• 1. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 2. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 3. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
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• 4. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
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• 5. Evidence of pre-micellar aggregates in aqueous solution of amphiphilic PDMS–PEO block copolymer?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Benzoic acids

Comprehensive Analysis of 2-Furancarboxylic acid,5-(2-carboxyphenyl)- (CAS No. 88460-78-0): Properties, Applications, and Industry Trends

2-Furancarboxylic acid,5-(2-carboxyphenyl)-, identified by its CAS No. 88460-78-0, is a specialized organic compound with a unique molecular structure combining furan and benzoic acid moieties. This bifunctional molecule has garnered significant attention in pharmaceutical, agrochemical, and material science research due to its versatile reactivity. The compound's dual carboxyl groups enable diverse derivatization pathways, making it a valuable intermediate for synthesizing complex molecules.

Recent advancements in green chemistry have highlighted the potential of furan-based compounds like 5-(2-carboxyphenyl)-2-furancarboxylic acid as sustainable alternatives to petroleum-derived chemicals. With growing interest in bio-based materials, researchers are exploring its applications in polymer modification and biodegradable plastics. The compound's aromaticity and hydrogen-bonding capacity contribute to interesting photophysical properties, relevant for developing organic electronic materials.

The synthesis of CAS 88460-78-0 typically involves multi-step organic reactions, with careful control of reaction conditions to optimize yield and purity. Analytical characterization using HPLC-MS and NMR spectroscopy confirms its structural integrity. In pharmaceutical applications, its framework serves as a precursor for heterocyclic drug development, particularly in designing molecules with improved bioavailability and target specificity.

Market trends indicate rising demand for specialty carboxylic acids like this compound, driven by innovations in drug delivery systems and functional materials. Regulatory considerations emphasize proper handling procedures, though it doesn't fall under restricted categories. Storage recommendations include protection from moisture and extreme temperatures to maintain stability.

Ongoing research explores novel derivatives of 2-Furancarboxylic acid,5-(2-carboxyphenyl)- for catalysis applications and coordination chemistry. Its metal-chelating properties show promise in developing new ligand systems for transition metal complexes. The compound's environmental fate and ecotoxicological profile are subjects of current investigation to ensure sustainable use across industries.

Quality control protocols for CAS No. 88460-78-0 typically involve chromatographic purity assessment and spectroscopic verification. Suppliers often provide technical specifications including minimum purity levels (usually ≥95%) and appropriate analytical certificates. The compound's structure-activity relationships continue to be studied for rational design of more efficient chemical entities in various applications.

From a commercial perspective, 5-(2-carboxyphenyl)furan-2-carboxylic acid remains a niche product with specialized suppliers catering to research institutions and industrial laboratories. Pricing reflects the complexity of its synthesis and purification processes. Recent patent literature reveals growing intellectual property activity surrounding its derivatives, particularly in medicinal chemistry and material science applications.

The future outlook for this compound appears promising as interdisciplinary research uncovers new potential uses. Its combination of aromatic systems and functional groups positions it as a valuable building block in molecular design. As analytical techniques advance, deeper understanding of its physicochemical properties will likely reveal additional applications in emerging technological fields.

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