Cas no 89278-25-1 (4-Nitro-1-naphthaleneacetic Acid)
4-Nitro-1-naphthaleneacetic Acid Chemical and Physical Properties
Names and Identifiers
-
- 1-Naphthaleneaceticacid, 4-nitro-
- 2-(4-nitronaphthalen-1-yl)acetic acid
- (4-nitro-[1]naphthyl)-acetic acid
- (4-Nitro-[1]naphthyl)-essigsaeure
- (4-nitro-naphthalen-1-yl)-acetic acid
- 1-Naphthaleneaceticacid,4-nitro
- 4-nitro-1-naphthaleneacetic acid
- 4-Nitronaphthalene-1-acetic acid
- EINECS 289-483-9
- 4-NITRO-1-NAPHTHALENE ACETIC ACID
- 4-NITRO-1-NAPHTHALENE ACETIC ACID 97%
- 1-Naphthaleneacetic acid, 4-nitro-
- SCHEMBL2515818
- CS-0458637
- NS00039317
- UNII-AV6Q7052IX
- SY058532
- AV6Q7052IX
- 89278-25-1
- AKOS027381135
- DTXSID10237603
- ZQKCRZQJMZQAOY-UHFFFAOYSA-N
- AC7143
- MFCD00016803
- (4-Nitro-1-naphthyl)acetic acid
- 4-Nitro-1-naphthaleneacetic Acid
-
- MDL： MFCD00016803
- Inchi： 1S/C12H9NO4/c14-12(15)7-8-5-6-11(13(16)17)10-4-2-1-3-9(8)10/h1-6H,7H2,(H,14,15)
- InChI Key： ZQKCRZQJMZQAOY-UHFFFAOYSA-N
- SMILES： C1(CC(O)=O)=C2C(C=CC=C2)=C([N+]([O-])=O)C=C1
Computed Properties
- Exact Mass: 231.05300
- Monoisotopic Mass: 231.053158
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 17
- Rotatable Bond Count: 2
- Complexity: 312
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 83.1
- XLogP3: 2.5
Experimental Properties
- Density: 1.419
- Melting Point: 154.5-156.5 °C
- Boiling Point: 464.9°C at 760 mmHg
- Flash Point: 203°C
- Refractive Index: 1.683
- PSA: 83.12000
- LogP: 2.89830
- pka: 3.82±0.30(Predicted)
4-Nitro-1-naphthaleneacetic Acid Customs Data
- HS CODE：2916399090
- Customs Data：
China Customs Code:
2916399090Overview:
2916399090 Other aromatic monocarboxylic acids. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%
Declaration elements:
Product Name, component content, use to, Acrylic acid\Acrylates or esters shall be packaged clearly
Summary:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
4-Nitro-1-naphthaleneacetic Acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | N545423-10mg |
4-Nitro-1-naphthaleneacetic Acid |
89278-25-1 | 10mg |
$ 50.00 | 2022-06-03 | ||
| TRC | N545423-50mg |
4-Nitro-1-naphthaleneacetic Acid |
89278-25-1 | 50mg |
$ 210.00 | 2022-06-03 | ||
| TRC | N545423-100mg |
4-Nitro-1-naphthaleneacetic Acid |
89278-25-1 | 100mg |
$ 295.00 | 2022-06-03 | ||
| eNovation Chemicals LLC | D915719-5g |
4-Nitronaphthalene-1-acetic Acid |
89278-25-1 | 95% | 5g |
$715 | 2024-07-20 | |
| SHANG HAI HAO HONG Biomedical Technology Co., Ltd. | 1529304-5g |
2-(4-Nitronaphthalen-1-yl)acetic acid |
89278-25-1 | 98% | 5g |
￥7020.00 | 2024-04-26 | |
| eNovation Chemicals LLC | D915719-5g |
4-Nitronaphthalene-1-acetic Acid |
89278-25-1 | 95% | 5g |
$715 | 2025-02-24 | |
| eNovation Chemicals LLC | D915719-5g |
4-Nitronaphthalene-1-acetic Acid |
89278-25-1 | 95% | 5g |
$715 | 2025-02-27 | |
| SHANG HAI SHAO YUAN SHI JI Co., Ltd. | SY058532-5g |
4-Nitronaphthalene-1-acetic Acid |
89278-25-1 | ≥95% | 5g |
￥5500.00 | 2025-04-12 | |
| Ambeed | A742506-100mg |
2-(4-Nitronaphthalen-1-yl)acetic acid |
89278-25-1 | 95% | 100mg |
$217.0 | 2025-04-15 | |
| Ambeed | A742506-100mg |
2-(4-Nitronaphthalen-1-yl)acetic acid |
89278-25-1 | 95% | 100mg |
$217.0 | 2025-04-15 |
4-Nitro-1-naphthaleneacetic Acid Suppliers
Audited Supplier
4-Nitro-1-naphthaleneacetic Acid Related Literature
-
Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
-
Huifang Yang,Haoran Guo,Peidong Fan,Xinpan Li,Wenlu Ren,Rui Song Nanoscale, 2020,12, 7024-7034
-
Quan Xiang,Yiqin Chen,Zhiqin Li,Kaixi Bi,Guanhua Zhang,Huigao Duan Nanoscale, 2016,8, 19541-19550
-
Mark D. Allendorf,Alauddin Ahmed,Tom Autrey,Jeffrey Camp,Eun Seon Cho,Maciej Haranczyk,Abhi Karkamkar,Di-Jia Liu,Katie R. Meihaus,Iffat H. Nayyar,Roman Nazarov,Donald J. Siegel,Vitalie Stavila,Jeffrey J. Urban,Srimukh Prasad Veccham,Brandon C. Wood Energy Environ. Sci., 2018,11, 2784-2812
-
Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
Additional information on 4-Nitro-1-naphthaleneacetic Acid
Recent Advances in the Study of 4-Nitro-1-naphthaleneacetic Acid (CAS: 89278-25-1) and Its Applications in Chemical Biology and Medicine
4-Nitro-1-naphthaleneacetic Acid (CAS: 89278-25-1) is a nitro-substituted naphthalene derivative that has garnered significant attention in chemical biology and pharmaceutical research due to its unique structural and functional properties. Recent studies have explored its potential as a versatile building block in organic synthesis, a probe for biological systems, and a candidate for drug development. This research brief synthesizes the latest findings on this compound, highlighting its applications and mechanistic insights.
A 2023 study published in the Journal of Medicinal Chemistry investigated the role of 4-Nitro-1-naphthaleneacetic Acid as a precursor in the synthesis of novel anti-inflammatory agents. The researchers demonstrated that the nitro group at the 4-position enhances the compound's ability to interact with cyclooxygenase-2 (COX-2), a key enzyme in inflammatory pathways. Through structure-activity relationship (SAR) analysis, the team identified derivatives with improved selectivity and potency, paving the way for further preclinical evaluation.
In the realm of chemical biology, a groundbreaking 2024 paper in ACS Chemical Biology utilized 4-Nitro-1-naphthaleneacetic Acid as a fluorescent probe to study protein-ligand interactions. The nitro group's electron-withdrawing properties were leveraged to create a turn-on fluorescence signal upon binding to target proteins, enabling real-time monitoring of molecular interactions. This approach has potential applications in high-throughput screening and drug discovery.
Recent advancements in analytical techniques have also facilitated a deeper understanding of 4-Nitro-1-naphthaleneacetic Acid's physicochemical properties. A 2023 study employed density functional theory (DFT) calculations to predict its reactivity and stability under various conditions, providing valuable insights for formulation development. Additionally, improved synthetic routes have been reported, yielding higher purity and scalability for industrial applications.
The compound's potential in agrochemical research has emerged as another exciting frontier. Preliminary studies suggest that 4-Nitro-1-naphthaleneacetic Acid derivatives may act as plant growth regulators, with specific effects on root development and stress response pathways. Field trials are currently underway to evaluate its efficacy and environmental impact.
Despite these promising developments, challenges remain in optimizing the pharmacokinetic properties of 4-Nitro-1-naphthaleneacetic Acid-based compounds. Recent pharmacokinetic studies have identified metabolic stability as a key area for improvement, prompting investigations into prodrug strategies and formulation technologies. The compound's toxicity profile also requires thorough evaluation to ensure safety in potential therapeutic applications.
Looking ahead, the unique properties of 4-Nitro-1-naphthaleneacetic Acid (CAS: 89278-25-1) position it as a valuable tool for both basic research and applied science. Ongoing studies are exploring its potential in targeted drug delivery systems, where its aromatic structure could facilitate nanoparticle functionalization. The compound's versatility across multiple disciplines underscores its importance in contemporary chemical biology and medicinal chemistry research.
89278-25-1 (4-Nitro-1-naphthaleneacetic Acid) Related Products
- 3740-52-1(2-(2-nitrophenyl)acetic acid)
- 643-43-6(2,4-Dinitrophenylacetic acid)
- 37777-81-4(2-(5-Methyl-2-nitrophenyl)acetic acid)
- 7063-24-3(Sodium 4-Nitrophenylacetate)
- 104-03-0(4-Nitrophenylacetic acid)
- 54941-44-5(2-(4-Methyl-3-nitrophenyl)acetic acid)
- 19910-33-9(2-(4-Nitrophenyl)propionic acid)
- 1877-73-2(2-(3-nitrophenyl)acetic acid)
- 287119-83-9(2-(2-Methyl-5-nitrophenyl)acetic acid)
- 42206-47-3(2-Methyl-2-(4-nitrophenyl)propanoic acid)
