Cas no 872678-33-6 (Naphthalene,1-chloro-6-methoxy-)

Naphthalene,1-chloro-6-methoxy- is a chlorinated and methoxylated naphthalene derivative with applications in organic synthesis and specialty chemical production. Its structure, featuring both chloro and methoxy functional groups, makes it a versatile intermediate for further chemical modifications, such as nucleophilic substitutions or coupling reactions. The compound’s reactivity allows for selective transformations, enabling the synthesis of complex aromatic systems. It is typically used in research and industrial settings where precise functionalization of naphthalene frameworks is required. Proper handling is essential due to potential hazards associated with chlorinated aromatics. Storage should be in a cool, dry environment, protected from light to maintain stability.
Naphthalene,1-chloro-6-methoxy- structure
872678-33-6 structure
Product Name:Naphthalene,1-chloro-6-methoxy-
CAS No:872678-33-6
MF:C11H9ClO
MW:192.641562223434
CID:719469
PubChem ID:23035872
Update Time:2025-08-05

Naphthalene,1-chloro-6-methoxy- Chemical and Physical Properties

Names and Identifiers

    • Naphthalene,1-chloro-6-methoxy-
    • 1-Chloro-6-methoxynaphthalene
    • Naphthalene, 1-chloro-6-methoxy- (9CI)
    • 872678-33-6
    • DTXSID20629954
    • Naphthalene,1-chloro-6-methoxy-(9ci)
    • AKOS024437567
    • FT-0741503
    • SCHEMBL8749346
    • Inchi: 1S/C11H9ClO/c1-13-9-5-6-10-8(7-9)3-2-4-11(10)12/h2-7H,1H3
    • InChI Key: UVCVWODBQUZXKE-UHFFFAOYSA-N
    • SMILES: ClC1=CC=CC2=CC(=CC=C21)OC

Computed Properties

  • Exact Mass: 192.03400
  • Monoisotopic Mass: 192.0341926g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 1
  • Complexity: 172
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 3.9
  • Topological Polar Surface Area: 9.2?2

Experimental Properties

  • PSA: 9.23000
  • LogP: 3.50180

Naphthalene,1-chloro-6-methoxy- Pricemore >>

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Additional information on Naphthalene,1-chloro-6-methoxy-

Recent Advances in the Study of Naphthalene,1-chloro-6-methoxy- (CAS: 872678-33-6) in Chemical Biology and Pharmaceutical Research

Naphthalene,1-chloro-6-methoxy- (CAS: 872678-33-6) is a chemical compound that has garnered significant attention in recent years due to its potential applications in chemical biology and pharmaceutical research. This compound, characterized by its naphthalene core substituted with a chlorine atom at the 1-position and a methoxy group at the 6-position, exhibits unique physicochemical properties that make it a promising candidate for various biomedical applications. Recent studies have explored its synthesis, biological activity, and potential therapeutic uses, shedding light on its role in drug discovery and development.

One of the key areas of interest in the study of Naphthalene,1-chloro-6-methoxy- is its synthesis and structural modification. Researchers have developed novel synthetic routes to produce this compound with high yield and purity, enabling further investigation of its properties. Advanced techniques such as NMR spectroscopy and mass spectrometry have been employed to confirm its structure and purity. These synthetic advancements have paved the way for the exploration of its biological activities, including its interactions with cellular targets and potential as a lead compound in drug design.

In the realm of biological activity, recent studies have demonstrated that Naphthalene,1-chloro-6-methoxy- exhibits notable pharmacological properties. For instance, it has shown inhibitory effects on specific enzymes involved in inflammatory pathways, suggesting its potential as an anti-inflammatory agent. Additionally, preliminary studies have indicated its ability to modulate certain receptor activities, which could be leveraged in the development of therapeutics for neurological disorders. These findings highlight the compound's versatility and its potential to address unmet medical needs.

Another significant aspect of the research on Naphthalene,1-chloro-6-methoxy- is its application in medicinal chemistry. Researchers have explored its use as a scaffold for the design of novel drug candidates. By modifying its structure, scientists have been able to enhance its bioavailability, selectivity, and potency. Computational modeling and molecular docking studies have further elucidated its binding interactions with target proteins, providing valuable insights for rational drug design. These efforts underscore the compound's potential as a cornerstone in the development of new therapeutic agents.

Despite the promising findings, challenges remain in the study of Naphthalene,1-chloro-6-methoxy-. For example, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion (ADME), require further investigation to assess its suitability as a drug candidate. Additionally, toxicological studies are needed to evaluate its safety profile. Addressing these challenges will be crucial for translating the compound's potential into clinical applications.

In conclusion, Naphthalene,1-chloro-6-methoxy- (CAS: 872678-33-6) represents a compelling area of research in chemical biology and pharmaceutical sciences. Recent advancements in its synthesis, biological activity, and medicinal chemistry applications have highlighted its potential as a therapeutic agent. Continued research efforts will be essential to fully unlock its capabilities and address the remaining challenges. This compound holds promise for contributing to the development of innovative treatments for various diseases, making it a valuable focus for future studies.

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