Cas no 911819-08-4 (Ophiopojaponin C)
Ophiopojaponin C Chemical and Physical Properties
Names and Identifiers
-
- Ophiopogonin C
- (3β,25R)-14,17-Dihydroxyspirost-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->4)]-β-D-glucopyranoside
- Ophiopojaponin C
- [14-[5-Hydroxy-6-methyl-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-4-(3,4,5-trihydroxyoxan-2-yl)oxyox
- (3β,25R)-14,17-Dihydroxyspirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranoside (ACI)
- Ophiopogenin 3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-xylopyranosyl-(1→4)-β-D-glucopyranoside
- 911819-08-4
- [(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-14-[(2S,3R,4S,5S,6R)-5-hydroxy-6-methyl-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl] acetate
- [(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-14-[(2S,3R,4S,5S,6R)-5-hydroxy-6-methyl-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02
- Ophiopojaponin-C
- Q-100888
- DA-66355
-
- Inchi: 1S/C44H70O18/c1-19-8-13-43(56-17-19)21(3)44(54)28(62-43)15-42(53)25-7-6-22-14-23(9-11-40(22,4)24(25)10-12-41(42,44)5)58-39-36(61-38-33(51)31(49)29(47)20(2)57-38)34(52)35(27(16-45)59-39)60-37-32(50)30(48)26(46)18-55-37/h6,19-21,23-39,45-54H,7-18H2,1-5H3/t19-,20+,21-,23+,24+,25-,26-,27-,28+,29+,30+,31-,32-,33-,34+,35-,36-,37+,38+,39-,40+,41+,42-,43-,44-/m1/s1
- InChI Key: KLOUOGJUAFMUDK-DGDLHAQSSA-N
- SMILES: O[C@]12[C@H](C)[C@]3(OC[C@H](C)CC3)O[C@H]1C[C@]1([C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]21C)O[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2OC[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)O
Computed Properties
- Exact Mass: 896.47695082 g/mol
- Monoisotopic Mass: 896.47695082 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 7
- Hydrogen Bond Acceptor Count: 17
- Heavy Atom Count: 63
- Rotatable Bond Count: 8
- Complexity: 1700
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 26
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 897.1
- XLogP3: 1.6
- Topological Polar Surface Area: 242
Experimental Properties
- Color/Form: Powder
- Density: 1.47
- Melting Point: No data available
- Boiling Point: No data available
- Flash Point: No data available
- Vapor Pressure: No data available
Ophiopojaponin C Security Information
- Signal Word:warning
- Hazard Statement: H303+H313+H333
- Warning Statement: P264+P280+P305+P351+P338+P337+P313
- Safety Instruction: H303+H313+H333
- Storage Condition:Store at 4 ° C, -4 ° C is better
Ophiopojaponin C Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd | BP3296-1000mg |
Ophiopojaponin C |
911819-08-4 | 98% | 1000mg |
$0 | 2023-09-20 | |
| Chengdu Biopurify Phytochemicals Ltd | BP3296-20mg |
Ophiopojaponin C |
911819-08-4 | 98% | 20mg |
$0 | 2023-09-20 | |
| Chengdu Biopurify Phytochemicals Ltd | BP3296-100mg |
Ophiopojaponin C |
911819-08-4 | 98% | 100mg |
$0 | 2023-09-20 | |
| SHANG HAI TAO SHU Biotechnology Co., Ltd. | T4104-1 mg |
Ophiopogonin C |
911819-08-4 | 1mg |
¥2035.00 | 2022-04-26 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | O46170-5mg |
Ophiopojaponin C |
911819-08-4 | 5mg |
¥2498.0 | 2021-09-08 | ||
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP0342-5mg |
Ophiopojaponin C |
911819-08-4 | HPLC≥98% | 5mg |
¥3800元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP1126-10mg |
Ophiopojaponin C |
911819-08-4 | HPLC≥98% | 10mg |
¥2820元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP0342-20mg |
Ophiopojaponin C |
911819-08-4 | HPLC≥98% | 20mg |
詢價 | 2021-06-16 | |
| DC Chemicals | DCM-063-20 mg |
Ophiopogonin C |
911819-08-4 | >98%, Standard References Grade | 20mg |
$280.0 | 2022-02-28 | |
| Chengdu Biopurify Phytochemicals Ltd | BP3296-1000mg |
Ophiopojaponin C |
911819-08-4 | 98% | 1000mg |
$0 | 2023-09-19 |
Ophiopojaponin C Related Literature
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Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
Additional information on Ophiopojaponin C
Introduction to Ophiopojaponin C (CAS No. 911819-08-4)
Ophiopojaponin C, a naturally occurring compound with the chemical designation CAS No. 911819-08-4, has garnered significant attention in the field of pharmaceutical research due to its unique structural properties and promising biological activities. This compound, isolated from the roots of Ophiopogon japonicus, a plant traditionally used in Eastern medicine, belongs to the saponin class of glycosides. The intricate molecular architecture of Ophiopojaponin C, characterized by its triterpene aglycone and sugar moieties, contributes to its diverse pharmacological potential.
Recent studies have highlighted the antimicrobial and anti-inflammatory properties of Ophiopojaponin C, making it a subject of intense investigation for potential therapeutic applications. Research indicates that this compound exerts its effects by modulating various cellular pathways, including those involved in immune response and oxidative stress regulation. The structural features of Ophiopojaponin C, particularly its hydroxylated and glycosidically linked regions, are believed to play a crucial role in its biological interactions.
In vitro and in vivo experiments have demonstrated that Ophiopojaponin C exhibits notable cytotoxicity against certain cancer cell lines, suggesting its potential as an anticancer agent. The mechanism of action appears to involve the induction of apoptosis and inhibition of cell proliferation, mechanisms that are currently under further exploration. Additionally, preliminary studies suggest that Ophiopojaponin C may possess neuroprotective properties, which could be relevant for the development of treatments for neurodegenerative diseases such as Alzheimer's and Parkinson's.
The synthesis and structural elucidation of Ophiopojaponin C have been areas of active interest in synthetic chemistry. Researchers have developed sophisticated methodologies to produce this compound in a laboratory setting, enabling more extensive pharmacological testing. Advances in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy have been instrumental in confirming the structural integrity of synthetic Ophiopojaponin C, ensuring that it mirrors the natural compound's configuration.
One of the most compelling aspects of Ophiopojaponin C is its potential for drug development due to its multifaceted biological activities. The compound's ability to interact with multiple targets within cellular systems makes it a promising candidate for combinatorial therapies. For instance, its anti-inflammatory effects could be synergistic when combined with traditional treatments for chronic inflammatory conditions. Furthermore, its antimicrobial properties may offer new strategies for combating drug-resistant bacterial infections.
The traditional use of Ophiopogon japonicus in herbal medicine has provided a rich foundation for modern pharmacological research. Ethnobotanical studies have long recognized the plant's therapeutic value, particularly for conditions related to inflammation and immune modulation. The isolation and characterization of compounds like Ophiopojaponin C bridge the gap between traditional knowledge and contemporary scientific inquiry, offering a novel perspective on natural product-based drug discovery.
As research on Ophiopojaponin C progresses, there is growing interest in understanding its pharmacokinetic profile and potential side effects. Preclinical studies are essential for determining dosing regimens and identifying any adverse reactions that might arise from prolonged exposure. These studies will also help elucidate how Ophiopojaponin C is metabolized within the body, providing insights into its bioavailability and duration of action.
The development of derivatives based on the structure of Ophiopojaponin C represents another exciting avenue for research. By modifying specific functional groups or introducing new chemical entities, scientists aim to enhance the compound's efficacy while minimizing potential toxicity. Such modifications could lead to novel therapeutic agents with improved pharmacological profiles suitable for clinical use.
The global interest in natural products as sources of bioactive compounds underscores the importance of continued research into species like Ophiopogon japonicus. The discovery of compounds such as Ophiopojaponin C not only expands our understanding of plant-derived pharmaceuticals but also offers hope for addressing unmet medical needs through innovative drug development strategies.
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