Cas no 886498-84-6 (1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one)
1-(2,6-Difluoro-4-methoxyphenyl)ethan-1-one is a fluorinated aromatic ketone characterized by its distinct substitution pattern, featuring two fluorine atoms at the ortho positions and a methoxy group at the para position relative to the acetyl moiety. This structural arrangement enhances its reactivity and selectivity in synthetic applications, particularly in pharmaceutical and agrochemical intermediates. The electron-withdrawing fluorine atoms and electron-donating methoxy group create a balanced electronic environment, making it a versatile building block for cross-coupling reactions, nucleophilic substitutions, and other transformations. Its high purity and stability under standard conditions ensure consistent performance in advanced chemical synthesis.
886498-84-6 structure
Product Name:1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one
CAS No:886498-84-6
MF:C9H8F2O2
MW:186.155429840088
MDL:MFCD04115921
CID:69325
PubChem ID:3853246
Update Time:2025-10-17
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one Chemical and Physical Properties
Names and Identifiers
-
- 1-(2,6-Difluoro-4-methoxyphenyl)ethanone
- 2 ,6 -Difluoro-4 -methoxyacetophenone
- 2',6'-Difluoro-4'-methoxyacetophenone
- JRD-1437
- 1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one
- AMY202100131
- MFCD04115921
- SCHEMBL2382494
- 1-(2,6-difluoro-4-methoxy-phenyl)ethanone
- YZVNPIUPAKOREH-UHFFFAOYSA-N
- MS-20106
- AC-26274
- CL9315
- A842810
- DTXSID40397345
- AKOS005256481
- EN300-201670
- 886498-84-6
- STL554733
- BBL100939
- 2'',6''-Difluoro-4''-methoxyacetophenone
-
- MDL： MFCD04115921
- Inchi： 1S/C9H8F2O2/c1-5(12)9-7(10)3-6(13-2)4-8(9)11/h3-4H,1-2H3
- InChI Key： YZVNPIUPAKOREH-UHFFFAOYSA-N
- SMILES： FC1C=C(C=C(C=1C(C)=O)F)OC
Computed Properties
- Exact Mass: 186.04900
- Monoisotopic Mass: 186.049
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 13
- Rotatable Bond Count: 2
- Complexity: 184
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 2
- XLogP3: 1.8
- Topological Polar Surface Area: 26.3A^2
Experimental Properties
- Density: 1.213
- Boiling Point: 224.2 °C at 760 mmHg
- Flash Point: 224.2 °C at 760 mmHg
- Refractive Index: 1.471
- PSA: 26.30000
- LogP: 2.17600
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | D452085-50mg |
2',6'-Difluoro-4'-methoxyacetophenone |
886498-84-6 | 50mg |
$ 50.00 | 2022-06-05 | ||
| TRC | D452085-100mg |
2',6'-Difluoro-4'-methoxyacetophenone |
886498-84-6 | 100mg |
$ 65.00 | 2022-06-05 | ||
| TRC | D452085-500mg |
2',6'-Difluoro-4'-methoxyacetophenone |
886498-84-6 | 500mg |
$ 185.00 | 2022-06-05 | ||
| Apollo Scientific | PC520530-1g |
2',6'-Difluoro-4'-methoxyacetophenone |
886498-84-6 | 97% | 1g |
￡104.00 | 2023-09-02 | |
| Apollo Scientific | PC520530-5g |
2',6'-Difluoro-4'-methoxyacetophenone |
886498-84-6 | 97% | 5g |
￡368.00 | 2023-09-02 | |
| Enamine | EN300-201670-1g |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one |
886498-84-6 | 95% | 1g |
$71.0 | 2023-09-16 | |
| Enamine | EN300-201670-5g |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one |
886498-84-6 | 95% | 5g |
$253.0 | 2023-09-16 | |
| Enamine | EN300-201670-10g |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one |
886498-84-6 | 95% | 10g |
$409.0 | 2023-09-16 | |
| Enamine | EN300-201670-0.05g |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one |
886498-84-6 | 95% | 0.05g |
$19.0 | 2023-09-16 | |
| Enamine | EN300-201670-0.1g |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one |
886498-84-6 | 95% | 0.1g |
$25.0 | 2023-09-16 |
1-(2,6-difluoro-4-methoxyphenyl)ethan-1-one Related Literature
-
Zhixia Liu,Tingjian Chen,Floyd E. Romesberg Chem. Sci., 2017,8, 8179-8182
-
Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
-
Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
-
Max Attwood,Hiroki Akutsu,Lee Martin,Toby J. Blundell,Pierre Le Maguere,Scott S. Turner Dalton Trans., 2021,50, 11843-11851
-
Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577
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