Cas no 886497-81-0 (2-Fluoro-5-(trifluoromethoxy)benzaldehyde)

2-Fluoro-5-(trifluoromethoxy)benzaldehyde is a fluorinated aromatic aldehyde with the molecular formula C?H?F?O?. This compound features both fluorine and trifluoromethoxy substituents on the benzene ring, enhancing its electron-withdrawing properties and making it a valuable intermediate in organic synthesis. Its unique structure contributes to high reactivity in cross-coupling reactions, nucleophilic substitutions, and other transformations, particularly in pharmaceutical and agrochemical applications. The presence of fluorine atoms improves metabolic stability and lipophilicity in derived compounds. This aldehyde is typically used in the development of bioactive molecules, offering precise control over electronic and steric effects in target structures. It is supplied as a high-purity solid with consistent quality for research and industrial use.
2-Fluoro-5-(trifluoromethoxy)benzaldehyde structure
886497-81-0 structure
Product Name:2-Fluoro-5-(trifluoromethoxy)benzaldehyde
CAS No:886497-81-0
MF:C8H4F4O2
MW:208.109776496887
MDL:MFCD04115886
CID:93158
PubChem ID:2783324
Update Time:2025-06-09

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Chemical and Physical Properties

Names and Identifiers

    • 2-Fluoro-5-(trifluoromethoxy)benzaldehyde
    • 2-Fluoro-5-(trifluoromethyl)benzaldehyde
    • C8H4F4O2
    • Benzaldehyde,2-fluoro-5-(trifluoromethoxy)-
    • 2-FLUORO-5-TRIFLUOROMETHOXYBENZALDEHYDE
    • PubChem4231
    • FMDGCHMPSCBYFX-UHFFFAOYSA-N
    • 4525AC
    • SBB093984
    • PC1092
    • DT2095
    • AM62130
    • FCH1322270
    • TRA0039098
    • 2-Fluoro-5-trifluoromethoxy-benzaldehyde
    • AB0068218
    • AX8074931
    • ST24040610
    • Benzaldehyde,
    • 2-Fluoro-5-(trifluoromethoxy)benzaldehyde (ACI)
    • 886497-81-0
    • MFCD04115886
    • J-509433
    • PS-8041
    • 2-Formyl-4-(trifluoromethoxy)fluorobenzene
    • SY106761
    • SCHEMBL2824893
    • AC-3850
    • AKOS005063846
    • EN300-794513
    • CS-W015237
    • DTXSID70382582
    • Z1269187130
    • DTXCID40333607
    • MDL： MFCD04115886
    • Inchi： 1S/C8H4F4O2/c9-7-2-1-6(3-5(7)4-13)14-8(10,11)12/h1-4H
    • InChI Key： FMDGCHMPSCBYFX-UHFFFAOYSA-N
    • SMILES： O=CC1C(F)=CC=C(OC(F)(F)F)C=1

Computed Properties

  • Exact Mass: 208.01500
  • Monoisotopic Mass: 208.015
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 2
  • Complexity: 204
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 26.3
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.7

Experimental Properties

  • Color/Form: Colorless to grayish yellow liquid
  • Density: 1.428
  • Boiling Point: 200.4°C at 760 mmHg
  • Flash Point: 73℃
  • Refractive Index: 1.4430
  • Water Partition Coefficient: Slightly miscible with water.
  • PSA: 26.30000
  • LogP: 2.53680
  • Sensitiveness: Air Sensitive
  • Solubility: Unable to mix or difficult to mix in water

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Security Information

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Customs Data

  • HS CODE：2913000090
  • Customs Data：

    China Customs Code:

    2913000090

    Overview:

    2913000090 Item2912Other derivatives of the listed products [refer to halogenation,sulfonation,Nitrosative or nitrosative derivatives]. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-MS645-1g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
1g
 218.0CNY 2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-MS645-5g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
5g
 865.0CNY 2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.
B-MS645-200mg
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
200mg
 77.0CNY 2021-08-04
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
F810182-25g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
25g
 1,530.00 2021-05-17
TRC
F599170-50mg
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0
50mg
 $ 50.00 2022-06-04
TRC
F599170-100mg
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0
100mg
 $ 65.00 2022-06-04
TRC
F599170-500mg
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0
500mg
 $ 80.00 2022-06-04
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R016465-1g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
1g
 ￥75 2024-05-21
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R016465-25g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
25g
 ￥1246 2024-05-21
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R016465-5g
2-Fluoro-5-(trifluoromethoxy)benzaldehyde
 886497-81-0 97%
5g
 ￥255 2024-05-21

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Production Method

2-Fluoro-5-(trifluoromethoxy)benzaldehyde Related Literature

Related Categories

886497-81-0 (2-Fluoro-5-(trifluoromethoxy)benzaldehyde) Related Products

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
上海嶸奧生物技術(shù)有限公司
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
上海嶸奧生物技術(shù)有限公司
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shenzhen Jianxing Pharmaceutical Technology Co., Ltd.
Hangzhou Cedareal Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Hangzhou Cedareal Technology Co., Ltd.
SHOCHEM(SHANGHAI) CO.,lTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
SHOCHEM(SHANGHAI) CO.,lTD