• 1. Excellent kinetics of single-phase Gd-doped ceria fuel electrodes in solid oxide cells?
  Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
• 2. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 3. Fatty acid eutectic mixtures and derivatives from non-edible animal fat as phase change materials?
  Pau Gallart-Sirvent,Marc Martín,Gemma Villorbina,Mercè Balcells,Aran Solé,Luisa F. Cabeza,Ramon Canela-Garayoa RSC Adv., 2017,7, 24133-24139
• 4. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 5. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409

Quinolin-7-Amine Dihydrochloride: A Comprehensive Overview

Quinolin-7-amine dihydrochloride (CAS No. 897439-74-6) is a versatile compound with significant applications in various fields, including pharmaceuticals, materials science, and analytical chemistry. This compound, also referred to as 7-aminoquinoline dihydrochloride, has garnered attention due to its unique structural properties and potential for functionalization in diverse chemical systems.

The molecular structure of quinolin-7-amine dihydrochloride consists of a quinoline ring system with an amino group at the 7-position and two hydrochloric acid counterions. This configuration imparts the compound with both aromatic and amine functionalities, making it a valuable building block in organic synthesis. Recent studies have highlighted its role in the development of novel materials, such as fluorescent sensors and metal-organic frameworks (MOFs), where its amine groups facilitate coordination with metal ions.

One of the most promising applications of quinolin-7-amine dihydrochloride lies in its use as a precursor for bioactive molecules. Researchers have explored its potential in drug discovery, particularly in the design of anti-inflammatory and anticancer agents. For instance, a study published in *Journal of Medicinal Chemistry* demonstrated that derivatives of quinolin-7-amine exhibit potent inhibitory activity against key enzymes involved in inflammation pathways. These findings underscore the compound's potential as a lead molecule for therapeutic development.

In the realm of materials science, quinolin-7-amine dihydrochloride has been employed as a ligand in the synthesis of metal complexes with unique optical and electronic properties. A recent advancement reported in *Chemistry of Materials* showcased its use in creating luminescent materials for applications in optoelectronics and sensing technologies. The compound's ability to form stable coordination bonds with transition metals makes it an attractive candidate for such applications.

The synthesis of quinolin-7-amine dihydrochloride typically involves nucleophilic substitution or coupling reactions, depending on the desired product. Recent innovations in catalytic methods have enabled more efficient and environmentally friendly production processes. For example, the use of palladium-catalyzed cross-coupling reactions has significantly improved the yield and purity of this compound, making it more accessible for large-scale applications.

From an analytical chemistry perspective, quinolin-7-amine dihydrochloride has been utilized as a chiral selector in enantioselective separations. Its ability to interact selectively with enantiomeric compounds has made it valuable in the resolution of racemic mixtures, a critical step in drug manufacturing and natural product analysis.

Looking ahead, ongoing research is focused on expanding the functionalization possibilities of quinolin-7-amine dihydrochloride to unlock new applications. Collaborative efforts between chemists and biologists are exploring its potential as a scaffold for designing bio-inspired materials and smart sensors. These developments are expected to further solidify its position as an essential compound in modern chemical research.

• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)