinM.Rosso,QuinR.S.Miller
• 3. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imaging
  Ghazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
• 4. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 5. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555

• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthalenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes

Comprehensive Overview of 2-(6-bromo-2-methoxynaphthalen-1-yl)acetonitrile (CAS No. 92643-17-9)

2-(6-bromo-2-methoxynaphthalen-1-yl)acetonitrile (CAS No. 92643-17-9) is a specialized organic compound that has garnered significant attention in pharmaceutical and material science research. This compound, characterized by its naphthalene backbone substituted with a bromo and methoxy group, serves as a critical intermediate in the synthesis of various bioactive molecules. Its unique structure makes it a valuable building block for developing drug candidates, fluorescent probes, and advanced materials.

The growing interest in 2-(6-bromo-2-methoxynaphthalen-1-yl)acetonitrile is driven by its versatility in organic synthesis. Researchers are particularly intrigued by its potential applications in cancer therapeutics and neurodegenerative disease research, areas that dominate current scientific discourse. With the rise of AI-driven drug discovery, this compound has been flagged in computational studies for its favorable pharmacokinetic properties, further boosting its relevance in modern chemistry.

One of the most searched questions about CAS No. 92643-17-9 revolves around its synthetic routes. The compound is typically prepared via Pd-catalyzed cross-coupling reactions, a method widely discussed in academic forums and patent literature. Its bromo-substituted naphthalene core allows for further functionalization, making it a hotspot for structure-activity relationship (SAR) studies. This adaptability aligns with the industry’s shift toward green chemistry, as researchers explore solvent-free or catalytic methods to optimize its production.

In material science, 2-(6-bromo-2-methoxynaphthalen-1-yl)acetonitrile is investigated for its role in designing organic semiconductors and OLED materials. The compound’s electron-withdrawing nitrile group and extended conjugation system contribute to charge transport properties, a topic trending in renewable energy circles. As the demand for flexible electronics grows, this compound’s derivatives are being tested for their thermal stability and luminescent efficiency.

From an analytical perspective, 92643-17-9 is often analyzed using HPLC, NMR, and mass spectrometry to ensure purity—a key concern for laboratories focused on high-throughput screening. Recent publications highlight its compatibility with microwave-assisted synthesis, a technique gaining traction for reducing reaction times. These advancements cater to the pharmaceutical industry’s push for cost-effective scalability, another frequently searched topic in chemical databases.

Environmental and regulatory considerations for 2-(6-bromo-2-methoxynaphthalen-1-yl)acetonitrile are also under scrutiny. While not classified as hazardous, its handling requires standard precautions, aligning with global laboratory safety protocols. The compound’s biodegradability and ecotoxicology profile are subjects of ongoing studies, reflecting the broader emphasis on sustainable chemistry in peer-reviewed journals.

In summary, CAS No. 92643-17-9 exemplifies the intersection of synthetic utility and multidisciplinary innovation. Its applications span medicinal chemistry, materials engineering, and analytical technology, addressing pressing challenges in healthcare and energy. As research evolves, this compound is poised to remain a focal point for scientists exploring next-generation functional materials and targeted therapies.

• 71056-97-8(2-(2-methoxynaphthalen-1-yl)acetonitrile)
• 858523-37-2(2-(4-bromo-2-methoxyphenyl)acetonitrile)
• 33839-11-1(4-Bromo-2-ethyl-1-methoxybenzene)
• 876299-65-9(4-Bromo-1-ethyl-2-methoxybenzene)
• 163259-83-4(3-(5-Bromo-2-methoxyphenyl)propanenitrile)
• 162271-09-2(Benzeneacetonitrile, 5-bromo-2-(methoxymethoxy)-)
• 53863-58-4(14H-DIBENZO[A,J]XANTHENE, 3,11-DIBROMO-)
• 69405-10-3(2-NAPHTHALENEACETONITRILE, 5-BROMO-6-METHOXY-)
• 143210-25-7(2-Naphthalenol, 1,1'-[(2-methoxyphenyl)methylene]bis[6-bromo-)
• 7062-40-0(2-(5-Bromo-2-methoxyphenyl)acetonitrile)