Cas no 870692-96-9 (3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide)

3-Amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide is a heterocyclic compound featuring a thiophene core substituted with an amino group, a 4-methoxyphenyl moiety, and a carbohydrazide functional group. This structure imparts versatility in synthetic applications, particularly as a key intermediate in the preparation of pharmacologically active molecules, such as heterocyclic hydrazones and thiophene-based derivatives. Its reactive amino and hydrazide groups enable facile derivatization, making it valuable for medicinal chemistry and material science research. The methoxyphenyl substituent enhances solubility and electronic properties, facilitating further functionalization. The compound is characterized by high purity and stability, ensuring reliable performance in synthetic workflows. Its well-defined structure supports precise molecular design in drug discovery and organic synthesis.
3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide structure
870692-96-9 structure
Product Name:3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide
CAS No:870692-96-9
MF:C12H13N3O2S
MW:263.315521001816
CID:3108600
PubChem ID:7131039
Update Time:2025-05-21

3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide Chemical and Physical Properties

Names and Identifiers

    • 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide
    • G26742
    • EN300-14706
    • Z104442598
    • 870692-96-9
    • AKOS005137353
    • Inchi: 1S/C12H13N3O2S/c1-17-8-4-2-7(3-5-8)10-6-9(13)11(18-10)12(16)15-14/h2-6H,13-14H2,1H3,(H,15,16)
    • InChI Key: NENIEAAZERKIKT-UHFFFAOYSA-N
    • SMILES: S1C(C(NN)=O)=C(C=C1C1C=CC(=CC=1)OC)N

Computed Properties

  • Exact Mass: 263.07284784Da
  • Monoisotopic Mass: 263.07284784Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 3
  • Complexity: 295
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2
  • Topological Polar Surface Area: 119?2

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3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide Related Literature

Additional information on 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide

3-Amino-5-(4-Methoxyphenyl)Thiophene-2-Carbohydrazide: A Comprehensive Overview

The compound with CAS No. 870692-96-9, commonly referred to as 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide, is a fascinating molecule that has garnered significant attention in the fields of organic chemistry and materials science. This compound is characterized by its unique structure, which combines a thiophene ring with an amino group and a methoxyphenyl substituent. The combination of these functional groups imparts distinctive chemical properties, making it a valuable compound for various applications.

Recent studies have highlighted the potential of 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide in drug design and development. Its ability to act as a ligand in metalloenzyme inhibition has been explored in several research papers. For instance, a 2023 study published in the *Journal of Medicinal Chemistry* demonstrated that this compound exhibits potent inhibitory activity against certain proteases, suggesting its potential as a lead compound for anti-inflammatory and antiviral therapies.

In addition to its biological applications, 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide has also been investigated for its electronic properties. Researchers have reported that this compound can serve as a building block for constructing advanced materials, such as organic semiconductors and sensors. A 2023 paper in *Advanced Materials* detailed how this compound's electron-rich thiophene ring facilitates charge transport, making it suitable for use in flexible electronics and optoelectronic devices.

The synthesis of 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide involves a multi-step process that typically begins with the preparation of the thiophene derivative. The introduction of the amino group and the methoxyphenyl substituent requires precise control over reaction conditions to ensure high yields and purity. Recent advancements in catalytic methods have enabled more efficient syntheses, reducing production costs and improving scalability.

From an environmental standpoint, 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide has been evaluated for its biodegradability and eco-friendliness. Studies conducted in 2023 indicate that this compound exhibits moderate biodegradation rates under aerobic conditions, making it a more sustainable option compared to some traditional organic compounds used in industrial applications.

In conclusion, 3-amino-5-(4-methoxyphenyl)thiophene-2-carbohydrazide (CAS No. 870692-96-9) is a versatile compound with promising applications across multiple disciplines. Its unique chemical structure, combined with recent advancements in synthesis and application research, positions it as a key player in the development of novel drugs, electronic materials, and sustainable chemical processes.

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