Cas no 89690-65-3 (3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester)

3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester is a versatile heterocyclic compound featuring a pyridine core with a hydroxyl group at the 4-position and an ethyl ester moiety. This structure imparts reactivity suitable for applications in pharmaceutical intermediates and organic synthesis. The hydroxyl group enhances its potential as a building block for further functionalization, while the ester group offers stability and synthetic flexibility. Its balanced polarity and moderate solubility in common organic solvents facilitate its use in diverse reaction conditions. The compound is particularly valued for its role in constructing nitrogen-containing scaffolds, making it useful in medicinal chemistry and agrochemical research.
3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester structure
89690-65-3 structure
Product Name:3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester
CAS No:89690-65-3
MF:C8H13NO3
MW:171.193722486496
CID:592166
PubChem ID:343558
Update Time:2025-11-07

3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester Chemical and Physical Properties

Names and Identifiers

    • 1(2H)-Pyridinecarboxylic acid, 3,4-dihydro-4-hydroxy-, ethyl ester
    • ethyl 4-hydroxy-3,4-dihydro-2H-pyridine-1-carboxylate
    • DTXSID40321903
    • 4-hydroxy-1,2,3,4-tetrahydro-pyridine-1-carboxylic acid ethyl ester
    • NSC383239
    • ethyl 4-hydroxy-3,4-dihydro-1(2H)-pyridinecarboxylate
    • NSC-383239
    • 89690-65-3
    • 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester
    • Inchi: 1S/C8H13NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h3,5,7,10H,2,4,6H2,1H3
    • InChI Key: FCGREWKWOBEUCY-UHFFFAOYSA-N
    • SMILES: OC1C=CN(C(=O)OCC)CC1

Computed Properties

  • Exact Mass: 171.09
  • Monoisotopic Mass: 171.09
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 2
  • Complexity: 191
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.2
  • Topological Polar Surface Area: 49.8?2

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Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
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Additional information on 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester

3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester (CAS No. 89690-65-3)

The compound 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester, identified by the CAS registry number CAS No. 89690-65-3, is a significant molecule in the field of organic chemistry and pharmacology. This compound belongs to the class of pyridine derivatives, which have been extensively studied for their diverse biological activities and potential applications in drug development.

Recent studies have highlighted the importance of pyridine derivatives in medicinal chemistry, particularly due to their ability to modulate various cellular pathways and enzyme activities. The structure of 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester includes a pyridine ring with a hydroxyl group at the 4-position and an ethyl ester substituent at the 1-position. This unique structure contributes to its potential as a lead compound for the development of new therapeutic agents.

One of the most promising applications of this compound lies in its ability to act as a precursor for bioactive molecules. For instance, researchers have explored its role in the synthesis of anti-inflammatory and antioxidant agents. The hydroxyl group in the molecule plays a critical role in these activities, as it can participate in hydrogen bonding and other intermolecular interactions that are essential for biological function.

In addition to its direct biological effects, 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester has been utilized as an intermediate in the synthesis of more complex molecules. For example, recent advancements in asymmetric synthesis have enabled the construction of enantiomerically enriched derivatives of this compound, which are valuable for drug discovery programs targeting specific receptors or enzymes.

The synthesis of this compound has also been optimized in recent years. Traditional methods involving multi-step reactions have been replaced with more efficient protocols that minimize waste and improve yield. These improvements are critical for scaling up production, especially for compounds that are being considered for preclinical testing.

From an analytical standpoint, the characterization of CAS No. 89690-65-3 has benefited from advances in spectroscopic techniques such as NMR and mass spectrometry. These tools allow researchers to confirm the purity and structure of the compound with high precision, ensuring that subsequent studies are based on accurate data.

In conclusion, 3,4-Dihydro-4-hydroxy-1(2H)-pyridinecarboxylic Acid Ethyl Ester (CAS No. 89690-65-3) is a versatile compound with significant potential in medicinal chemistry and drug development. Its unique structure, combined with recent advances in synthesis and characterization techniques, positions it as a valuable tool for researchers seeking novel therapeutic agents.

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