Cas no 887594-85-6 (3-(3-methoxyphenyl)methylpyrrolidine)

3-(3-Methoxyphenyl)methylpyrrolidine is a pyrrolidine derivative featuring a methoxyphenyl substituent, which enhances its utility as an intermediate in organic synthesis and pharmaceutical research. The methoxy group contributes to electron-rich aromatic properties, facilitating further functionalization, while the pyrrolidine core offers structural versatility for heterocyclic modifications. This compound is particularly valuable in the development of bioactive molecules due to its balanced lipophilicity and potential for receptor interactions. Its well-defined structure ensures reproducibility in synthetic applications, making it a reliable building block for medicinal chemistry and material science. The product is typically supplied with high purity, ensuring consistent performance in research and industrial processes.
3-(3-methoxyphenyl)methylpyrrolidine structure
887594-85-6 structure
Product Name:3-(3-methoxyphenyl)methylpyrrolidine
CAS No:887594-85-6
MF:C12H17NO
MW:191.269483327866
MDL:MFCD07383260
CID:890788
PubChem ID:53439759
Update Time:2025-11-02

3-(3-methoxyphenyl)methylpyrrolidine Chemical and Physical Properties

Names and Identifiers

    • 3-(3-METHOXY-BENZYL)-PYRROLIDINE
    • 3-(3-methoxybenzyl)pyrrolidine
    • 3-[(3-methoxyphenyl)methyl]pyrrolidine
    • 3-(3-methoxyphenyl)methylpyrrolidine
    • EN300-1275807
    • 887594-85-6
    • DTXSID90702142
    • AKOS006285861
    • CS-0232559
    • MDL: MFCD07383260
    • Inchi: 1S/C12H17NO/c1-14-12-4-2-3-10(8-12)7-11-5-6-13-9-11/h2-4,8,11,13H,5-7,9H2,1H3
    • InChI Key: FPHKCQIGHNFOKY-UHFFFAOYSA-N
    • SMILES: O(C)C1=CC=CC(=C1)CC1CNCC1

Computed Properties

  • Exact Mass: 191.13100
  • Monoisotopic Mass: 191.131014166g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 3
  • Complexity: 172
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.1
  • Topological Polar Surface Area: 21.3

Experimental Properties

  • PSA: 21.26000
  • LogP: 2.17600

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Additional information on 3-(3-methoxyphenyl)methylpyrrolidine

3-(3-Methoxyphenyl)methylpyrrolidine (CAS No. 887594-85-6): A Comprehensive Overview

3-(3-Methoxyphenyl)methylpyrrolidine (CAS No. 887594-85-6) is an organic compound belonging to the pyrrolidine derivative family. This compound has garnered significant attention in recent years due to its unique structural properties and potential applications in various fields, including pharmaceutical research, material science, and chemical synthesis. With the increasing demand for novel chemical entities in drug discovery, compounds like 3-(3-methoxyphenyl)methylpyrrolidine are being extensively studied for their bioactive potential.

The molecular structure of 3-(3-methoxyphenyl)methylpyrrolidine features a pyrrolidine ring substituted with a 3-methoxyphenyl group, which contributes to its distinct chemical behavior. Researchers are particularly interested in how the methoxy group influences the compound's reactivity and interaction with biological targets. This has led to numerous studies exploring its role as a building block in the synthesis of more complex molecules.

One of the most frequently asked questions about 3-(3-methoxyphenyl)methylpyrrolidine is its solubility and stability under different conditions. Studies indicate that this compound exhibits moderate solubility in common organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO). Its stability is generally good under standard laboratory conditions, making it a reliable candidate for further chemical modifications.

In the context of pharmaceutical applications, 3-(3-methoxyphenyl)methylpyrrolidine has been investigated for its potential as a central nervous system (CNS) agent. The pyrrolidine moiety is known to interact with various neurotransmitter systems, which could explain its relevance in neurological research. Additionally, the methoxy group may enhance the compound's ability to cross the blood-brain barrier, a critical factor in CNS drug development.

Another area of interest is the use of 3-(3-methoxyphenyl)methylpyrrolidine in material science. Its aromatic and aliphatic components make it a versatile precursor for designing new polymers and coatings. Researchers are exploring its potential in creating high-performance materials with improved thermal and mechanical properties. This aligns with the growing trend of developing sustainable and efficient materials for industrial applications.

The synthesis of 3-(3-methoxyphenyl)methylpyrrolidine typically involves multi-step organic reactions, including alkylation and reduction processes. Optimizing these synthetic routes is a key focus for chemists aiming to improve yield and purity. Recent advancements in green chemistry have also prompted the exploration of eco-friendly synthesis methods for this compound, addressing the increasing demand for sustainable chemical practices.

From a market perspective, the demand for 3-(3-methoxyphenyl)methylpyrrolidine is expected to rise, driven by its applications in drug discovery and material innovation. Suppliers and manufacturers are scaling up production to meet the needs of research institutions and industries. However, challenges such as cost-effective synthesis and regulatory compliance remain critical considerations for stakeholders.

In summary, 3-(3-methoxyphenyl)methylpyrrolidine (CAS No. 887594-85-6) is a promising compound with diverse applications in pharmaceuticals and materials science. Its unique structural features and bioactive potential make it a valuable subject for ongoing research. As scientific and industrial communities continue to explore its capabilities, this compound is likely to play a significant role in future innovations.

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