• 1. An intermolecular C–C coupling reaction of iridium complexes?
  Kathrin Kutlescha,Rhett Kempe New J. Chem., 2010,34, 1954-1960
• 2. An interplay between electronic and structural effects on the photoluminescence decay mechanisms in LaPO4·nH2O:Tb3+ and LaPO4:Tb3+ single-crystal nanorods?
  M. T. Colomer,S. Díaz-Moreno,A. Tamayo,A. L. Ortiz J. Mater. Chem. C, 2018,6, 12643-12651
• 3. An AuNPs-functionalized AlGaN/GaN high electron mobility transistor sensor for ultrasensitive detection of TNT?
  Ying Li,Weirong Yao,Yunfei Xie,Renjun Pei RSC Adv., 2015,5, 98724-98729
• 4. An ionic liquid-based synergistic extraction strategy for rare earths?
  Yingbo Li,Nada Mehio,Huizhou Liu,Sheng Dai Green Chem., 2015,17, 2981-2993
• 5. Achieving excellent anti-corrosion and tribological performance by tailoring the surface morphology and chemical composition of aluminum alloys
  Wenjie Zhao,Hua Hou,Yuchun Jin,Zhixiang Zeng,Xuedong Wu,Qunji Xue RSC Adv., 2014,4, 60307-60315

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Aminopyridines and derivatives

Comprehensive Overview of 6-(Methylamino)-3-Pyridinemethanol (CAS No. 897951-48-3): Properties, Applications, and Research Insights

6-(Methylamino)-3-Pyridinemethanol (CAS No. 897951-48-3) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research due to its unique structural properties and potential applications. This pyridine derivative, characterized by its methylamino and hydroxymethyl functional groups, serves as a versatile intermediate in the synthesis of bioactive molecules. Its molecular formula, C₇H₁₀N₂O, and precise structure make it a valuable building block for drug discovery and material science.

In recent years, the demand for 6-(Methylamino)-3-Pyridinemethanol has surged, particularly in the context of small-molecule drug development and catalysis research. Researchers are increasingly exploring its role in designing kinase inhibitors and neurological therapeutics, aligning with trends in personalized medicine and targeted therapy. The compound’s ability to modulate enzyme activity and interact with biological receptors has positioned it as a candidate for treating chronic diseases, a topic frequently searched in academic and industrial databases.

The synthesis of 6-(Methylamino)-3-Pyridinemethanol typically involves multi-step organic reactions, including reductive amination and hydroxylation of pyridine precursors. Advanced techniques such as HPLC purification and NMR spectroscopy ensure high purity (>98%), a critical factor for its use in high-throughput screening (HTS) platforms. This aligns with the growing emphasis on quality-by-design (QbD) principles in pharmaceutical manufacturing, a hot topic in regulatory and compliance discussions.

From an industrial perspective, 6-(Methylamino)-3-Pyridinemethanol is often referenced in patents related to anticancer agents and anti-inflammatory drugs. Its low toxicity profile and solubility in polar solvents enhance its appeal for formulation development. Notably, searches for "pyridine derivatives in drug delivery" and "heterocyclic compound stability" have spiked in 2023, reflecting broader interest in optimizing such molecules for clinical use.

Environmental and safety considerations are also paramount. While 897951-48-3 is not classified as hazardous, its handling requires standard laboratory precautions. The compound’s biodegradability and eco-friendly synthesis routes resonate with the green chemistry movement, a trending focus area in sustainable pharmaceutical production. This addresses common queries like "sustainable intermediates for APIs" and "green synthesis of pyridine compounds."

In conclusion, 6-(Methylamino)-3-Pyridinemethanol exemplifies the intersection of innovation and practicality in modern chemistry. Its dual functionality, coupled with expanding applications in life sciences and material engineering, ensures its relevance in future research. As AI-driven drug discovery accelerates, compounds like this will remain pivotal in addressing unmet medical needs—a narrative frequently highlighted in scientific literature and industry reports.

• 32399-12-5([2-(methylamino)pyridin-3-yl]methanol)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)