• 1. Distinct impact of glycation towards the aggregation and toxicity of murine and human amyloid-β?
  Eunju Nam,Jiyeon Han,Sunhee Choi,Mi Hee Lim Chem. Commun., 2021,57, 7637-7640
• 2. Estimates of hydride ion stability in condensed systems: energy of formation and solvation in aqueous and polar-organic solvents
  Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
• 3. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 4. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
• 5. Fe/S-Catalyzed synthesis of 2-benzoylbenzoxazoles and 2-quinolylbenzoxazoles via redox condensation of o-nitrophenols with acetophenones and methylquinolines?
  Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Phenylmethylamines

(3-Fluorophenyl)methyl(pentyl)amine: A Comprehensive Overview

(3-Fluorophenyl)methyl(pentyl)amine, identified by the CAS number 90389-88-1, is a compound of significant interest in various fields of chemistry and materials science. This compound, with its unique structure and properties, has garnered attention due to its potential applications in drug design, polymer synthesis, and advanced materials. The name itself highlights its structural components: a pentyl group attached to an amine functional group, with a fluorinated phenyl ring providing additional chemical complexity.

The chemical structure of (3-fluorophenyl)methyl(pentyl)amine consists of a pentyl chain (C5H11) linked to an amine group (-NH-) and a fluorinated phenyl ring. The fluorine atom at the 3-position of the phenyl ring introduces electronic effects that can influence the compound's reactivity and stability. This structural feature makes it a valuable building block in organic synthesis, particularly in the creation of bioactive molecules and functional polymers.

Recent studies have explored the role of fluorinated amines like this compound in drug discovery. Fluorine substitution is known to enhance the pharmacokinetic properties of molecules, such as increasing lipophilicity and improving metabolic stability. These attributes make (3-fluorophenyl)methyl(pentyl)amine a promising candidate for use in medicinal chemistry, where fine-tuning molecular properties is crucial for developing effective therapeutic agents.

In terms of synthesis, this compound can be prepared through various methods, including nucleophilic substitution reactions or coupling reactions involving appropriate precursors. The choice of synthetic pathway depends on the availability of starting materials and the desired purity of the final product. Researchers have also investigated green chemistry approaches to synthesize this compound, aiming to minimize environmental impact while maintaining high yields.

The physical properties of (3-fluorophenyl)methyl(pentyl)amine are influenced by its molecular weight and functional groups. It exhibits moderate solubility in common organic solvents and has a melting point that is typical for compounds with similar structures. Its thermal stability has been studied under various conditions, making it suitable for use in high-temperature applications or reactions requiring robustness against thermal degradation.

Applications of this compound extend beyond pharmaceuticals. In materials science, it has been utilized as a precursor for synthesizing advanced polymers with tailored mechanical and electronic properties. For instance, incorporating this amine into polymer backbones can enhance their conductivity or mechanical strength, making them suitable for use in electronics or composite materials.

Moreover, recent advancements in computational chemistry have enabled detailed modeling of (3-fluorophenyl)methyl(pentyl)amine's interactions within biological systems. Molecular docking studies have revealed potential binding affinities with key proteins, suggesting its role as a lead compound in drug development efforts targeting specific diseases such as cancer or neurodegenerative disorders.

In conclusion, (3-fluorophenyl)methyl(pentyl)amine, CAS No. 90389-88-1, stands out as a versatile compound with diverse applications across multiple disciplines. Its unique structure, combined with favorable chemical properties and recent research findings, positions it as an important tool in modern chemistry and materials science.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)