Cas no 89464-29-9 (1-(1,3-thiazol-2-yl)propan-1-ol)

1-(1,3-Thiazol-2-yl)propan-1-ol is a heterocyclic organic compound featuring a thiazole ring linked to a propanol moiety. This structure imparts unique reactivity and functional versatility, making it valuable in pharmaceutical and agrochemical synthesis. The thiazole ring contributes to its potential as a bioactive intermediate, while the hydroxyl group enhances its solubility and derivatization potential. Its well-defined molecular architecture allows for precise modifications, facilitating applications in drug discovery and material science. The compound’s stability under standard conditions ensures reliable handling and storage. Its synthetic utility is further underscored by its compatibility with various coupling and functionalization reactions, making it a practical building block for complex molecular frameworks.
1-(1,3-thiazol-2-yl)propan-1-ol structure
89464-29-9 structure
Product Name:1-(1,3-thiazol-2-yl)propan-1-ol
CAS No:89464-29-9
MF:C6H9NOS
MW:143.206760168076
CID:711755
PubChem ID:15785702
Update Time:2025-10-29

1-(1,3-thiazol-2-yl)propan-1-ol Chemical and Physical Properties

Names and Identifiers

    • a-ethyl-2-Thiazolemethanol
    • 1-Thiazol-2-yl-propan-1-ol
    • 2-Thiazolemethanol, a-ethyl-
    • 2-Thiazolemethanol, -alpha--ethyl-
    • 1-(1,3-thiazol-2-yl)propan-1-ol
    • CS-0295812
    • 89464-29-9
    • VRCSHNZIEDOOBA-UHFFFAOYSA-N
    • AKOS015967785
    • EN300-1238976
    • 1-(thiazol-2-yl)propan-1-ol
    • SCHEMBL568277
    • Inchi: 1S/C6H9NOS/c1-2-5(8)6-7-3-4-9-6/h3-5,8H,2H2,1H3
    • InChI Key: VRCSHNZIEDOOBA-UHFFFAOYSA-N
    • SMILES: S1C=CN=C1C(CC)O

Computed Properties

  • Exact Mass: 143.04000
  • Monoisotopic Mass: 143.04048508g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 2
  • Complexity: 89.1
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 61.4?2

Experimental Properties

  • PSA: 61.36000
  • LogP: 1.58650

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Additional information on 1-(1,3-thiazol-2-yl)propan-1-ol

Comprehensive Overview of 1-(1,3-thiazol-2-yl)propan-1-ol (CAS No. 89464-29-9): Properties, Applications, and Industry Insights

1-(1,3-thiazol-2-yl)propan-1-ol (CAS No. 89464-29-9) is a specialized organic compound featuring a thiazole ring linked to a propanol moiety. This structural combination grants it unique physicochemical properties, making it valuable in pharmaceuticals, agrochemicals, and material science. The thiazole core, known for its electron-rich heterocyclic nature, enhances reactivity, while the hydroxyl group offers functional versatility. Researchers and industries are increasingly exploring its potential, particularly in drug intermediates and bioactive molecule synthesis.

In recent years, the demand for thiazole derivatives like 1-(1,3-thiazol-2-yl)propan-1-ol has surged due to their role in developing antimicrobial agents and anticancer compounds. A 2023 study highlighted its utility as a precursor for small-molecule inhibitors targeting enzyme pathways. This aligns with the growing focus on precision medicine and green chemistry, where efficient synthesis routes (e.g., catalytic hydrogenation) minimize waste. Users searching for "thiazole-based drug discovery" or "CAS 89464-29-9 applications" will find this compound relevant to cutting-edge research.

The compound's solubility in polar solvents (e.g., ethanol, DMSO) and stability under ambient conditions make it practical for lab-scale and industrial use. Analytical techniques like HPLC and NMR confirm its high purity (>98%), a critical factor for regulatory compliance in pharmaceutical manufacturing. Notably, its low toxicity profile (as per preliminary assays) positions it as a safer alternative to traditional halogenated intermediates, addressing sustainability concerns in chemical synthesis.

Emerging trends also link 1-(1,3-thiazol-2-yl)propan-1-ol to crop protection formulations. Its thiazole moiety disrupts fungal cell membranes, offering a template for next-generation fungicides. Agri-tech forums frequently discuss such derivatives under "eco-friendly pesticides," reflecting market shifts toward biodegradable solutions. Furthermore, patents filed between 2020–2024 highlight its incorporation into OLED materials, leveraging its electron-transport properties for flexible displays—a hotspot in material science innovations.

For suppliers and distributors, optimizing the supply chain of CAS No. 89464-29-9 requires adherence to REACH and GMP standards. Searches for "buy 1-(1,3-thiazol-2-yl)propan-1-ol" often prioritize vendors with ISO certification, underscoring quality expectations. Storage recommendations (e.g., inert atmosphere, 2–8°C) and MSDS documentation are equally critical to ensure safety and longevity, topics frequently queried in chemical procurement platforms.

In conclusion, 1-(1,3-thiazol-2-yl)propan-1-ol exemplifies the intersection of multidisciplinary chemistry and industrial demand. Its adaptability across life sciences and advanced materials sectors, coupled with stringent regulatory frameworks, ensures sustained relevance. Future research may explore its catalytic applications or polymeric composites, further expanding its commercial and scientific footprint.

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