• 1. Excimer–monomer switch: a reaction-based approach for selective detection of fluoride?
  Qiao Song,Angela Bamesberger,Lingyun Yang,Haley Houtwed,Haishi Cao Analyst, 2014,139, 3588-3592
• 2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 3. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 4. Establishing the accuracy of position-specific carbon isotope analysis of propane by GC-pyrolysis-GC-IRMS
  ChangjieLiu,PengLiu,XiaofengWang,XiaoqiangLi,JuskeHorita
• 5. Ester-directed orthogonal dual C–H activation and ortho aryl C–H alkenylation via distal weak coordination?
  Manickam Bakthadoss,Tadiparthi Thirupathi Reddy,Vishal Agarwal,Duddu S. Sharada Chem. Commun., 2022,58, 1406-1409

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Phenylpyrazoles
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Azoles Pyrazoles Phenylpyrazoles

Comprehensive Overview of 3-Phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine Dihydrochloride (CAS No. 87628-50-0)

3-Phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine Dihydrochloride (CAS No. 87628-50-0) is a heterocyclic compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural properties. This compound belongs to the pyrazolo[4,3-c]pyridine family, a class of nitrogen-containing heterocycles known for their versatility in drug discovery. The dihydrochloride salt form enhances its solubility, making it a preferred choice for experimental studies. Researchers are particularly interested in its potential applications in central nervous system (CNS) disorders and inflammatory diseases, aligning with current trends in precision medicine and targeted therapies.

The molecular structure of 3-Phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine Dihydrochloride features a phenyl group attached to a fused pyrazolo-pyridine ring system. This configuration contributes to its bioactivity and binding affinity toward various biological targets. Recent studies highlight its role as a scaffold for kinase inhibitors, a hot topic in oncology research. With the rise of AI-driven drug discovery, computational models frequently analyze this compound for its ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) properties, addressing common queries about its pharmacokinetic profile.

In the context of green chemistry, synthetic routes for CAS No. 87628-50-0 are being optimized to reduce environmental impact. This aligns with the growing demand for sustainable synthesis methods, a frequently searched topic among chemists. The compound’s stability under physiological conditions also makes it a candidate for prodrug development, another area of high interest in pharmaceutical forums. Analytical techniques like HPLC and NMR are routinely employed to characterize its purity, ensuring compliance with Good Manufacturing Practices (GMP).

Beyond its pharmaceutical potential, 3-Phenyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine Dihydrochloride is explored in material science for its photophysical properties. Its conjugated system allows for applications in organic electronics, such as OLEDs, resonating with advancements in renewable energy technologies. Safety data sheets (SDS) emphasize its non-hazardous nature, addressing concerns about lab safety and regulatory compliance—a recurring theme in industrial and academic discussions.

In summary, CAS No. 87628-50-0 represents a multifaceted compound with broad relevance across drug development, materials engineering, and sustainable chemistry. Its adaptability to cutting-edge research trends, such as AI-augmented molecular design and green synthesis, ensures its continued prominence in scientific literature. For researchers seeking high-purity reference standards or custom synthesis options, this compound remains a valuable asset in advancing innovation.

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