• 1. Embedding heteroatoms: an effective approach to create porphyrin-based functional materials
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  Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
• 3. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
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• 4. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Aminopyridines and derivatives

Comprehensive Overview of 4-Pyridinamine,3,5-diethyl- (CAS No. 900804-08-2): Properties, Applications, and Industry Insights

4-Pyridinamine,3,5-diethyl- (CAS No. 900804-08-2) is a specialized organic compound belonging to the pyridine derivative family. Its molecular structure features ethyl substituents at the 3 and 5 positions of the pyridine ring, which significantly influence its chemical reactivity and physical properties. This compound has garnered attention in pharmaceutical research, agrochemical development, and material science due to its unique structural characteristics. Researchers often refer to it by alternative names such as 3,5-diethyl-4-pyridinamine or 4-amino-3,5-diethylpyridine, highlighting its functional groups and substitution pattern.

The growing interest in pyridine derivatives like 4-Pyridinamine,3,5-diethyl- stems from their versatile applications in drug discovery. Recent studies explore its potential as a building block for kinase inhibitors and neurotransmitter analogs, addressing trending topics in precision medicine and neurological disorder treatments. The compound's balanced lipophilicity, achieved through the ethyl groups, makes it particularly valuable for optimizing drug bioavailability—a key concern in modern pharmacokinetic research.

From a synthetic chemistry perspective, CAS 900804-08-2 demonstrates interesting reactivity patterns. The electron-donating effect of the ethyl groups activates the pyridine ring toward electrophilic substitution, while the amino group at position 4 serves as an excellent directing group for further functionalization. These properties align with current industry demands for modular synthetic platforms, as evidenced by its use in creating diverse molecular libraries for high-throughput screening.

Material scientists have investigated 3,5-diethyl-4-pyridinamine for its potential in organic electronics. Its conjugated system and ability to form stable coordination complexes make it a candidate for organic semiconductors and metal-organic frameworks (MOFs)—areas experiencing exponential growth due to renewable energy initiatives. The compound's thermal stability (typically >200°C) further enhances its suitability for these applications.

Analytical characterization of 4-Pyridinamine,3,5-diethyl- typically involves advanced techniques such as HPLC-MS and NMR spectroscopy. The mass spectrum generally shows a molecular ion peak at m/z 150.22 [M+H]+, while ¹H NMR displays characteristic signals between δ 1.2-1.4 ppm (ethyl CH₃) and δ 2.5-2.7 ppm (ethyl CH₂). These analytical fingerprints are crucial for quality control in commercial production.

Environmental and safety assessments indicate that 900804-08-2 requires standard laboratory handling precautions. While not classified as highly hazardous, proper PPE including gloves and goggles is recommended during manipulation. The compound's environmental persistence and biodegradation profile remain active research areas, particularly regarding green chemistry applications.

The commercial availability of 4-Pyridinamine,3,5-diethyl- has expanded significantly since 2020, with global suppliers offering various purity grades (98-99.5%). Pricing trends reflect increasing demand from contract research organizations and academic institutions. Current market analyses suggest compound annual growth rate (CAGR) of 6-8% for similar pyridine derivatives through 2028.

Future research directions for CAS 900804-08-2 include exploration of its supramolecular chemistry properties and potential in catalytic systems. The compound's ability to participate in hydrogen bonding networks makes it particularly interesting for designing molecular recognition systems. These developments align with broader industry shifts toward sustainable chemical processes and functional materials.

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