• 1. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
• 2. Dissociative electron attachment to HGaF4 Lewis–Br?nsted superacid
  Marcin Czapla,Jack Simons Phys. Chem. Chem. Phys., 2018,20, 21739-21745
• 3. Enabling high-throughput single-animal gene-expression studies with molecular and micro-scale technologies
  Jason Wan Lab Chip, 2020,20, 4528-4538
• 4. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
• 5. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Trifluoromethylbenzenes

Comprehensive Overview of 2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene (CAS No. 886503-84-0)

2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene (CAS No. 886503-84-0) is a specialized aromatic compound widely utilized in pharmaceutical, agrochemical, and material science research. This compound, featuring a unique trifluoromethyl group and methoxy substitution, has garnered significant attention due to its versatile applications in organic synthesis and drug discovery. Researchers and industry professionals frequently search for terms like "2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene synthesis", "CAS 886503-84-0 applications", and "trifluoromethyl benzene derivatives", reflecting its growing relevance in modern chemistry.

The molecular structure of 2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene combines electron-withdrawing (trifluoromethyl) and electron-donating (methoxy) groups, making it a valuable intermediate for designing bioactive molecules. Recent studies highlight its role in developing fluorinated pharmaceuticals, a trending topic in medicinal chemistry due to the enhanced metabolic stability and bioavailability imparted by fluorine atoms. Searches for "fluorine in drug design" and "trifluoromethyl benzene uses" underscore this connection.

In agrochemical applications, CAS 886503-84-0 serves as a precursor for herbicides and pesticides, aligning with the global demand for sustainable crop protection solutions. The compound’s stability under environmental conditions makes it a candidate for "green chemistry" innovations—a frequently searched term among environmentally conscious researchers. Its compatibility with catalytic reactions (another popular keyword) further enhances its appeal in industrial processes.

From a synthetic perspective, 2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene is often prepared via electrophilic aromatic substitution or cross-coupling reactions, methodologies widely discussed in academic forums. Queries like "how to introduce trifluoromethyl groups" and "methoxy benzene derivatives" reflect user interest in its preparation. Advanced techniques such as flow chemistry (a hot topic in process optimization) are also being explored to scale up its production efficiently.

The compound’s physicochemical properties—including its boiling point, solubility, and spectral data (common analytical search terms)—are critical for quality control. Analytical methods like HPLC, NMR, and GC-MS are typically employed for characterization, addressing frequent user questions about "CAS 886503-84-0 purity analysis". These details are vital for compliance with regulatory standards in pharmaceuticals and chemicals.

Emerging trends in material science have also spotlighted 2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene as a building block for organic electronic materials. With rising searches for "fluorinated polymers" and "high-performance materials", its role in developing flexible displays or conductive films aligns with cutting-edge research. This interdisciplinary potential makes it a compound of interest across multiple high-growth sectors.

In summary, 2-Chloro-1-Methoxy-3-(trifluoromethyl)benzene (CAS No. 886503-84-0) bridges fundamental research and industrial innovation. Its adaptability to green synthesis, relevance in drug discovery, and applications in advanced materials position it as a key player in contemporary chemistry. By addressing frequently searched keywords and integrating current scientific trends, this overview aims to serve as a trusted resource for professionals navigating its multifaceted uses.

• 76246-77-0(Benzene, 1-chloro-2-phenoxy-4-(trifluoromethyl)-)
• 406206-07-3(Benzene, 2-chloro-1-(3-methoxyphenoxy)-3-(trifluoromethyl)-)
• 138377-34-1(2-Chloro-3-hydroxybenzotrifluoride)
• 42874-96-4(2-chloro-1-(3-methylphenoxy)-4-(trifluoromethyl)benzene)
• 1214346-03-8(2-Chloro-4-methoxy-1-(trifluoromethyl)benzene)
• 1214340-18-7(2-chloro-1-methoxy-4-(trifluoromethyl)benzene)
• 406206-11-9(Phenol, 3-[2-chloro-3-(trifluoromethyl)phenoxy]-)
• 400-73-7(1-Chloro-4-methoxy-2-(trifluoromethyl)benzene)
• 1081849-77-5(1,5-dichloro-2-methoxy-4-(trifluoromethyl)benzene)
• 402-08-4(2-Chloro-5-(trifluoromethyl)anisole)