Cas no 866318-88-9 (5-Chloro-3-ethynylpyridin-2-amine)
5-Chloro-3-ethynylpyridin-2-amine is a versatile pyridine derivative featuring a chloro substituent at the 5-position and an ethynyl group at the 3-position, with an amine functionality at the 2-position. This compound serves as a valuable intermediate in pharmaceutical and agrochemical synthesis, particularly in the development of heterocyclic compounds. Its ethynyl group enables efficient cross-coupling reactions, such as Sonogashira or click chemistry, while the chloro and amine functionalities offer additional reactivity for further derivatization. The structural features of this compound make it useful for constructing complex molecular architectures in medicinal chemistry and materials science. Its stability and well-defined reactivity profile contribute to its utility in targeted synthetic applications.
866318-88-9 structure
Product Name:5-Chloro-3-ethynylpyridin-2-amine
CAS No:866318-88-9
MF:C7H5ClN2
MW:152.581000089645
MDL:MFCD10758079
CID:1027484
PubChem ID:25918667
Update Time:2025-10-14
5-Chloro-3-ethynylpyridin-2-amine Chemical and Physical Properties
Names and Identifiers
-
- 5-Chloro-3-ethynylpyridin-2-amine
- 5-Chloro-3-ethynyl-2-pyridinamine
- CC-0812
- 5-chloro-3-ethynylpyridin-2-amine;
- 5-chloro-3-ethynyl-pyridin-2-ylamine
- J-517343
- 866318-88-9
- MFCD10758079
- CS-0315522
- DTXSID60649772
- AKOS005071995
- SCHEMBL1748895
- A863104
- 5-chloro-3-ethynylpyridin-2-ylamine
- MJENWHNACWVDES-UHFFFAOYSA-N
- AMY32362
- 5-Chloro-3-ethynyl-2-aMinopyridine
-
- MDL： MFCD10758079
- Inchi： 1S/C7H5ClN2/c1-2-5-3-6(8)4-10-7(5)9/h1,3-4H,(H2,9,10)
- InChI Key： MJENWHNACWVDES-UHFFFAOYSA-N
- SMILES： ClC1=CN=C(C(C#C)=C1)N
Computed Properties
- Exact Mass: 152.01400
- Monoisotopic Mass: 152.0141259g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 10
- Rotatable Bond Count: 0
- Complexity: 160
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 1.4
- Topological Polar Surface Area: 38.9?2
Experimental Properties
- Density: 1.3±0.1 g/cm3
- Boiling Point: 275.7±40.0 °C at 760 mmHg
- Flash Point: 120.5±27.3 °C
- PSA: 38.91000
- LogP: 1.87970
- Vapor Pressure: 0.0±0.6 mmHg at 25°C
5-Chloro-3-ethynylpyridin-2-amine Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
5-Chloro-3-ethynylpyridin-2-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Matrix Scientific | 046632-500mg |
5-Chloro-3-ethynyl-2-pyridinamine, >95% |
866318-88-9 | >95% | 500mg |
$362.00 | 2023-09-08 | |
| Fluorochem | 226223-250mg |
5-Chloro-3-ethynylpyridin-2-amine |
866318-88-9 | 95% | 250mg |
￡255.00 | 2022-02-28 | |
| Fluorochem | 226223-1g |
5-Chloro-3-ethynylpyridin-2-amine |
866318-88-9 | 95% | 1g |
￡637.00 | 2022-02-28 | |
| Fluorochem | 226223-5g |
5-Chloro-3-ethynylpyridin-2-amine |
866318-88-9 | 95% | 5g |
￡1910.00 | 2022-02-28 | |
| Chemenu | CM171125-1g |
5-Chloro-3-ethynyl-2-pyridinamine |
866318-88-9 | 95% | 1g |
$542 | 2021-08-05 | |
| Alichem | A029193680-1g |
5-Chloro-3-ethynylpyridin-2-amine |
866318-88-9 | 95% | 1g |
$582.98 | 2023-08-31 | |
| Alichem | A029193680-5g |
5-Chloro-3-ethynylpyridin-2-amine |
866318-88-9 | 95% | 5g |
$1764.88 | 2023-08-31 | |
| Apollo Scientific | OR303787-100mg |
2-Amino-5-chloro-3-ethynylpyridine |
866318-88-9 | 100mg |
￡198.00 | 2023-09-02 | ||
| Apollo Scientific | OR303787-250mg |
2-Amino-5-chloro-3-ethynylpyridine |
866318-88-9 | 250mg |
￡295.00 | 2023-09-02 | ||
| Chemenu | CM171125-1g |
5-Chloro-3-ethynyl-2-pyridinamine |
866318-88-9 | 95% | 1g |
$542 | 2023-01-02 |
5-Chloro-3-ethynylpyridin-2-amine Related Literature
-
Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
-
Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
-
Ivor Lon?ari? Phys. Chem. Chem. Phys., 2015,17, 9436-9445
-
David White,Sean R. Stowell Biomater. Sci., 2017,5, 463-474
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
866318-88-9 (5-Chloro-3-ethynylpyridin-2-amine) Related Products
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- 1173019-45-8(2-Amino-5-chloro-3-methylpyridine hemihydrate)
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- 1214369-39-7([3,3'-Bipyridin]-2-amine, 5-chloro-)
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