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• 3. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
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• 4. Fe(ii)-Assisted one-pot synthesis of ultra-small core–shell Au–Pt nanoparticles as superior catalysts towards the HER and ORR?
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones

Comprehensive Overview of 1-(2-Amino-4-(trifluoromethoxy)phenyl)ethanone (CAS No. 913569-24-1)

1-(2-Amino-4-(trifluoromethoxy)phenyl)ethanone, with the CAS number 913569-24-1, is a specialized organic compound that has garnered significant attention in pharmaceutical and agrochemical research. This compound features a unique molecular structure, combining an amino group and a trifluoromethoxy moiety, which enhances its reactivity and potential applications. Researchers are particularly interested in its role as a key intermediate in the synthesis of bioactive molecules, owing to its versatile chemical properties.

The growing demand for trifluoromethoxy-containing compounds in drug discovery has placed 1-(2-Amino-4-(trifluoromethoxy)phenyl)ethanone at the forefront of modern medicinal chemistry. Its electron-withdrawing trifluoromethoxy group improves metabolic stability and bioavailability, making it a valuable building block for targeted therapies. Recent studies highlight its potential in developing CNS-active drugs and antimicrobial agents, aligning with the current focus on combating antibiotic resistance and neurological disorders.

In the agrochemical sector, CAS 913569-24-1 is explored for its utility in designing novel pesticides and herbicides. The trifluoromethoxy group contributes to enhanced pesticidal activity, addressing the need for eco-friendly crop protection solutions. This aligns with the global push toward sustainable agriculture, a topic frequently searched by stakeholders in the agrochemical industry.

From a synthetic perspective, 1-(2-Amino-4-(trifluoromethoxy)phenyl)ethanone is synthesized via multi-step organic reactions, often involving Friedel-Crafts acylation and nitration-reduction sequences. Its purity and yield are critical for downstream applications, driving innovations in green chemistry and catalytic processes. Researchers are also investigating its structure-activity relationships (SAR) to optimize its performance in various applications.

The compound’s physicochemical properties, such as solubility and thermal stability, are well-documented, making it a reliable choice for high-throughput screening and combinatorial chemistry. Its molecular weight and logP value further support its suitability for drug-like molecules, a hot topic in computational chemistry and AI-driven drug design.

In summary, 1-(2-Amino-4-(trifluoromethoxy)phenyl)ethanone (CAS 913569-24-1) is a multifaceted compound with broad applications in pharmaceuticals, agrochemicals, and material science. Its unique structural features and functional groups make it a subject of ongoing research, particularly in areas like precision medicine and sustainable chemistry. As the scientific community continues to explore its potential, this compound is poised to play a pivotal role in addressing some of the most pressing challenges in modern science.

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