• 1. Emergence of cationic polyamine dendrimersomes: design, stimuli sensitivity and potential biomedical applications
  Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
• 2. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
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• 3. Distinct correlation between (CN2)x units and pores: a low-cost method for predesigned wide range control of micropore size of porous carbon?
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• Solvents and Organic Chemicals Organic Compounds Organic nitrogen compounds Organonitrogen compounds Cyclohexylamines

Comprehensive Overview of (3-aminocyclohexyl)methanol (CAS No. 925921-14-8): Properties, Applications, and Industry Insights

(3-aminocyclohexyl)methanol, identified by its CAS number 925921-14-8, is a versatile organic compound with significant relevance in pharmaceutical and chemical research. This cyclohexane derivative features both an amino group and a hydroxyl group, making it a valuable intermediate for synthesizing complex molecules. Its unique structure enables applications in drug discovery, agrochemicals, and specialty materials, aligning with growing industry demands for high-purity intermediates and custom synthesis solutions.

The compound’s molecular formula, C₇H₁₅NO, reflects its balanced hydrophilicity and lipophilicity, a trait highly sought after in bioactive molecule design. Researchers frequently explore (3-aminocyclohexyl)methanol for its potential in modulating pharmacokinetic properties, particularly in CNS-targeting therapeutics—a trending focus area due to rising neurological disorder cases globally. Recent studies highlight its utility in creating chiral building blocks, addressing the pharmaceutical industry’s need for enantioselective synthesis.

From a technical perspective, 925921-14-8 exhibits stability under standard storage conditions (room temperature, inert atmosphere), though its amino-alcohol functionality necessitates moisture-sensitive handling. Analytical techniques like HPLC and GC-MS are commonly employed for purity verification, with ≥98% purity being the commercial benchmark. Suppliers often emphasize cGMP compliance and scalable production capabilities to meet regulatory requirements—a critical consideration for buyers in regulated markets.

Market trends indicate heightened interest in sustainable synthetic routes for compounds like (3-aminocyclohexyl)methanol, driven by green chemistry initiatives. Catalytic hydrogenation and enzymatic resolution methods are gaining traction over traditional stoichiometric processes, reducing environmental impact while maintaining yield efficiency. This aligns with frequent search queries such as "eco-friendly amine synthesis" and "cost-effective chiral alcohol production", reflecting industry priorities.

In pharmaceutical applications, this compound serves as a precursor for protease inhibitors and kinase modulators, with patent literature citing its role in oncology and antiviral drug candidates. Its structural flexibility allows derivatization at both functional groups, enabling medicinal chemists to fine-tune target selectivity—an advantage frequently discussed in drug discovery forums and medicinal chemistry publications.

Quality control protocols for CAS 925921-14-8 typically include rigorous testing for residual solvents, heavy metals, and isomeric purity, addressing concerns about batch-to-batch consistency. Leading manufacturers now provide comprehensive analytical certificates and structure-activity relationship data, responding to buyer demands for transparency in the fine chemicals supply chain.

Emerging applications in material science include its use as a monomer for polyurethane modifications and epoxy resin curing agents, where its cycloaliphatic structure enhances thermal stability. These developments correlate with increasing searches for "high-performance polymer additives", demonstrating cross-industry relevance beyond life sciences.

Regulatory landscapes continue to evolve, with REACH compliance and FDA DMF filings becoming decisive factors for procurement teams. Proactive suppliers are investing in regulatory support services alongside product offerings, recognizing that seamless documentation accelerates research timelines—a key pain point voiced in procurement surveys and industry white papers.

Future research directions may explore (3-aminocyclohexyl)methanol's potential in bioconjugation chemistry and targeted drug delivery systems, particularly for blood-brain barrier penetration. Such applications could address frequently searched challenges like "CNS drug bioavailability improvement", positioning this compound as an enabler for next-generation therapeutics.

• 216700-32-2(Cyclohexanol,4-amino-2-methyl-, (1R,2R)-rel-)
• 5691-21-4(trans-2-aminocyclohexyl]methanol)
• 857831-26-6(2-(4-Aminocyclohexyl)ethanol)
• 61367-22-4(cis-4-aminocyclohexanemethanol hydrochloride)
• 213993-30-7([(1S,2R)-2-aminocyclohexyl]methanol)
• 213993-31-8(Cyclohexanemethanol,2-amino-, (1S,2S)-)
• 30134-98-6(cis-4-aminocyclohexyl methanol)
• 89854-95-5((4-Aminocyclohexyl)methanol hydrochloride (1:1))
• 1504-49-0(trans-4-Aminocyclohexanemethanol hydrochloride)
• 1467-84-1([trans-4-aminocyclohexyl]methanol)