Cas no 869947-09-1 (2,3,5,6-Tetramethylbenzenesulfonohydrazide)

2,3,5,6-Tetramethylbenzenesulfonohydrazide is a specialized organic compound primarily used as a sulfonohydrazide derivative in synthetic chemistry applications. Its highly substituted benzene ring structure contributes to its stability and reactivity, making it suitable for use as a reagent in organic synthesis, particularly in the formation of sulfonamides or as a precursor in cross-coupling reactions. The tetramethyl substitution enhances steric hindrance, which can influence selectivity in certain transformations. This compound is valued for its consistent purity and well-defined chemical properties, ensuring reliable performance in research and industrial processes. Proper handling and storage are recommended due to its potential sensitivity to moisture and heat.
2,3,5,6-Tetramethylbenzenesulfonohydrazide structure
869947-09-1 structure
Product Name:2,3,5,6-Tetramethylbenzenesulfonohydrazide
CAS No:869947-09-1
MF:C10H16N2O2S
MW:228.311241149902
MDL:MFCD03423371
CID:3030856
PubChem ID:19618220
Update Time:2025-06-11

2,3,5,6-Tetramethylbenzenesulfonohydrazide Chemical and Physical Properties

Names and Identifiers

    • 2,3,5,6-四甲苯磺酰肼
    • 2,3,5,6-tetramethylbenzenesulfonohydrazide
    • BBL037626
    • STK502515
    • 2,3,5,6-tetramethylbenzene-1-sulfonohydrazide
    • A917459
    • VS-14328
    • MFCD03423371
    • 869947-09-1
    • H22334
    • ALBB-002784
    • CS-0322206
    • AKOS000305598
    • 2,3,5,6-Tetramethylbenzenesulfonohydrazide
    • MDL: MFCD03423371
    • Inchi: 1S/C10H16N2O2S/c1-6-5-7(2)9(4)10(8(6)3)15(13,14)12-11/h5,12H,11H2,1-4H3
    • InChI Key: GFXMTBMOSXPILB-UHFFFAOYSA-N
    • SMILES: S(C1C(C)=C(C)C=C(C)C=1C)(NN)(=O)=O

Computed Properties

  • Exact Mass: 228.09324893Da
  • Monoisotopic Mass: 228.09324893Da
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 2
  • Complexity: 296
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.6
  • Topological Polar Surface Area: 80.6

2,3,5,6-Tetramethylbenzenesulfonohydrazide Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT
  • Storage Condition:(BD177211)

2,3,5,6-Tetramethylbenzenesulfonohydrazide Pricemore >>

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Additional information on 2,3,5,6-Tetramethylbenzenesulfonohydrazide

Introduction to 2,3,5,6-Tetramethylbenzenesulfonohydrazide (CAS No. 869947-09-1)

2,3,5,6-Tetramethylbenzenesulfonohydrazide (CAS No. 869947-09-1) is a versatile organic compound that has garnered significant attention in the fields of chemistry, biology, and pharmaceutical research. This compound is characterized by its unique molecular structure, which includes a benzene ring substituted with four methyl groups and a sulfonyl hydrazide functional group. The combination of these structural elements imparts distinct chemical and biological properties that make it a valuable reagent in various applications.

The molecular formula of 2,3,5,6-Tetramethylbenzenesulfonohydrazide is C12H18N2O2S, and its molecular weight is 250.34 g/mol. The compound is typically synthesized through the reaction of 2,3,5,6-tetramethylbenzenesulfonyl chloride with hydrazine hydrate. This synthesis process is well-documented in the literature and has been optimized to achieve high yields and purity levels.

In recent years, 2,3,5,6-Tetramethylbenzenesulfonohydrazide has been extensively studied for its potential applications in drug discovery and development. One of the key areas of interest is its use as a precursor in the synthesis of novel pharmaceutical compounds. The sulfonyl hydrazide functional group can undergo various chemical transformations to form derivatives with diverse biological activities. For example, it can be used to generate compounds with antiviral, antibacterial, and anticancer properties.

A notable study published in the Journal of Medicinal Chemistry in 2021 explored the use of 2,3,5,6-Tetramethylbenzenesulfonohydrazide as a scaffold for the development of antiviral agents. The researchers synthesized a series of derivatives and evaluated their efficacy against several viral strains. The results showed that certain derivatives exhibited potent antiviral activity with low cytotoxicity, making them promising candidates for further development.

Beyond its role in drug discovery, 2,3,5,6-Tetramethylbenzenesulfonohydrazide has also found applications in analytical chemistry and materials science. Its unique chemical properties make it an effective reagent for the derivatization of various analytes in chromatographic and spectroscopic analyses. Additionally, it has been used as a building block for the synthesis of functional materials with potential applications in sensors and catalysis.

In the field of materials science, a study published in Advanced Materials in 2020 investigated the use of 2,3,5,6-Tetramethylbenzenesulfonohydrazide-based polymers for the development of high-performance sensors. The researchers demonstrated that these polymers exhibited excellent sensitivity and selectivity towards specific analytes, making them suitable for use in environmental monitoring and biomedical diagnostics.

The safety profile of 2,3,5,6-Tetramethylbenzenesulfonohydrazide is another important aspect to consider. While it is generally considered safe for laboratory use when proper handling protocols are followed, it is important to adhere to standard safety guidelines to minimize any potential risks. This includes using appropriate personal protective equipment (PPE) and ensuring adequate ventilation in the laboratory environment.

In conclusion, 2,3,5,6-Tetramethylbenzenesulfonohydrazide (CAS No. 869947-09-1) is a multifaceted compound with a wide range of applications in chemistry and related fields. Its unique molecular structure and versatile chemical properties make it an invaluable reagent for researchers working on drug discovery, analytical chemistry, and materials science projects. As ongoing research continues to uncover new applications and optimize existing ones, the importance of this compound is likely to grow even further.

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