Cas no 876473-56-2 (4-Amino-5-methoxy-2-methylphenol)

4-Amino-5-methoxy-2-methylphenol is an organic compound primarily used as an intermediate in the synthesis of dyes, pharmaceuticals, and specialty chemicals. Its molecular structure, featuring both amino and methoxy functional groups, enables versatile reactivity in coupling and substitution reactions. The compound exhibits good solubility in polar solvents, facilitating its use in various chemical processes. Its stability under controlled conditions ensures reliable performance in synthetic applications. Additionally, the presence of the methyl group enhances selectivity in certain reactions, making it valuable for fine chemical synthesis. Proper handling and storage are recommended to maintain its integrity and prevent degradation.
4-Amino-5-methoxy-2-methylphenol structure
876473-56-2 structure
Product Name:4-Amino-5-methoxy-2-methylphenol
CAS No:876473-56-2
MF:C8H11NO2
MW:153.178442239761
CID:709936
PubChem ID:76851371
Update Time:2025-10-29

4-Amino-5-methoxy-2-methylphenol Chemical and Physical Properties

Names and Identifiers

    • Phenol,4-amino-5-methoxy-2-methyl-
    • o-Cresol, 4-amino-5-methoxy- (3CI)
    • 4-Amino-5-methoxy-2-methylphenol
    • Inchi: 1S/C8H11NO2/c1-5-3-6(9)8(11-2)4-7(5)10/h3-4,10H,9H2,1-2H3
    • InChI Key: ISHITNOWKSRKFS-UHFFFAOYSA-N
    • SMILES: O(C)C1C=C(C(C)=CC=1N)O

Computed Properties

  • Exact Mass: 153.079
  • Monoisotopic Mass: 153.079
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 129
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 55.5

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Additional information on 4-Amino-5-methoxy-2-methylphenol

Comprehensive Guide to 4-Amino-5-methoxy-2-methylphenol (CAS No. 876473-56-2): Properties, Applications, and Industry Insights

4-Amino-5-methoxy-2-methylphenol (CAS No. 876473-56-2) is a specialized organic compound widely recognized for its unique chemical structure and versatile applications in pharmaceuticals, cosmetics, and industrial research. This phenol derivative features an amino group, methoxy substituent, and methyl group, making it a valuable intermediate in synthetic chemistry. With growing interest in hair dye intermediates and antioxidant precursors, this compound has garnered significant attention in both academic and industrial circles.

The molecular formula of 4-Amino-5-methoxy-2-methylphenol is C8H11NO2, with a molecular weight of 153.18 g/mol. Its CAS number 876473-56-2 serves as a critical identifier in chemical databases and regulatory documentation. Researchers often explore its solubility in organic solvents, melting point range, and stability under various pH conditions—key parameters for formulation development. Recent studies highlight its potential as a building block for drug discovery, particularly in designing molecules with targeted biological activity.

In the cosmetic industry, 4-Amino-5-methoxy-2-methylphenol is frequently discussed in forums about permanent hair color formulations and oxidative dye systems. Its ability to form stable chromophores when coupled with developers like hydrogen peroxide makes it a preferred choice for long-lasting hair coloration. Consumers searching for "ammonia-free hair dye ingredients" or "non-toxic colorants" often encounter this compound in patent literature and safety assessments.

From an environmental perspective, the biodegradability and eco-friendly synthesis routes of CAS 876473-56-2 are active research areas. Green chemistry initiatives focus on optimizing its production using catalytic methods and renewable feedstocks, addressing concerns about sustainable manufacturing. Analytical techniques like HPLC purity testing and mass spectrometry characterization ensure compliance with international quality standards such as ISO and REACH.

Market trends indicate rising demand for 4-Amino-5-methoxy-2-methylphenol in Asia-Pacific regions, driven by expanding personal care industries. Frequently searched queries include "buy 876473-56-2 in bulk", "technical datasheet PDF", and "alternative names for 4-Amino-5-methoxy-2-methylphenol". Suppliers emphasize its low impurity profile and batch-to-batch consistency to differentiate product offerings.

Innovative applications continue to emerge, such as its use in electronic material coatings and photostabilizers for polymers. Researchers investigating "UV-absorbing compounds" or "conductive organic materials" may find this phenol derivative relevant to their work. Patent analyses reveal its incorporation in advanced material systems requiring thermal resistance and optical clarity.

Safety evaluations confirm that proper handling of 4-Amino-5-methoxy-2-methylphenol requires standard laboratory precautions. While not classified as hazardous under GHS criteria, material safety data sheets (MSDS) recommend glove protection and ventilation controls during processing. These precautions align with industry best practices for handling fine chemical powders.

The future outlook for CAS 876473-56-2 remains positive, with ongoing investigations into its structure-activity relationships and derivative synthesis. As regulatory frameworks evolve, particularly concerning cosmetic ingredient transparency, this compound's well-documented safety profile positions it favorably for continued use. Industry conferences increasingly feature discussions about its role in next-generation specialty chemicals.

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