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  Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
• 2. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 3. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Halobenzenes Fluorobenzenes

Comprehensive Overview of 2,4-Dibromo-6-fluorophenylboronic acid (CAS No. 870778-96-4)

2,4-Dibromo-6-fluorophenylboronic acid (CAS No. 870778-96-4) is a specialized boronic acid derivative widely utilized in organic synthesis, pharmaceutical research, and material science. This compound belongs to the class of arylboronic acids, which are pivotal in Suzuki-Miyaura cross-coupling reactions—a cornerstone of modern drug discovery and agrochemical development. Its unique structure, featuring bromine and fluorine substituents, enhances reactivity and selectivity in palladium-catalyzed reactions, making it a valuable intermediate for constructing complex molecules.

The growing demand for 2,4-Dibromo-6-fluorophenylboronic acid is driven by its applications in high-performance materials and bioconjugation. Researchers are increasingly exploring its role in OLEDs (Organic Light-Emitting Diodes) and fluorescent probes, aligning with trends in sustainable electronics and bioimaging. A surge in searches for "boronic acid Suzuki coupling" and "fluorinated arylboronates" reflects its relevance in cutting-edge chemistry. Additionally, its stability under aqueous conditions makes it suitable for biomedical applications, a topic frequently queried in AI-driven drug design platforms.

From a synthetic perspective, CAS No. 870778-96-4 is often discussed alongside "halogenated boronic acids" and "directed ortho-metalation" techniques. Its electron-withdrawing groups (bromine and fluorine) facilitate regioselective functionalization, a feature highlighted in recent publications on C-H activation. This aligns with industry interest in "green chemistry" and "atom-efficient synthesis," as users seek eco-friendly alternatives to traditional methods. The compound’s crystalline purity (>98%) also meets stringent requirements for API (Active Pharmaceutical Ingredient) production.

In material science, 2,4-Dibromo-6-fluorophenylboronic acid is gaining traction for designing covalent organic frameworks (COFs)—a hot topic in nanotechnology forums. Its ability to form self-assembled monolayers (SAMs) on metal surfaces is under investigation for sensor development, particularly in environmental monitoring. Searches for "boronic acid sensors" and "heavy metal detection" underscore this niche application. Furthermore, its compatibility with microwave-assisted synthesis addresses queries about "fast-track organic synthesis," a common pain point for industrial chemists.

Quality control of CAS No. 870778-96-4 involves advanced analytical techniques like HPLC and NMR spectroscopy, ensuring compliance with REACH and FDA guidelines. Discussions on "boronic acid stability" often cite its robust shelf-life under inert conditions, a critical factor for long-term storage. As the pharmaceutical industry shifts toward continuous manufacturing, this compound’s scalability in flow chemistry setups is another area of exploration.

In summary, 2,4-Dibromo-6-fluorophenylboronic acid exemplifies the intersection of medicinal chemistry and advanced materials. Its versatility in catalysis, bioconjugation, and nanostructure engineering positions it as a key player in solving contemporary challenges, from targeted drug delivery to smart material design. The compound’s alignment with trending search terms like "boronic acid applications 2024" and "fluorinated building blocks" ensures its continued prominence in scientific discourse.

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