Cas no 885518-27-4 (Methyl 4-fluoro-1H-indole-6-carboxylate)
Methyl 4-fluoro-1H-indole-6-carboxylate is a fluorinated indole derivative with significant utility in pharmaceutical and agrochemical research. The incorporation of a fluorine atom at the 4-position enhances metabolic stability and bioavailability, making it a valuable intermediate in drug discovery. The methyl ester group at the 6-position provides a reactive handle for further functionalization, facilitating the synthesis of diverse heterocyclic compounds. Its well-defined structure and high purity ensure reproducibility in synthetic applications. This compound is particularly useful in the development of bioactive molecules, including kinase inhibitors and antimicrobial agents, due to its favorable physicochemical properties and compatibility with modern coupling reactions.
885518-27-4 structure
Product Name:Methyl 4-fluoro-1H-indole-6-carboxylate
CAS No:885518-27-4
MF:C10H8FNO2
MW:193.174426078796
MDL:MFCD07357296
CID:840694
PubChem ID:24728024
Update Time:2025-05-27
Methyl 4-fluoro-1H-indole-6-carboxylate Chemical and Physical Properties
Names and Identifiers
-
- Methyl 4-fluoro-1H-indole-6-carboxylate
- 1H-Indole-6-carboxylic acid, 4-fluoro-, Methyl ester
- 4-Fluoro-6-indole carboxylic acid methyl ester
- Methyl 4-fluoro-1H-indole-6-carboxylate (ACI)
- 4-FLUORO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER
- AKOS006284310
- Methyl4-fluoro-1H-indole-6-carboxylate
- SB15123
- CS-0036521
- DTXSID00646109
- AS-77050
- 885518-27-4
- 1H-INDOLE-6-CARBOXYLIC ACID,4-FLUORO-,METHYL ESTER
-
- MDL： MFCD07357296
- Inchi： 1S/C10H8FNO2/c1-14-10(13)6-4-8(11)7-2-3-12-9(7)5-6/h2-5,12H,1H3
- InChI Key： PKCZOOJRXJCMPM-UHFFFAOYSA-N
- SMILES： O=C(C1C=C2C(C=CN2)=C(F)C=1)OC
Computed Properties
- Exact Mass: 193.05390666g/mol
- Monoisotopic Mass: 193.05390666g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 14
- Rotatable Bond Count: 2
- Complexity: 234
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2
- Topological Polar Surface Area: 42.1?2
Methyl 4-fluoro-1H-indole-6-carboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | GL274-1g |
Methyl4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 97% | 1g |
5489CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | GL274-250mg |
Methyl4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 97% | 250mg |
1669CNY | 2021-05-08 | |
| TRC | M706738-1mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 1mg |
$ 50.00 | 2022-06-03 | ||
| TRC | M706738-2mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 2mg |
$ 65.00 | 2022-06-03 | ||
| TRC | M706738-10mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 10mg |
$ 135.00 | 2022-06-03 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M27850-1g |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 1g |
￥3950.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M27850-500mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 500mg |
￥2140.0 | 2021-09-08 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | M27850-250mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 250mg |
￥1130.0 | 2021-09-08 | ||
| ChemScence | CS-0036521-100mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 98.23% | 100mg |
$120.0 | 2022-04-26 | |
| ChemScence | CS-0036521-250mg |
Methyl 4-fluoro-1H-indole-6-carboxylate |
885518-27-4 | 98.23% | 250mg |
$200.0 | 2022-04-26 |
Methyl 4-fluoro-1H-indole-6-carboxylate Related Literature
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
Kay S. McMillan,Anthony G. McCluskey,Annette Sorensen,Marie Boyd,Michele Zagnoni Analyst, 2016,141, 100-110
-
Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
-
Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
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