• 1. Dissociative dynamics of O2 on Ag(110)?
  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
• 2. Excellent energy storage performance in NaNbO3-based relaxor antiferroeic ceramics under a low electric field
  XuxinCheng,XiaomingChen,PengyuanFan
• 3. Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers?
  Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
• 4. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenols Methoxyphenols

4-Hydroxy-3-Methoxybenzene-1-Sulfonyl Chloride: A Comprehensive Overview

The compound with CAS No. 914261-11-3, commonly referred to as 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride, is a significant molecule in the field of organic chemistry. This compound is characterized by its unique structure, which includes a sulfonyl chloride group attached to a benzene ring substituted with hydroxyl and methoxy groups. The presence of these functional groups imparts distinctive chemical properties, making it a valuable compound in various applications.

Recent studies have highlighted the importance of sulfonyl chloride derivatives in the synthesis of bioactive compounds. The 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride has been explored for its potential in drug discovery, particularly in the development of anti-inflammatory and antioxidant agents. Researchers have found that the hydroxyl and methoxy groups on the benzene ring contribute to the molecule's ability to interact with biological systems, enhancing its pharmacological properties.

The synthesis of 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride involves a multi-step process that begins with the preparation of the corresponding sulfonic acid derivative. This is followed by conversion into the sulfonyl chloride using thionyl chloride (SOCl?) under controlled conditions. The reaction conditions are critical to ensure high yield and purity of the final product. Recent advancements in catalytic methods have improved the efficiency of this synthesis, making it more accessible for large-scale production.

In terms of chemical reactivity, sulfonyl chlorides are known for their electrophilic nature, which makes them excellent substrates for nucleophilic substitutions. The 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride has been used as a building block in the construction of complex molecules, including pharmaceutical intermediates. Its reactivity is further modulated by the electron-donating hydroxyl and methoxy groups, which influence the electronic environment of the sulfonyl group.

Recent research has also focused on the environmental impact of synthesizing and using sulfonyl chlorides. Scientists have developed greener synthesis routes that minimize the use of hazardous reagents and reduce waste generation. For instance, the use of microwave-assisted synthesis has been reported to enhance reaction efficiency while reducing energy consumption. These advancements align with global efforts to promote sustainable chemistry practices.

The application of 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride extends beyond pharmaceuticals. It has been explored in materials science for its potential as a precursor in polymer synthesis. The molecule's ability to form stable bonds with various monomers makes it a promising candidate for developing advanced materials with tailored properties.

In conclusion, 4-hydroxy-3-methoxybenzene-1-sulfonyl chloride is a versatile compound with significant potential in multiple fields. Its unique structure and reactivity make it an invaluable tool in organic synthesis, while ongoing research continues to uncover new applications and improve its production processes. As science progresses, this compound is expected to play an increasingly important role in both academic and industrial settings.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)