Cas no 89448-35-1 (Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride)

Technical Introduction: Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride is a structurally unique bicyclic compound featuring both hydroxyl and aminomethyl functional groups, stabilized as a hydrochloride salt. Its rigid bicyclo[2.1.1]hexane scaffold confers enhanced steric and electronic properties, making it valuable for applications in medicinal chemistry and asymmetric synthesis. The hydrochloride form improves solubility and handling, while the functional groups offer versatile reactivity for further derivatization. This compound is particularly useful as a building block for designing constrained peptidomimetics or chiral ligands, where its fused ring system can enforce specific conformational preferences. Its synthetic utility and stability under standard conditions make it a practical choice for exploratory research and targeted molecular design.
Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride structure
89448-35-1 structure
Product Name:Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride
CAS No:89448-35-1
MF:C7H14ClNO
MW:163.645161151886
CID:600159
PubChem ID:13265788
Update Time:2025-11-02

Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride Chemical and Physical Properties

Names and Identifiers

    • Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride
    • 3-(aminomethyl)bicyclo[2.1.1]hexan-3-ol,hydrochloride
    • EN300-7646694
    • 2-(aminomethyl)bicyclo[2.1.1]hexan-2-ol;hydrochloride
    • 2-(Aminomethyl)bicyclo[2.1.1]hexan-2-ol--hydrogen chloride (1/1)
    • 89448-35-1
    • DTXSID00533106
    • EN300-39870069
    • (1s,4s)-2-(aminomethyl)bicyclo[2.1.1]hexan-2-ol hydrochloride
    • 2-(AMINOMETHYL)BICYCLO[2.1.1]HEXAN-2-OL HYDROCHLORIDE
    • Inchi: 1S/C7H13NO.ClH/c8-4-7(9)3-5-1-6(7)2-5;/h5-6,9H,1-4,8H2;1H
    • InChI Key: COFGLULCRGSTOW-UHFFFAOYSA-N
    • SMILES: Cl.OC1(CN)CC2CC1C2

Computed Properties

  • Exact Mass: 163.0763918g/mol
  • Monoisotopic Mass: 163.0763918g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 1
  • Complexity: 131
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 46.2?2

Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride Pricemore >>

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Additional information on Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride

Comprehensive Overview of Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride (CAS No. 89448-35-1)

Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride (CAS No. 89448-35-1) is a unique bicyclic compound with significant potential in pharmaceutical and chemical research. This compound, characterized by its bicyclo[2.1.1]hexane scaffold and aminomethyl functional group, has garnered attention for its structural novelty and diverse applications. Researchers are increasingly exploring its utility in drug discovery, particularly in the development of novel therapeutic agents targeting neurological and metabolic disorders.

The hydrochloride salt form of this compound enhances its solubility and stability, making it a preferred choice for laboratory and industrial applications. The presence of the aminomethyl group allows for further functionalization, enabling the synthesis of derivatives with tailored properties. This versatility has positioned Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride as a valuable building block in medicinal chemistry.

Recent studies have highlighted the potential of bicyclo[2.1.1]hexane derivatives in addressing challenges related to drug delivery and bioavailability. The rigid structure of the bicyclo[2.1.1]hexane core contributes to improved metabolic stability, a critical factor in the design of next-generation pharmaceuticals. As the demand for innovative drug candidates grows, compounds like Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride are becoming increasingly relevant.

In addition to its pharmaceutical applications, Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride is also being investigated for its role in materials science. The compound's unique geometry and functional groups make it a promising candidate for the development of advanced polymers and coatings. Researchers are exploring its potential to enhance the mechanical and thermal properties of these materials, addressing industry needs for high-performance solutions.

The synthesis of Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride involves sophisticated organic chemistry techniques, including catalytic hydrogenation and selective functionalization. These methods ensure high purity and yield, meeting the stringent requirements of research and industrial applications. As synthetic methodologies advance, the accessibility of this compound is expected to improve, further driving its adoption across various fields.

From an environmental perspective, the production and use of Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride are being scrutinized for sustainability. Green chemistry principles are being applied to minimize waste and reduce the environmental footprint of its synthesis. This aligns with the growing emphasis on sustainable practices in the chemical industry, making the compound a subject of interest for eco-conscious researchers and manufacturers.

Market trends indicate a rising demand for bicyclo[2.1.1]hexane-based compounds, driven by their expanding applications in pharmaceuticals and materials science. Analysts predict steady growth in the market for Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride, supported by ongoing research and development efforts. Companies specializing in fine chemicals and custom synthesis are increasingly offering this compound to meet the needs of their clients.

For researchers and industry professionals, understanding the properties and applications of Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride is essential. Its unique combination of structural features and functional groups opens up numerous possibilities for innovation. Whether in drug discovery, materials science, or sustainable chemistry, this compound represents a valuable tool for advancing scientific and industrial goals.

In conclusion, Bicyclo[2.1.1]hexan-2-ol, 2-(aminomethyl)-, hydrochloride (CAS No. 89448-35-1) is a compound of significant interest due to its versatile applications and potential for future development. Its role in pharmaceuticals, materials science, and sustainable chemistry underscores its importance in modern research and industry. As scientific understanding and technological capabilities continue to evolve, the impact of this compound is expected to grow, solidifying its place in the chemical landscape.

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