Cas no 92381-62-9 (3H-Imidazo[4,5-c]pyridine-2-methanol)

3H-Imidazo[4,5-c]pyridine-2-methanol is a heterocyclic compound featuring an imidazopyridine core with a hydroxymethyl functional group at the 2-position. This structure imparts versatility in synthetic applications, particularly in pharmaceutical and agrochemical research, where it serves as a key intermediate for the development of bioactive molecules. The hydroxymethyl group enhances reactivity, enabling further functionalization through esterification, etherification, or oxidation. Its rigid fused-ring system contributes to stability while maintaining compatibility with diverse reaction conditions. The compound is of interest in medicinal chemistry due to its potential as a scaffold for kinase inhibitors or other targeted therapeutics. Proper handling under inert conditions is recommended to preserve its integrity.
3H-Imidazo[4,5-c]pyridine-2-methanol structure
92381-62-9 structure
Product Name:3H-Imidazo[4,5-c]pyridine-2-methanol
CAS No:92381-62-9
MF:C7H7N3O
MW:149.149980783463
CID:839300
PubChem ID:23298388
Update Time:2025-06-09

3H-Imidazo[4,5-c]pyridine-2-methanol Chemical and Physical Properties

Names and Identifiers

    • 3H-Imidazo[4,5-c]pyridine-2-methanol
    • (3H-imidazo[4,5-c]pyridin-2-yl)methanol
    • 1H-Imidazo[4,5-c]pyridine-2-methanol
    • 3H-imidazo[4,5-c]pyridin-2-ylmethanol
    • Imidazo[4,5-c]pyridine-2-methanol
    • AKOS012572170
    • SCHEMBL5806722
    • 2-hydroxymethyl-1H-imidazo[4,5-c]pyridine
    • 92381-62-9
    • ILSGRMBFKUPLSU-UHFFFAOYSA-N
    • DTXSID90632697
    • DB-327745
    • Inchi: 1S/C7H7N3O/c11-4-7-9-5-1-2-8-3-6(5)10-7/h1-3,11H,4H2,(H,9,10)
    • InChI Key: ILSGRMBFKUPLSU-UHFFFAOYSA-N
    • SMILES: OCC1=NC2C=CN=CC=2N1

Computed Properties

  • Exact Mass: 149.058911855g/mol
  • Monoisotopic Mass: 149.058911855g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 142
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.4
  • Topological Polar Surface Area: 61.8?2

Experimental Properties

  • Melting Point: 198 oC

3H-Imidazo[4,5-c]pyridine-2-methanol Pricemore >>

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Additional information on 3H-Imidazo[4,5-c]pyridine-2-methanol

Comprehensive Overview of 3H-Imidazo[4,5-c]pyridine-2-methanol (CAS No. 92381-62-9): Properties, Applications, and Research Insights

3H-Imidazo[4,5-c]pyridine-2-methanol (CAS No. 92381-62-9) is a heterocyclic organic compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural framework. The compound belongs to the imidazopyridine family, a class of molecules known for their diverse biological activities. Its molecular formula, C7H7N3O, and the presence of both imidazole and pyridine rings make it a versatile scaffold for drug discovery and material science applications.

Researchers have explored 3H-Imidazo[4,5-c]pyridine-2-methanol for its potential as a building block in the synthesis of bioactive molecules. Its methanol functional group allows for further chemical modifications, enabling the creation of derivatives with enhanced properties. Recent studies highlight its relevance in targeting enzyme inhibitors and receptor modulators, particularly in the context of neurodegenerative diseases and metabolic disorders. This aligns with the growing public interest in precision medicine and personalized therapeutics, topics frequently searched in academic and healthcare forums.

The compound’s physicochemical properties, such as solubility, stability, and reactivity, have been extensively documented. For instance, its logP value suggests moderate lipophilicity, which is crucial for optimizing drug delivery systems. These characteristics are often discussed in QSAR (Quantitative Structure-Activity Relationship) studies, a trending topic in computational chemistry and AI-driven drug design. As the demand for green chemistry and sustainable synthesis methods rises, 92381-62-9 has also been evaluated for eco-friendly production pathways.

In the realm of material science, 3H-Imidazo[4,5-c]pyridine-2-methanol has shown promise in the development of organic semiconductors and fluorescent probes. Its conjugated system and electron-rich nitrogen atoms contribute to its optical and electronic properties, making it a candidate for OLEDs (Organic Light-Emitting Diodes) and sensors. This application resonates with the surge in searches for renewable energy materials and smart technologies.

Safety and regulatory aspects of CAS No. 92381-62-9 are equally critical. While the compound is not classified as hazardous under current guidelines, proper handling protocols are recommended to ensure workplace safety. This aligns with the increasing public awareness of chemical safety data sheets (SDS) and laboratory best practices, frequently queried by professionals and students alike.

In summary, 3H-Imidazo[4,5-c]pyridine-2-methanol represents a multifaceted compound with applications spanning pharmaceuticals, materials science, and biotechnology. Its structural versatility and adaptability to modern research trends underscore its importance in both academic and industrial settings. As scientific inquiries continue to evolve, this compound is poised to remain a focal point in innovative research and development.

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